SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q04WJ4

- PYRF_LEPBL

UniProt

Q04WJ4 - PYRF_LEPBL

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Orotidine 5'-phosphate decarboxylase
Gene
pyrF, LBL_4241
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Orotidine 5'-phosphate = UMP + CO2.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei97 – 971Proton donor By similarity

GO - Molecular functioni

  1. orotidine-5'-phosphate decarboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' UMP biosynthetic process Source: UniProtKB-UniPathway
  2. 'de novo' pyrimidine nucleobase biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Biological processi

Pyrimidine biosynthesis

Enzyme and pathway databases

BioCyciLBOR355276:GHUQ-3239-MONOMER.
UniPathwayiUPA00070; UER00120.

Names & Taxonomyi

Protein namesi
Recommended name:
Orotidine 5'-phosphate decarboxylase (EC:4.1.1.23)
Alternative name(s):
OMP decarboxylase
Short name:
OMPDCase
Short name:
OMPdecase
Gene namesi
Name:pyrF
Ordered Locus Names:LBL_4241
OrganismiLeptospira borgpetersenii serovar Hardjo-bovis (strain L550)
Taxonomic identifieri355276 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000000655: Chromosome 2

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 271271Orotidine 5'-phosphate decarboxylaseUniRule annotation
PRO_1000138955Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi355276.LBL_4241.

Structurei

3D structure databases

ProteinModelPortaliQ04WJ4.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0284.
HOGENOMiHOG000245747.
KOiK01591.
OMAiCRTSNAG.
OrthoDBiEOG6DZF33.

Family and domain databases

Gene3Di3.20.20.70. 1 hit.
HAMAPiMF_01215. OMPdecase_type2.
InterProiIPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view]
PfamiPF00215. OMPdecase. 1 hit.
[Graphical view]
SMARTiSM00934. OMPdecase. 1 hit.
[Graphical view]
SUPFAMiSSF51366. SSF51366. 1 hit.
TIGRFAMsiTIGR02127. pyrF_sub2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04WJ4-1 [UniParc]FASTAAdd to Basket

« Hide

MNFQSKFLTR SQSLKSLLCV GLDPDYCKLP EIIKRSPEPL VHFCREIIDA    50
TAPYAVAYKP NIAFFEVFGS SGIRQFEKVI GHLKNNYPQI PIVADIKRGD 100
LDNTARQYAR YYFGDLQVDS LTLSPYMGLD TLRPFLEYQD HLVFWLCLTS 150
NPDSIQFQKK RFSETGRTLY EEVAYVANSI SPLNLGFVVG ATNTYELEIL 200
RKQNPDRIFL IPGFGAQGAK LDDLLPVCGR YSLINSSRGI HFASDGLDFA 250
ARANQEAEKI HNAMQARFVF L 271
Length:271
Mass (Da):30,740
Last modified:November 14, 2006 - v1
Checksum:i95FEA5770250F67E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000349 Genomic DNA. Translation: ABJ80551.1.
RefSeqiYP_799484.1. NC_008509.1.

Genome annotation databases

EnsemblBacteriaiABJ80551; ABJ80551; LBL_4241.
GeneIDi4409195.
KEGGilbl:LBL_4241.
PATRICi22371555. VBILepBor75619_4220.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000349 Genomic DNA. Translation: ABJ80551.1 .
RefSeqi YP_799484.1. NC_008509.1.

3D structure databases

ProteinModelPortali Q04WJ4.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 355276.LBL_4241.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ80551 ; ABJ80551 ; LBL_4241 .
GeneIDi 4409195.
KEGGi lbl:LBL_4241.
PATRICi 22371555. VBILepBor75619_4220.

Phylogenomic databases

eggNOGi COG0284.
HOGENOMi HOG000245747.
KOi K01591.
OMAi CRTSNAG.
OrthoDBi EOG6DZF33.

Enzyme and pathway databases

UniPathwayi UPA00070 ; UER00120 .
BioCyci LBOR355276:GHUQ-3239-MONOMER.

Family and domain databases

Gene3Di 3.20.20.70. 1 hit.
HAMAPi MF_01215. OMPdecase_type2.
InterProi IPR013785. Aldolase_TIM.
IPR011995. OMPdecase_type-2.
IPR001754. OMPdeCOase_dom.
IPR011060. RibuloseP-bd_barrel.
[Graphical view ]
Pfami PF00215. OMPdecase. 1 hit.
[Graphical view ]
SMARTi SM00934. OMPdecase. 1 hit.
[Graphical view ]
SUPFAMi SSF51366. SSF51366. 1 hit.
TIGRFAMsi TIGR02127. pyrF_sub2. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: L550.

Entry informationi

Entry nameiPYRF_LEPBL
AccessioniPrimary (citable) accession number: Q04WJ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi