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Q04W85

- LFTR_LEPBJ

UniProt

Q04W85 - LFTR_LEPBJ

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Protein

Leucyl/phenylalanyl-tRNA--protein transferase

Gene
aat, LBJ_0088
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine By similarity.UniRule annotation

Catalytic activityi

L-leucyl-tRNA(Leu) + [protein] = tRNA(Leu) + L-leucyl-[protein].UniRule annotation
L-phenylalanyl-tRNA(Phe) + [protein] = tRNA + L-phenylalanyl-[protein].UniRule annotation

GO - Molecular functioni

  1. leucyltransferase activity Source: UniProtKB-EC

GO - Biological processi

  1. protein catabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciLBOR355277:GHYM-86-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucyl/phenylalanyl-tRNA--protein transferase (EC:2.3.2.6)
Alternative name(s):
L/F-transferase
Leucyltransferase
Phenyalanyltransferase
Gene namesi
Name:aat
Ordered Locus Names:LBJ_0088
OrganismiLeptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Taxonomic identifieri355277 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000000656: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 219219Leucyl/phenylalanyl-tRNA--protein transferaseUniRule annotationPRO_0000304339Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi355277.LBJ_0088.

Structurei

3D structure databases

ProteinModelPortaliQ04W85.

Family & Domainsi

Sequence similaritiesi

Belongs to the L/F-transferase family.

Phylogenomic databases

eggNOGiCOG2360.
HOGENOMiHOG000102325.
KOiK00684.
OMAiERFRYPR.
OrthoDBiEOG6WX4R3.

Family and domain databases

HAMAPiMF_00688. Leu_Phe_trans.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view]
PfamiPF03588. Leu_Phe_trans. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
TIGRFAMsiTIGR00667. aat. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04W85-1 [UniParc]FASTAAdd to Basket

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MKDFSDFFRN PHIWDREIVA VGGDLSPERL LYAYKNGIFP WSDQPILWYC    50
LDPRGIFDLN KLHISKRLKR KINQKRYTIT FNRAFEQVMR CCAYRPGEET 100
WITDLFIKSY TEFHKLGYAH SIEVWDENGN LGGGVYGVAI GNFFAGESMF 150
SFISDFGKIG LFHLFEALKK DQFTLFDTQQ LNIVTLCLGA YQIPKKEYLR 200
RLESAVASGK KWNPLRTVF 219
Length:219
Mass (Da):25,580
Last modified:November 14, 2006 - v1
Checksum:i4C245826995D425D
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000350 Genomic DNA. Translation: ABJ74835.1.
RefSeqiYP_799593.1. NC_008510.1.

Genome annotation databases

EnsemblBacteriaiABJ74835; ABJ74835; LBJ_0088.
GeneIDi4411101.
KEGGilbj:LBJ_0088.
PATRICi22354746. VBILepBor13265_0104.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000350 Genomic DNA. Translation: ABJ74835.1 .
RefSeqi YP_799593.1. NC_008510.1.

3D structure databases

ProteinModelPortali Q04W85.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 355277.LBJ_0088.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ74835 ; ABJ74835 ; LBJ_0088 .
GeneIDi 4411101.
KEGGi lbj:LBJ_0088.
PATRICi 22354746. VBILepBor13265_0104.

Phylogenomic databases

eggNOGi COG2360.
HOGENOMi HOG000102325.
KOi K00684.
OMAi ERFRYPR.
OrthoDBi EOG6WX4R3.

Enzyme and pathway databases

BioCyci LBOR355277:GHYM-86-MONOMER.

Family and domain databases

HAMAPi MF_00688. Leu_Phe_trans.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR004616. Leu/Phe-tRNA_Trfase.
[Graphical view ]
Pfami PF03588. Leu_Phe_trans. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
TIGRFAMsi TIGR00667. aat. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JB197.

Entry informationi

Entry nameiLFTR_LEPBJ
AccessioniPrimary (citable) accession number: Q04W85
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 11, 2007
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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