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Q04RU6

- UVRC_LEPBJ

UniProt

Q04RU6 - UVRC_LEPBJ

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Protein
UvrABC system protein C
Gene
uvrC, LBJ_1853
Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision By similarity.UniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-HAMAP
  2. excinuclease ABC activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. SOS response Source: UniProtKB-HAMAP
  2. nucleotide-excision repair Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Excision nuclease

Keywords - Biological processi

DNA damage, DNA excision, DNA repair, SOS response

Enzyme and pathway databases

BioCyciLBOR355277:GHYM-1829-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UvrABC system protein C
Short name:
Protein UvrC
Alternative name(s):
Excinuclease ABC subunit C
Gene namesi
Name:uvrC
Ordered Locus Names:LBJ_1853
OrganismiLeptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Taxonomic identifieri355277 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000000656: Chromosome 1

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
  2. excinuclease repair complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 609609UvrABC system protein CUniRule annotation
PRO_1000077803Add
BLAST

Interactioni

Subunit structurei

Interacts with UvrB in an incision complex By similarity.

Protein-protein interaction databases

STRINGi355277.LBJ_1853.

Structurei

3D structure databases

ProteinModelPortaliQ04RU6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini19 – 9779GIY-YIG
Add
BLAST
Domaini208 – 24336UVR
Add
BLAST

Sequence similaritiesi

Belongs to the UvrC family.
Contains 1 GIY-YIG domain.
Contains 1 UVR domain.

Phylogenomic databases

eggNOGiCOG0322.
HOGENOMiHOG000279960.
KOiK03703.
OMAiYLVITNE.
OrthoDBiEOG6K13R9.

Family and domain databases

Gene3Di3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPiMF_00203. UvrC.
InterProiIPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view]
PfamiPF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view]
SMARTiSM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view]
SUPFAMiSSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsiTIGR00194. uvrC. 1 hit.
PROSITEiPS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04RU6-1 [UniParc]FASTAAdd to Basket

« Hide

MPEILNHILI LEKIKNLGIS PGCYLWKSRK GEVLYIGKAK NLDKRVRNYL    50
KENHPDIKTR ALQKEIFDLD WIATGTEKEA LILEATLIKK HNPRFNVRFK 100
DDKKYPYICV SLSESFPMVY ITRKLKDNGD RYFGPYSDVK STRETLDIIL 150
RIFPVRKTRQ VLPLPKPRRP CLNFDMGRCL GPCQGNIPVE DYKIVIDQVI 200
QFLEGKKESL VGDLSIKMSA SSNRMDFEKA ARYRDMLQRI QNFREKQTVV 250
SAEGGDEDVI GFARKKDEGQ VILLEVRGGR LETKKSFPIQ GVLDAEDSEI 300
LGAFFRDYYL NAALVPPLIF VPADIQEETA AVMDVLQEKT GFRPKLKSPR 350
GGDKRSLLKI AEKNAELGLT ERLLATHYRD QTASLKEIQE MFSLEHPPHI 400
IECYDISHFQ GSEPVASGVM FVEGKPFKQG YRKYNIRGYK GINDPGMIHE 450
VISRRLQRIA NEESVFPDLI VIDGGPTQLA KACEAAMEAG AERIPMIGLA 500
KKREEIYFPG DNEPFIFDMN SSGMKLLRHL RDEAHRFGVS HHRSRRNKET 550
MRSLIQNVPD IGLKRSKLLL RHFSGEKKIE DATKEELLAV PGIGENLAEK 600
ILKRIRKKE 609
Length:609
Mass (Da):69,680
Last modified:November 14, 2006 - v1
Checksum:iA7F6FE524049C19A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000350 Genomic DNA. Translation: ABJ76374.1.
RefSeqiYP_801132.1. NC_008510.1.

Genome annotation databases

EnsemblBacteriaiABJ76374; ABJ76374; LBJ_1853.
GeneIDi4409998.
KEGGilbj:LBJ_1853.
PATRICi22359348. VBILepBor13265_2381.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000350 Genomic DNA. Translation: ABJ76374.1 .
RefSeqi YP_801132.1. NC_008510.1.

3D structure databases

ProteinModelPortali Q04RU6.
ModBasei Search...

Protein-protein interaction databases

STRINGi 355277.LBJ_1853.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ76374 ; ABJ76374 ; LBJ_1853 .
GeneIDi 4409998.
KEGGi lbj:LBJ_1853.
PATRICi 22359348. VBILepBor13265_2381.

Phylogenomic databases

eggNOGi COG0322.
HOGENOMi HOG000279960.
KOi K03703.
OMAi YLVITNE.
OrthoDBi EOG6K13R9.

Enzyme and pathway databases

BioCyci LBOR355277:GHYM-1829-MONOMER.

Family and domain databases

Gene3Di 3.40.1440.10. 1 hit.
4.10.860.10. 1 hit.
HAMAPi MF_00203. UvrC.
InterProi IPR027299. GIY-YIG_dom.
IPR000305. GIY-YIG_SF.
IPR003583. Hlx-hairpin-Hlx_DNA-bd_motif.
IPR010994. RuvA_2-like.
IPR001943. UVR_dom.
IPR004791. UvrC.
IPR001162. UvrC_homol_region.
[Graphical view ]
Pfami PF01541. GIY-YIG. 1 hit.
PF02151. UVR. 1 hit.
PF08459. UvrC_HhH_N. 1 hit.
[Graphical view ]
SMARTi SM00465. GIYc. 1 hit.
SM00278. HhH1. 2 hits.
[Graphical view ]
SUPFAMi SSF46600. SSF46600. 1 hit.
SSF47781. SSF47781. 1 hit.
SSF82771. SSF82771. 1 hit.
TIGRFAMsi TIGR00194. uvrC. 1 hit.
PROSITEi PS50164. GIY_YIG. 1 hit.
PS50151. UVR. 1 hit.
PS50165. UVRC. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JB197.

Entry informationi

Entry nameiUVRC_LEPBJ
AccessioniPrimary (citable) accession number: Q04RU6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi