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Protein
Submitted name:

Oxoglutarate dehydrogenase (Lipoamide), dehydrogenase (E1) component

Gene

sucA

Organism
Leptospira borgpetersenii serovar Hardjo-bovis (strain JB197)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Enzyme and pathway databases

BioCyciLBOR355277:GHYM-2097-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Oxoglutarate dehydrogenase (Lipoamide), dehydrogenase (E1) componentImported
Gene namesi
Name:sucAImported
Ordered Locus Names:LBJ_2123Imported
OrganismiLeptospira borgpetersenii serovar Hardjo-bovis (strain JB197)Imported
Taxonomic identifieri355277 [NCBI]
Taxonomic lineageiBacteriaSpirochaetesSpirochaetalesLeptospiraceaeLeptospira
ProteomesiUP000000656: Chromosome 1

Interactioni

Protein-protein interaction databases

STRINGi355277.LBJ_2123.

Structurei

3D structure databases

ProteinModelPortaliQ04R53.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04R53-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVEKLMALY GENGVLLEEL YNQYKLNPET VDKEWKSFFQ EVDTNGFANG
60 70 80 90 100
NGGGYSNGKS AVATSFTDAQ AGSIREMGII NLLNAYRRQG HLAAKLDPLG
110 120 130 140 150
IQKPNRTFID SKLHSISPAD LETVVDSDTL GRVKLAEIVD LYEKVYCNTI
160 170 180 190 200
GAEHFYLVDD VEREWLQKKM ESPEFLAPLP KSIKLRLFEK LFQADYFETF
210 220 230 240 250
LAKKYVGKKR FSLEGGESFI PLLDTIVEEA GHHLMDGLVI GMAHRGRLNV
260 270 280 290 300
LVNIIEKPAS LIFAEFEEKT DRDNLSYADV KYHLGYSNSR MTTAGKEVKL
310 320 330 340 350
SLMFNPSHLE CVGPVVTGSV RARQELIGNK DRTKYMPILI HGDAAFAGQG
360 370 380 390 400
VVAETLNLMN LEGYTTGGTF HIVVNNQIGF TTLPDESRST LYATDLAKGF
410 420 430 440 450
QIPIIHVNGD DPEAVYRVVK LGMEYRQKFK KDFIIDLVCY RRLGHNETDE
460 470 480 490 500
PAFTQPKMYA TIKNHPPTVK LYEKRLVEEG DIQQEDIDFI KNGSMHGLED
510 520 530 540 550
SFQRAKEQDV KIRVDTMQGV WSKFSKMSLD SEPATKLLKE QMHGIVQALT
560 570 580 590 600
GVPRDFTPNS KLVKLLQSRK EMAEGKIPVD WGFAEALSFG SILESGFRIR
610 620 630 640 650
LSGQDSQRGT FSHRHAVLVD TNTNEKYIPL NHISPKQAKA EIINSSLSEF
660 670 680 690 700
SVLGFEYGYS LSDPNALVIW EAQFGDFANS AQVIFDQFIS SSEVKWQRLS
710 720 730 740 750
GLTMLLPHGY EGQGPEHSSA RLERFLQLCA LNNMQVCNLT TAAQYFHLLR
760 770 780 790 800
RQMLRNYRKP LVIVTPKSLL RFPASLSPVE DILQGAFKEI LVDDSGLKSD
810 820 830 840 850
KIEKVIFSAG KVYYDLVKYR DENKIQNVVF VRVEQIYPFP AKEIEGALKK
860 870 880 890 900
FKNAKSFVWC QEEPKNQGAW FFVRERIEDL LPSNVRLSYA GRHESPSPAA
910 920
GHMKLHLQEQ DQLVLEAFQA
Length:920
Mass (Da):104,018
Last modified:November 14, 2006 - v1
Checksum:iCAFFAB9D6C7D2C73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000350 Genomic DNA. Translation: ABJ76617.1.
RefSeqiYP_801375.1. NC_008510.1.

Genome annotation databases

EnsemblBacteriaiABJ76617; ABJ76617; LBJ_2123.
GeneIDi4410249.
KEGGilbj:LBJ_2123.
PATRICi22360036. VBILepBor13265_2722.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000350 Genomic DNA. Translation: ABJ76617.1.
RefSeqiYP_801375.1. NC_008510.1.

3D structure databases

ProteinModelPortaliQ04R53.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi355277.LBJ_2123.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABJ76617; ABJ76617; LBJ_2123.
GeneIDi4410249.
KEGGilbj:LBJ_2123.
PATRICi22360036. VBILepBor13265_2722.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259588.
KOiK00164.
OMAiQNQGAWF.
OrthoDBiEOG6V1M1F.

Enzyme and pathway databases

BioCyciLBOR355277:GHYM-2097-MONOMER.

Family and domain databases

Gene3Di3.40.50.970. 2 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: JB197Imported.

Entry informationi

Entry nameiQ04R53_LEPBJ
AccessioniPrimary (citable) accession number: Q04R53
Entry historyi
Integrated into UniProtKB/TrEMBL: November 14, 2006
Last sequence update: November 14, 2006
Last modified: January 7, 2015
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.