Q04LG7 (Q04LG7_STRP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Cation-transporting ATPase, E1-E2 family protein EMBL ABJ55473.1
EC=3.6.3.4 EMBL ABJ55473.1

Gene names

Ordered Locus Names:

SPD_0635 EMBL ABJ55473.1

Organism

Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) [Complete proteome] [HAMAP] EMBL ABJ55473.1

Taxonomic identifier

373153 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus › Streptococcus pneumoniae

Protein attributes

Sequence length	747 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane RuleBase RU000653
Ligand	ATP-binding RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase RuleBase RU000653 EMBL ABJ55473.1
Technical term	3D-structure PDB 4F2F Complete proteome
Gene Ontology (GO)
Biological_process	copper ion export Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW copper-exporting ATPase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q04LG7 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: D41F5DEF2E8DBD7F	FASTA	747	80,467
	10 20 30 40 50 60 MTEIVKASLE NGIQKIRIQA EKGYHPAHIQ LQKGIPAEIT FHRATPSNCY KEILFEEEGI 70 80 90 100 110 120 LEPIGVDEEK VIRFTPQELG RHEFSCGMKM QKGSYTVVEK TRKSLSLLQR FWITSIFTVP 130 140 150 160 170 180 LVILMIGMLT GSISHQVMHW GTFLATTPIM LVAGKPYIQS AWASFKKHNA NMDTLVALGT 190 200 210 220 230 240 LVAYFYSLVA LFAGLPVYFE SAGFILFFVL LGAVFEEKMR KNTSQAVEKL LDLQAKTAEV 250 260 270 280 290 300 LSDDSYVQVP LEQVKVGDLI RVRPGEKIAV DGVVVEGVSS IDESMVTGES LPVDKTVGDT 310 320 330 340 350 360 VIGSTINHSG TLVFRAEKVG SETVLAQIVD FVKKAQTSRA PIQDLTDKIS GIFVPVVVIL 370 380 390 400 410 420 GIMTFWVWFV LLRDSVVVLG ASFVSSLLYG VAVLIIACPC ALGLATPTAL MVGTGRSAKM 430 440 450 460 470 480 GVLLKNGTVL QEIQKVQTLV FDKTGTLTEG KPVVTDIIGD EVEVFGLAAS LEDASQHPLA 490 500 510 520 530 540 EAIVKRASEA GLEFQTVENF QALHGKGVSG RINGKQVLLG NAKMLDGMDI SNTYQDKLEE 550 560 570 580 590 600 LEKEAKTVVF LAVDNEIKGL LALQDIPKEN AKLAISQLKK RGLRTVMLTG DNAGVARAIA 610 620 630 640 650 660 DQIGIEEVIA GVLPEEKAHE IHKLQAAGKV AFVGDGINDA PALSVADVGI AMGAGTDIAI 670 680 690 700 710 720 ESADLVLTTN NLLGVVRAFD MSKKTFHRIL LNLFWAFIYN VVGIPIAAGV FSGVGLALNP 730 740 ELAGLAMAFS SVSVLTSSLL LNFSKID

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6." Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E. J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: D39 / NCTC 7466.
[2]	"A new structural paradigm in copper resistance in Streptococcus pneumoniae." Fu Y., Tsui H.C., Bruce K.E., Sham L.T., Higgins K.A., Lisher J.P., Kazmierczak K.M., Maroney M.J., Dann C.E., Winkler M.E., Giedroc D.P. Nat. Chem. Biol. 9:177-183(2013) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.50 ANGSTROMS) OF 1-99.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

CP000410 Genomic DNA. Translation: ABJ55473.1.

RefSeq

YP_816131.1. NC_008533.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4F2F	X-ray	1.50	A	1-99	[»]

ProteinModelPortal

Q04LG7.

ModBase

Search...

Protein-protein interaction databases

STRING

373153.SPD_0635.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

ABJ55473; ABJ55473; SPD_0635.

GeneID

4441853.

KEGG

spd:SPD_0635.

PATRIC

19682360. VBIStrPne27904_0720.

Organism-specific databases

CMR

Search...

Phylogenomic databases

eggNOG

COG2217.

HOGENOM

HOG000250397.

KO

K01533.

OMA

IHKLQQS.

ProtClustDB

CLSK883985.

Family and domain databases

Gene3D

2.70.150.10. 1 hit.
3.40.1110.10. 1 hit.
3.40.50.1000. 2 hits.

InterPro

IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR027256. Cation_transp_P-typ_ATPase_IB.
IPR001757. Cation_transp_P_typ_ATPase.
IPR027183. Cu-transptr_ATPase.
IPR023214. HAD-like_dom.
[Graphical view]

PANTHER

PTHR24093. PTHR24093. 1 hit.
PTHR24093:SF50. PTHR24093:SF50. 1 hit.

Pfam

PF00122. E1-E2_ATPase. 1 hit.
PF00702. Hydrolase. 1 hit.
[Graphical view]

PRINTS

PR00119. CATATPASE.

SUPFAM

SSF56784. HAD-like_dom. 1 hit.

TIGRFAMs

TIGR01525. ATPase-IB_hvy. 1 hit.
TIGR01494. ATPase_P-type. 1 hit.

PROSITE

PS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q04LG7_STRP2

Accession

Primary (citable) accession number: Q04LG7

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)