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Q04KG5 (GLGA_STRP2) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glycogen synthase
EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:SPD_1008
OrganismStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) [Complete proteome] [HAMAP]
Taxonomic identifier373153 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacilli › Lactobacillales › Streptococcaceae › Streptococcus ›

Protein attributes

Sequence length477 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 477477Glycogen synthase HAMAP-Rule MF_00484
PRO_1000014384

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q04KG5 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: D6F2D4911B7091AC

FASTA47754,168
        10         20         30         40         50         60 
MKILFVAAEG APFSKTGGLG DVIGALPKSL VKAGHEVAVI LPYYDMVEAK FGNQIEDVLH 

        70         80         90        100        110        120 
FEVSVGWRRQ YCGIKKTVLN GVTFYFIDNQ YYFFRGHVYG DFDDGERFAF FQLAAIEAME 

       130        140        150        160        170        180 
RIDFIPDLLH VHDYHTAMIP FLLKEKYRWI QAYEDIETVL TIHNLEFQGQ FSEGMLGDLF 

       190        200        210        220        230        240 
GVGFERYADG TLRWNNCLNW MKAGILYANR VSTVSPSYAH EIMTSQFGCN LDHILKMESG 

       250        260        270        280        290        300 
KVSGIVNGID ADLYNPQTDA LLDYHFNQED LSGKAKNKAK LQERVGLPVR ADVPLVGIVS 

       310        320        330        340        350        360 
RLTRQKGFDV VVESLHHILQ EDVQIVLLGT GDPAFEGAFS WFAQIYPDKL STNITFDVKL 

       370        380        390        400        410        420 
AQEIYAACDL FLMPSRFEPC GLSQMMAMRY GTLPLVHEVG GLRDTVRAFN PIEGSGTGFS 

       430        440        450        460        470 
FDNLSPYWLN WTFQTALDLY RNHPDIWRNL QKQAMESDFS WDTACKSYLD LYHSLVN

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References

[1]"Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6."
Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E.
J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: D39 / NCTC 7466.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000410 Genomic DNA. Translation: ABJ54779.1.
RefSeqYP_816483.1. NC_008533.1.

3D structure databases

ProteinModelPortalQ04KG5.
ModBaseSearch...

Protein-protein interaction databases

STRING373153.SPD_1008.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ54779; ABJ54779; SPD_1008.
GeneID4443012.
KEGGspd:SPD_1008.
PATRIC19683182. VBIStrPne27904_1126.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294940.
KOK00703.
OMAADVIMVP.
ProtClustDBPRK00654.

Enzyme and pathway databases

UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_STRP2
AccessionPrimary (citable) accession number: Q04KG5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: May 1, 2013
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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