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Protein

tRNA pseudouridine synthase B

Gene

truB

Organism
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.UniRule annotation

Catalytic activityi

tRNA uridine(55) = tRNA pseudouridine(55).UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei38NucleophileUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomerase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
tRNA pseudouridine synthase BUniRule annotation (EC:5.4.99.25UniRule annotation)
Alternative name(s):
tRNA pseudouridine(55) synthaseUniRule annotation
Short name:
Psi55 synthaseUniRule annotation
tRNA pseudouridylate synthaseUniRule annotation
tRNA-uridine isomeraseUniRule annotation
Gene namesi
Name:truBUniRule annotation
Ordered Locus Names:SPD_1070
OrganismiStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Taxonomic identifieri373153 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000001452 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000846961 – 292tRNA pseudouridine synthase BAdd BLAST292

Proteomic databases

PRIDEiQ04KA7

Interactioni

Protein-protein interaction databases

STRINGi373153.SPD_1070

Structurei

3D structure databases

ProteinModelPortaliQ04KA7
SMRiQ04KA7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105D0T Bacteria
COG0130 LUCA
HOGENOMiHOG000231225
KOiK03177
OMAiVDCSKGT

Family and domain databases

HAMAPiMF_01080 TruB_bact, 1 hit
InterProiView protein in InterPro
IPR020103 PsdUridine_synth_cat_dom_sf
IPR002501 PsdUridine_synth_N
IPR014780 tRNA_psdUridine_synth_TruB
IPR032819 TruB_C
PANTHERiPTHR13767 PTHR13767, 1 hit
PfamiView protein in Pfam
PF16198 TruB_C_2, 1 hit
PF01509 TruB_N, 1 hit
SUPFAMiSSF55120 SSF55120, 1 hit
TIGRFAMsiTIGR00431 TruB, 1 hit

Sequencei

Sequence statusi: Complete.

Q04KA7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNGIINLKKE AGMTSHDAVF KLRKILGTKK IGHGGTLDPD VVGVLPIAVG
60 70 80 90 100
KATRMVEFMQ DEGKIYEGEI ILGYSTTTED ASGEVVAETP VLSSLDEKLV
110 120 130 140 150
DEAIASLTGP ITQIPPMYSA VKVNGRKLYE YARAGQEVER PERQVIIYQF
160 170 180 190 200
ERTSPISYDG QLARFTFRVK CSKGTYIRTL SVDLGEKLGY AAHMSHLTRT
210 220 230 240 250
SAAGLQLEDA LALEEIAEKV EAGQLDFLHP LEIGTGDLVK VFLTPEEATE
260 270 280 290
VRFGRFIELD QTDKELAAFE DDKLLAILEK RGNLYKPRKV FS
Length:292
Mass (Da):32,256
Last modified:November 14, 2006 - v1
Checksum:i2716D45FFC2E145E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000410 Genomic DNA Translation: ABJ54024.1
RefSeqiWP_001013236.1, NC_008533.1

Genome annotation databases

EnsemblBacteriaiABJ54024; ABJ54024; SPD_1070
KEGGispd:SPD_1070

Similar proteinsi

Entry informationi

Entry nameiTRUB_STRP2
AccessioniPrimary (citable) accession number: Q04KA7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: November 14, 2006
Last modified: May 23, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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