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Q04JI4

- WHIA_STRP2

UniProt

Q04JI4 - WHIA_STRP2

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Protein
Putative sporulation transcription regulator WhiA
Gene
whiA, SPD_1394
Organism
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

May be required for sporulation By similarity.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi272 – 30332H-T-H motif Reviewed prediction
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. endonuclease activity Source: InterPro

GO - Biological processi

  1. regulation of sporulation Source: UniProtKB-HAMAP
  2. regulation of transcription, DNA-templated Source: UniProtKB-KW
  3. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Enzyme and pathway databases

BioCyciSPNE373153:GIX6-1394-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative sporulation transcription regulator WhiA
Gene namesi
Name:whiA
Ordered Locus Names:SPD_1394
OrganismiStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Taxonomic identifieri373153 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001452: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 303303Putative sporulation transcription regulator WhiAUniRule annotation
PRO_0000376581Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi373153.SPD_1394.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG1481.
HOGENOMiHOG000040187.
KOiK09762.
OMAiHKFMLDA.
OrthoDBiEOG68WR87.

Family and domain databases

Gene3Di3.10.28.10. 1 hit.
HAMAPiMF_01420. HTH_type_WhiA.
InterProiIPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view]
PfamiPF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view]
SUPFAMiSSF55608. SSF55608. 1 hit.
TIGRFAMsiTIGR00647. MG103. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04JI4-1 [UniParc]FASTAAdd to Basket

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MSFTVAVKEE ILGQHHLSWH ELSAIIKMSG SIGLSTSGLT LSVVTENAKL    50
ARHLYESFLH FYEIKSEIRH HQRSNLRKNR VYTVFTDEKV QDLLSDLHLA 100
DSFFGLETGI DEAILSDEEA GRAYLCGAFL ANGSIRDPES GKYQLEISSV 150
YLDHAQGIAS LLQQFLLDAK VLERKKGAVT YLQRAEDIMD FLIVIGAMQA 200
RDDFERVKIL RETRNDLNRA NNAETANIAR TVSASMKTIN NISKIKDIMG 250
LENLPVDLQE VAQLRIQHPD YSIQQLADSL STPLTKSGVN HRLRKINKIA 300
DEL 303
Length:303
Mass (Da):34,092
Last modified:November 14, 2006 - v1
Checksum:iAF33FFE6D2578400
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000410 Genomic DNA. Translation: ABJ53810.1.
RefSeqiYP_816854.1. NC_008533.1.

Genome annotation databases

EnsemblBacteriaiABJ53810; ABJ53810; SPD_1394.
GeneIDi4442995.
KEGGispd:SPD_1394.
PATRICi19684020. VBIStrPne27904_1543.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000410 Genomic DNA. Translation: ABJ53810.1 .
RefSeqi YP_816854.1. NC_008533.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 373153.SPD_1394.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ53810 ; ABJ53810 ; SPD_1394 .
GeneIDi 4442995.
KEGGi spd:SPD_1394.
PATRICi 19684020. VBIStrPne27904_1543.

Phylogenomic databases

eggNOGi COG1481.
HOGENOMi HOG000040187.
KOi K09762.
OMAi HKFMLDA.
OrthoDBi EOG68WR87.

Enzyme and pathway databases

BioCyci SPNE373153:GIX6-1394-MONOMER.

Family and domain databases

Gene3Di 3.10.28.10. 1 hit.
HAMAPi MF_01420. HTH_type_WhiA.
InterProi IPR027434. Homing_endonucl.
IPR018478. Sporu_reg_WhiA_N_dom.
IPR003802. Sporulation_regulator_WhiA.
IPR023054. Sporulation_regulator_WhiA_C.
[Graphical view ]
Pfami PF02650. HTH_WhiA. 1 hit.
PF10298. WhiA_N. 1 hit.
[Graphical view ]
SUPFAMi SSF55608. SSF55608. 1 hit.
TIGRFAMsi TIGR00647. MG103. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6."
    Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E.
    J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D39 / NCTC 7466.

Entry informationi

Entry nameiWHIA_STRP2
AccessioniPrimary (citable) accession number: Q04JI4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: November 14, 2006
Last modified: September 3, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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