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Q04J78

- Q04J78_STRP2

UniProt

Q04J78 - Q04J78_STRP2

Protein
Submitted name:

Sialidase A

Gene

nanA

Organism
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 55 (01 Oct 2014)
      Sequence version 1 (14 Nov 2006)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. exo-alpha-(2->3)-sialidase activity Source: UniProtKB-EC
    2. exo-alpha-(2->6)-sialidase activity Source: UniProtKB-EC
    3. exo-alpha-(2->8)-sialidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. carbohydrate metabolic process Source: InterPro

    Keywords - Molecular functioni

    GlycosidaseImported, Hydrolase

    Enzyme and pathway databases

    BioCyciSPNE373153:GIX6-1504-MONOMER.

    Protein family/group databases

    CAZyiCBM40. Carbohydrate-Binding Module Family 40.
    GH33. Glycoside Hydrolase Family 33.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Sialidase AImported (EC:3.2.1.18Imported)
    Gene namesi
    Name:nanAImported
    Ordered Locus Names:SPD_1504Imported
    OrganismiStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)Imported
    Taxonomic identifieri373153 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
    ProteomesiUP000001452: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi373153.SPD_1504.

    Structurei

    3D structure databases

    ProteinModelPortaliQ04J78.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG4409.
    HOGENOMiHOG000284737.
    KOiK01186.
    OMAiGGPKREN.
    OrthoDBiEOG61CM2G.

    Family and domain databases

    Gene3Di2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProiIPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view]
    PANTHERiPTHR10628. PTHR10628. 1 hit.
    PfamiPF02973. Sialidase. 1 hit.
    [Graphical view]
    SMARTiSM00282. LamG. 1 hit.
    [Graphical view]
    SUPFAMiSSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsiTIGR01167. LPXTG_anchor. 1 hit.
    PROSITEiPS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04J78-1 [UniParc]FASTAAdd to Basket

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    MIVGAVVFGT SPVLAQEGAS EQPLANETQL SGESSTLTDT EKSQPSSETE    50
    LSGNKQEQER KDKQEEKIPR DYYARDLENV ETVIEKEDVE TNASNGQRVD 100
    LSSELDKLKK LENATVHMEF KPDAKAPAFY NLFSVSSATK KDEYFTMAVY 150
    NNTATLEGRG SDGKQFYNNY NDAPLKVKPG QWNSVTFTVE KPTAELPKGR 200
    VRLYVNGVLS RTSLRSGNFI KDMPDVTHVQ IGATKRANNT VWGSNLQIRN 250
    LTVYNRALTP EEVQKRSQLF KRSDLEKKLP EGAALTEKTD IFESGRNGKP 300
    NKDGIKSYRI PALLKTDKGT LIAGADERRL HSSDWGDIGM VIRRSEDNGK 350
    TWGDRVTITN LRDNPKASDP SIGSPVNIDM VLVQDPETKR IFSIYDMFPE 400
    GKGIFGMSSQ KEEAYKKIDG KTYQILYREG EKGAYTIREN GTVYTPDGKA 450
    TDYRVVVDPV KPAYSDKGDL YKGNQLLGNI YFTTNKTSPF RIAKDSYLWM 500
    SYSDDDGKTW SAPQDITPMV KADWMKFLGV GPGTGIVLRN GPHKGRILIP 550
    VYTTNNVSHL NGSQSSRIIY SDDHGKTWHA GEAVNDNRQV DGQKIHSSTM 600
    NNRRAQNTES TVVQLNNGDV KLFMRGLTGD LQVATSKDGG VTWEKDIKRY 650
    PQVKDVYVQM SAIHTMHEGK EYIILSNAGG PKRENGMVHL ARVEENGELT 700
    WLKHNPIQKG EFAYNSLQEL GNGEYGILYE HTEKGQNAYT LSFRKFNWDF 750
    LSKDLISPTE AKVKRTREMG KGVIGLEFDS EVLVNKAPTL QLANGKTARF 800
    MTQYDTKTLL FTVDSEDMGQ KVTGLAEGAI ESMHNLPVSV AGTKLSNGMN 850
    GSEAAVHEVP EYTGPLGTSG EEPAPTVEKP EYTGPLGTSG EEPAPTVEKP 900
    EYTGPLGTAG EEAAPTVEKP EFTGGVNGTE PAVHEIAEYK GSDSLVTLTT 950
    KEDYTYKAPL AQQALPETGN KESDLLASLG LTAFFLGLFT LGKKREQ 997
    Length:997
    Mass (Da):110,193
    Last modified:November 14, 2006 - v1
    Checksum:i92556718476CC54C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000410 Genomic DNA. Translation: ABJ55437.1.
    RefSeqiYP_816960.1. NC_008533.1.

    Genome annotation databases

    EnsemblBacteriaiABJ55437; ABJ55437; SPD_1504.
    GeneIDi4442379.
    KEGGispd:SPD_1504.
    PATRICi19684263. VBIStrPne27904_1663.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000410 Genomic DNA. Translation: ABJ55437.1 .
    RefSeqi YP_816960.1. NC_008533.1.

    3D structure databases

    ProteinModelPortali Q04J78.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 373153.SPD_1504.

    Protein family/group databases

    CAZyi CBM40. Carbohydrate-Binding Module Family 40.
    GH33. Glycoside Hydrolase Family 33.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABJ55437 ; ABJ55437 ; SPD_1504 .
    GeneIDi 4442379.
    KEGGi spd:SPD_1504.
    PATRICi 19684263. VBIStrPne27904_1663.

    Phylogenomic databases

    eggNOGi COG4409.
    HOGENOMi HOG000284737.
    KOi K01186.
    OMAi GGPKREN.
    OrthoDBi EOG61CM2G.

    Enzyme and pathway databases

    BioCyci SPNE373153:GIX6-1504-MONOMER.

    Family and domain databases

    Gene3Di 2.120.10.10. 2 hits.
    2.60.120.200. 1 hit.
    InterProi IPR008985. ConA-like_lec_gl_sf.
    IPR013320. ConA-like_subgrp.
    IPR004124. Glyco_hydro_33_N.
    IPR001791. Laminin_G.
    IPR019931. LPXTG_anchor.
    IPR026856. Sialidase_fam.
    IPR011040. Sialidases.
    [Graphical view ]
    PANTHERi PTHR10628. PTHR10628. 1 hit.
    Pfami PF02973. Sialidase. 1 hit.
    [Graphical view ]
    SMARTi SM00282. LamG. 1 hit.
    [Graphical view ]
    SUPFAMi SSF49899. SSF49899. 1 hit.
    SSF50939. SSF50939. 2 hits.
    TIGRFAMsi TIGR01167. LPXTG_anchor. 1 hit.
    PROSITEi PS50847. GRAM_POS_ANCHORING. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6."
      Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E.
      J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: D39 / NCTC 7466Imported.

    Entry informationi

    Entry nameiQ04J78_STRP2
    AccessioniPrimary (citable) accession number: Q04J78
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 14, 2006
    Last sequence update: November 14, 2006
    Last modified: October 1, 2014
    This is version 55 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3