Q04J78 (Q04J78_STRP2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Sialidase A EMBL ABJ55437.1
EC=3.2.1.18 EMBL ABJ55437.1

Gene names

Name:	nanA EMBL ABJ55437.1
Ordered Locus Names:	SPD_1504

Organism

Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) [Complete proteome] [HAMAP] EMBL ABJ55437.1

Taxonomic identifier

373153 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Streptococcaceae › Streptococcus

Protein attributes

Sequence length	997 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Cellular component	Secreted SAAS SAAS019931
Molecular function	Glycosidase EMBL ABJ55437.1 Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cell surface Inferred from electronic annotation. Source: InterPro
Molecular function	exo-alpha-(2->3)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->6)-sialidase activity Inferred from electronic annotation. Source: EC exo-alpha-(2->8)-sialidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q04J78 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 92556718476CC54C	FASTA	997	110,193
	10 20 30 40 50 60 MIVGAVVFGT SPVLAQEGAS EQPLANETQL SGESSTLTDT EKSQPSSETE LSGNKQEQER 70 80 90 100 110 120 KDKQEEKIPR DYYARDLENV ETVIEKEDVE TNASNGQRVD LSSELDKLKK LENATVHMEF 130 140 150 160 170 180 KPDAKAPAFY NLFSVSSATK KDEYFTMAVY NNTATLEGRG SDGKQFYNNY NDAPLKVKPG 190 200 210 220 230 240 QWNSVTFTVE KPTAELPKGR VRLYVNGVLS RTSLRSGNFI KDMPDVTHVQ IGATKRANNT 250 260 270 280 290 300 VWGSNLQIRN LTVYNRALTP EEVQKRSQLF KRSDLEKKLP EGAALTEKTD IFESGRNGKP 310 320 330 340 350 360 NKDGIKSYRI PALLKTDKGT LIAGADERRL HSSDWGDIGM VIRRSEDNGK TWGDRVTITN 370 380 390 400 410 420 LRDNPKASDP SIGSPVNIDM VLVQDPETKR IFSIYDMFPE GKGIFGMSSQ KEEAYKKIDG 430 440 450 460 470 480 KTYQILYREG EKGAYTIREN GTVYTPDGKA TDYRVVVDPV KPAYSDKGDL YKGNQLLGNI 490 500 510 520 530 540 YFTTNKTSPF RIAKDSYLWM SYSDDDGKTW SAPQDITPMV KADWMKFLGV GPGTGIVLRN 550 560 570 580 590 600 GPHKGRILIP VYTTNNVSHL NGSQSSRIIY SDDHGKTWHA GEAVNDNRQV DGQKIHSSTM 610 620 630 640 650 660 NNRRAQNTES TVVQLNNGDV KLFMRGLTGD LQVATSKDGG VTWEKDIKRY PQVKDVYVQM 670 680 690 700 710 720 SAIHTMHEGK EYIILSNAGG PKRENGMVHL ARVEENGELT WLKHNPIQKG EFAYNSLQEL 730 740 750 760 770 780 GNGEYGILYE HTEKGQNAYT LSFRKFNWDF LSKDLISPTE AKVKRTREMG KGVIGLEFDS 790 800 810 820 830 840 EVLVNKAPTL QLANGKTARF MTQYDTKTLL FTVDSEDMGQ KVTGLAEGAI ESMHNLPVSV 850 860 870 880 890 900 AGTKLSNGMN GSEAAVHEVP EYTGPLGTSG EEPAPTVEKP EYTGPLGTSG EEPAPTVEKP 910 920 930 940 950 960 EYTGPLGTAG EEAAPTVEKP EFTGGVNGTE PAVHEIAEYK GSDSLVTLTT KEDYTYKAPL 970 980 990 AQQALPETGN KESDLLASLG LTAFFLGLFT LGKKREQ

References

[1]

"Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6." Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E. J. Bacteriol. 189:38-51(2007) [PubMed: 17041037] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000410 Genomic DNA. Translation: ABJ55437.1.
RefSeq	YP_816960.1. NC_008533.1.
3D structure databases
ProteinModelPortal	Q04J78.
ModBase	Search...
Protein-protein interaction databases
STRING	Q04J78.
Protein family/group databases
CAZy	CBM40. Carbohydrate-Binding Module Family 40. GH33. Glycoside Hydrolase Family 33.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBSTRT00000020686; EBSTRP00000019926; EBSTRG00000020686.
GeneID	4442379.
GenomeReviews	Gene locus SPD_1504 in contig CP000410_GR.
KEGG	spd:SPD_1504.
PATRIC	19684263. VBIStrPne27904_1663.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG4409.
GeneTree	EBGT00050000026665.
HOGENOM	HBG702052.
OMA	DWMKFLG.
ProtClustDB	CLSK560471.
Family and domain databases
InterPro	IPR002860. BNR_rpt. IPR008985. ConA-like_lec_gl. IPR013320. ConA-like_subgrp. IPR004124. Glyco_hydro_33_N. IPR001791. Laminin_G. IPR019931. LPXTG-motif_cell_wall_anchor. IPR011040. Neuraminidase. IPR001899. Surface_protein_Gram_pos_cocci. IPR023364. Trans_sialidase_dom3. [Graphical view]
Gene3D	G3DSA:2.60.120.200. ConA_like_subgrp. 1 hit. G3DSA:2.40.220.10. G3DSA:2.40.220.10. 1 hit. G3DSA:2.120.10.10. Neuraminidase. 2 hits.
KO	K01186.
Pfam	PF02012. BNR. 4 hits. PF02973. Sialidase. 1 hit. [Graphical view]
SMART	SM00282. LamG. 1 hit. [Graphical view]
SUPFAM	SSF49899. ConA_like_lec_gl. 1 hit. SSF50939. Sialidase. 1 hit.
TIGRFAMs	TIGR01167. LPXTG_anchor. 1 hit.
PROSITE	PS50847. GRAM_POS_ANCHORING. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q04J78_STRP2

Accession

Primary (citable) accession number: Q04J78

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)