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Q04IA2 (G6PI_STRP2) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 46. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:SPD_1897
OrganismStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) [Complete proteome] [HAMAP]
Taxonomic identifier373153 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 449449Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_1000014026

Sites

Active site2911Proton donor By similarity
Active site3121 By similarity
Active site4261 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q04IA2 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 563518A955D0C1E8

FASTA44949,878
        10         20         30         40         50         60 
MSHIKFDYSK VLDKFVAPHE VEYMQSQVTA ADELIRKGTG AGSDFLGWLD LPEKYDREEF 

        70         80         90        100        110        120 
DRILKAAEQI KSDSDVLVVI GIGGSYLGAK AAIDFLNHHF ANLQTKEERK APQILYAGNS 

       130        140        150        160        170        180 
ISSTYLADLV EYVADKDFSV NVISKSGTTT EPAIAFRVFK ELLVKKYGQE EANKRIYATT 

       190        200        210        220        230        240 
DRQKGAVKVE ADANGWGTFV VPDDIGGRFS VLTAVGLLPI AASGADIKAL MEGANAARKD 

       250        260        270        280        290        300 
YTSDKISENE AYQYAAVRNI LYRKGYATEI LVNYEPSLQY FSEWWKQLAG ESEGKDQKGI 

       310        320        330        340        350        360 
YPTSANFSTD LHSLGQFIQE GTRIMFETVV RVDKPRKNVL IPTLEEDLDG LGYLQGKDVD 

       370        380        390        400        410        420 
FVNKKATDGV LLAHTDGDVP NMYVTLPEQD AFTLGYTIYF FELAIALSGY LNAINPFDQP 

       430        440 
GVEAYKRNMF ALLGKPGFEE LSKELNARL 

« Hide

References

[1]"Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6."
Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E.
J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: D39 / NCTC 7466.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000410 Genomic DNA. Translation: ABJ54906.1.
RefSeqYP_817286.1. NC_008533.1.

3D structure databases

ProteinModelPortalQ04IA2.
SMRQ04IA2. Positions 3-449.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING373153.SPD_1897.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ54906; ABJ54906; SPD_1897.
GeneID4442387.
KEGGspd:SPD_1897.
PATRIC19685116. VBIStrPne27904_2038.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000100403.
KOK01810.
OMAEPSLHFV.
OrthoDBEOG64R61J.
ProtClustDBPRK14097.

Enzyme and pathway databases

BioCycSPNE373153:GIX6-1897-MONOMER.
UniPathwayUPA00109; UER00181.
UPA00138.

Family and domain databases

HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_STRP2
AccessionPrimary (citable) accession number: Q04IA2
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 46 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways