SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q04I94

- SYR_STRP2

UniProt

Q04I94 - SYR_STRP2

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Arginine--tRNA ligase
Gene
argS, SPD_1905
Organism
Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSPNE373153:GIX6-1905-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:SPD_1905
OrganismiStreptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466)
Taxonomic identifieri373153 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
ProteomesiUP000001452: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 563563Arginine--tRNA ligaseUniRule annotation
PRO_1000018127Add
BLAST

Interactioni

Subunit structurei

Monomer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi373153.SPD_1905.

Structurei

3D structure databases

ProteinModelPortaliQ04I94.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi121 – 13111"HIGH" regionUniRule annotation
Add
BLAST

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247211.
KOiK01887.
OMAiYVKFHDE.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04I94-1 [UniParc]FASTAAdd to Basket

« Hide

MNTKELIASE LSSIIDSLDQ EAILKLLETP KNSEMGDIAF PAFSLAKVER    50
KAPQMIAAEL AEKMNSQAFE KVVATGPYVN FFLDKSAISA QVLQAVTTEK 100
EHYADQNIGK QENVVIDMSS PNIAKPFSIG HLRSTVIGDS LSHIFQKIGY 150
QTVKVNHLGD WGKQFGMLIV AYKKWGDEEA VKAHPIDELL KLYVRINAEA 200
ENDPSLDEEA REWFRKLENG DEEALALWQW FRDESLVEFN RLYNELKVEF 250
DSYNGEAFYN DKMDAVVDIL SEKGLLLESE GAQVVNLEKY GIEHPALIKK 300
SDGATLYITR DLAAALYRKN EYQFAKSIYV VGQEQSAHFK QLKAVLQEMG 350
YDWSDDITHV PFGLVTKEGK KLSTRKGNVI LLEPTVAEAV SRAKVQIEAK 400
NPELENKDQV AHAVGVGAIK FYDLKTDRTN GYDFDLEAMV SFEGETGPYV 450
QYAYARIQSI LRKADFKPET AGNYSLNDTE SWEIIKLIQD FPRIINRAAD 500
NFEPSIIAKF AISLAQSFNK YYAHTRILDE SPERDSRLAL SYATAVVLKE 550
ALRLLGVEAP EKM 563
Length:563
Mass (Da):63,458
Last modified:November 14, 2006 - v1
Checksum:i1FBF18752CC04183
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000410 Genomic DNA. Translation: ABJ54835.1.
RefSeqiYP_817294.1. NC_008533.1.

Genome annotation databases

EnsemblBacteriaiABJ54835; ABJ54835; SPD_1905.
GeneIDi4441042.
KEGGispd:SPD_1905.
PATRICi19685132. VBIStrPne27904_2046.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000410 Genomic DNA. Translation: ABJ54835.1 .
RefSeqi YP_817294.1. NC_008533.1.

3D structure databases

ProteinModelPortali Q04I94.
ModBasei Search...

Protein-protein interaction databases

STRINGi 373153.SPD_1905.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ54835 ; ABJ54835 ; SPD_1905 .
GeneIDi 4441042.
KEGGi spd:SPD_1905.
PATRICi 19685132. VBIStrPne27904_2046.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247211.
KOi K01887.
OMAi YVKFHDE.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci SPNE373153:GIX6-1905-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Avery's virulent serotype 2 strain D39 of Streptococcus pneumoniae and comparison with that of unencapsulated laboratory strain R6."
    Lanie J.A., Ng W.-L., Kazmierczak K.M., Andrzejewski T.M., Davidsen T.M., Wayne K.J., Tettelin H., Glass J.I., Winkler M.E.
    J. Bacteriol. 189:38-51(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: D39 / NCTC 7466.

Entry informationi

Entry nameiSYR_STRP2
AccessioniPrimary (citable) accession number: Q04I94
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: May 14, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi