ID   ADEC1_OENOB             Reviewed;         553 AA.
AC   Q04HC1;
DT   26-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 1.
DT   16-JUN-2009, entry version 17.
DE   RecName: Full=Adenine deaminase 1;
DE            Short=Adenase 1;
DE            Short=Adenine aminase 1;
DE            EC=3.5.4.2;
GN   Name=ade1; OrderedLocusNames=OEOE_0158;
OS   Oenococcus oeni (strain BAA-331 / PSU-1).
OC   Bacteria; Firmicutes; Lactobacillales; Oenococcus.
OX   NCBI_TaxID=203123;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=17030793; DOI=10.1073/pnas.0607117103;
RA   Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B.,
RA   Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N.,
RA   Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K.,
RA   Goodstein D.M., Hawkins T., Plengvidhya V., Welker D., Hughes J.,
RA   Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B.,
RA   Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E.,
RA   Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C.,
RA   Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J.,
RA   Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S.,
RA   Weimer B.C., Mills D.A.;
RT   "Comparative genomics of the lactic acid bacteria.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006).
CC   -!- CATALYTIC ACTIVITY: Adenine + H(2)O = hypoxanthine + NH(3).
CC   -!- COFACTOR: Manganese (By similarity).
CC   -!- SIMILARITY: Belongs to the adenine deaminase family.
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DR   EMBL; CP000411; ABJ56151.1; -; Genomic_DNA.
DR   RefSeq; YP_809816.1; -.
DR   GeneID; 4415833; -.
DR   GenomeReviews; CP000411_GR; OEOE_0158.
DR   KEGG; ooe:OEOE_0158; -.
DR   NMPDR; fig|203123.1.peg.790; -.
DR   OMA; Q04HC1; MYLMIRE.
DR   GO; GO:0000034; F:adenine deaminase activity; IEA:HAMAP.
DR   GO; GO:0030145; F:manganese ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006146; P:adenine catabolic process; IEA:InterPro.
DR   HAMAP; MF_01518; -; 1.
DR   InterPro; IPR006679; Adenine_deam.
DR   InterPro; IPR006680; Amidohydro_1.
DR   Pfam; PF01979; Amidohydro_1; 1.
DR   TIGRFAMs; TIGR01178; ade; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Manganese.
FT   CHAIN         1    553       Adenine deaminase 1.
FT                                /FTId=PRO_0000292389.
SQ   SEQUENCE   553 AA;  60871 MW;  C1F7C92271147EF0 CRC64;
     MGKQVYLHIF NAKILDVFNQ RFEDTELWID NGSIYFRGKS KDLTAKNNFN AEGNYIVPGL
     IDAHLHIESS LLAPSELAKL ELRHGVTSIF ADPHEIGSVS GVSGLFYMIQ EARNTPLHIH
     YMLPSSVPAT NFEHAGAVLH ADALKPFYGF PEINGLAEVM DFPAVANGDP DMLEKIRDAQ
     AAGHHADGHG AGLTREQLAV YRAVGIDTDH ESTSGKEALE RIQAGMKVFI REGTVERDEK
     SILPVVRKNN QSYFSFCTDD KSAIDIQKEG SVDNNVRLAI SKGIPAERAF TMASYNAAVA
     QHVKNVGALT DGFIADLVII SNLDNFVTEK VMTEGNWVDK LESKVTTFTS PAVNAELSLN
     DLKLPLKSDK AHVINIQPEH ITTKHTIESV NRDQQGNFVA DQDYAKIIVA ERYHNLGHGL
     GIIHGFNMQE GAIGSTIAHD SHNMIIAGVD DKPMIIAYDR LKRMGGGMIL VDKNGFTREL
     PLEIAGLMSD KPYQEVIAKQ KSLKGAFAKI SKGIDFDPFL TLSFMALPVI PSLKITDQGL
     FDFDQFKFID INA
//