Reviewed, UniProtKB/Swiss-Prot Q04G28 (SDHD_OENOB)

Names and origin

Protein names

Recommended name:
    Probable D-serine dehydratase
    EC=4.3.1.18
Alternative name(s):
    D-serine deaminase
      Short name=DSD

Gene names

Name:	dsdA
Ordered Locus Names:	OEOE_0657

Organism

Oenococcus oeni (strain BAA-331 / PSU-1) [Complete proteome] [HAMAP]

Taxonomic identifier

203123 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Oenococcus

Protein attributes

Sequence length	433 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	D-serine = pyruvate + NH3. HAMAP MF_01030
Cofactor	Pyridoxal phosphate By similarity.
Sequence similarities	Belongs to the serine/threonine dehydratase family. DsdA subfamily.

Ontologies

Keywords
Ligand	Pyridoxal phosphate
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	D-amino acid metabolic process Inferred from electronic annotation. Source: HAMAP
Molecular function	D-serine ammonia-lyase activity Inferred from electronic annotation. Source: EC hydro-lyase activity Inferred from electronic annotation. Source: HAMAP pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 433	433	Probable D-serine dehydratase HAMAP MF_01030		PRO_0000291734
Amino acid modifications
	Modified residue	110	1	N6-(pyridoxal phosphate)lysine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q04G28-1 [UniParc]. Last modified June 26, 2007. Version 2. Checksum: C36355D401651420	FASTA	433	48,272
	10 20 30 40 50 60 MTETLLKKKL NLNDQFLLNL KNYQEIFWKN PNYGDELPDL DVNRETIFQA NRRLERFAPY 70 80 90 100 110 120 LESVFSDTKR SKGIIESPIQ RMDSIKDLLS VKGSLLIKRD DLMPVSGSIK SRGGIYEVLC 130 140 150 160 170 180 FAEKIAIENG FDLKKDNYQD LRKDKYRKLF NQWRIEVAST GNLGLSVGLM ASTLGFKARI 190 200 210 220 230 240 HMSHDATDWK INKLLQNGVE VKIYDDNFSN AVAAARVSSQ RDPYSYFIDD EGSKLLFAGY 250 260 270 280 290 300 ATAGERVKKQ LSKMQIEVSK EHPLVVYLPA GVGGSPSGVA FGLKLQFADA VIPIFVEPTH 310 320 330 340 350 360 MPSVLLGMAS GLNHDISVYD IGIDGKTAAD GLAVGRPSMI AGKYMKDKLF GIATVSDSDM 370 380 390 400 410 420 FAYQGMLKKL ENIEVEPSAA VGIRGLIQSK EISEIPDSAT HMVWATGGSM VPKNTMHKYE 430 DKAVRIFNTW KSE

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000411 Genomic DNA. Translation: ABJ56594.1. Different initiation.
RefSeq	YP_810259.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	4416798.
GenomeReviews	Gene locus OEOE_0657 in contig CP000411_GR.
KEGG	ooe:OEOE_0657.
NMPDR	fig|203123.1.peg.535.
Organism-specific databases
CMR	Search...
Family and domain databases
HAMAP	MF_01030. [Tree]
InterPro	IPR011780. D_Ser_am_lyase. IPR001926. PyrdxlP-dep_enz_bsu. IPR000634. Ser/Thr_deHydtase_PyrdxlP-BS. [Graphical view]
PANTHER	PTHR10314:SF9. D_Ser_am_lyase. 1 hit.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
TIGRFAMs	TIGR02035. D_Ser_am_lyase. 1 hit.
PROSITE	PS00165. DEHYDRATASE_SER_THR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SDHD_OENOB

Accession

Primary (citable) accession number: Q04G28

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	June 26, 2007
Last modified:	June 16, 2009
This is version 17 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)