Q04DZ9 (ADEC2_OENOB) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase 2
Short name=Adenase 2
Short name=Adenine aminase 2
EC=3.5.4.2

Gene names

Name:	ade2
Ordered Locus Names:	OEOE_1462

Organism

Oenococcus oeni (strain ATCC BAA-331 / PSU-1) [Complete proteome] [HAMAP]

Taxonomic identifier

203123 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Oenococcus

Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 567	567	Adenine deaminase 2 HAMAP MF_01518		PRO_0000292390

Sequences

	Sequence		Length	Mass (Da)
	Q04DZ9 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: A544B8689616BC2E	FASTA	567	62,656
	10 20 30 40 50 60 MIKADLKIIN GQIYNTFTRQ FTAKEVAIVD GKFFQIADKL SDDFKFEDIL DLKGSYVIPG 70 80 90 100 110 120 LIDSHMHIES SMATPTNFSE TAIRFGTTTV IADAHEIANT SGIKGLKRFM DQPSLIDTFF 130 140 150 160 170 180 AIPSSVPSTN PELETTGGII DLEEVKELLA DPRIICLGEA MNFKGITSEP NSLIRKIIAL 190 200 210 220 230 240 CQKKRPRMPL EGHVPNISKE DLAKFIFAGI LSDHTQQTPA LIKEKIENGM FIQLQKKSLN 250 260 270 280 290 300 KENIETIVKN HFYDYSALVT DDTMADDLIN GHLNSIIKLA VKCGLPLEWA IYMTTYTPAQ 310 320 330 340 350 360 HMHFQDRGVI APGKIADFVV LNNLDGFSIK NVYKRGVPID KLSIDDEKPF ASEEYHSIYV 370 380 390 400 410 420 PNRSAKDFTL RVSKDLKKIT ANVIEIAAKG TFTKAVKKEL LVKDGIVDWQ KAGLALLAVQ 430 440 450 460 470 480 ERYGKTGQLT LALVSKSINK SGAIATTWAH DHHNLMVLGT NPDSMAIAYD KVASQQGGYL 490 500 510 520 530 540 VVKDKEIVAN VQLPIAGIIS DEPIDIIGHK LKKVRLAMKD LGYVNTNEIM SLSTLSLLVS 550 560 PSIKVSDKGI FDVKTQTKIP LLLAGEE

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-331 / PSU-1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000411 Genomic DNA. Translation: ABJ57323.1.
RefSeq	YP_810988.1. NC_008528.1.
3D structure databases
ProteinModelPortal	Q04DZ9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q04DZ9.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4415931.
GenomeReviews	Gene locus OEOE_1462 in contig CP000411_GR.
KEGG	ooe:OEOE_1462.
NMPDR	fig|203123.1.peg.1782.
PATRIC	22801152. VBIOenOen113004_1482.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1001.
HOGENOM	HBG725357.
OMA	IATTWAH.
PhylomeDB	Q04DZ9.
ProtClustDB	CLSK567048.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01486.
Pfam	PF01979. Amidohydro_1. 1 hit. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC2_OENOB

Accession

Primary (citable) accession number: Q04DZ9

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	November 14, 2006
Last modified:	January 25, 2012
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program