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Q04D15 (UPPP2_OENOB) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Ordered Locus Names:OEOE_1821
OrganismOenococcus oeni (strain ATCC BAA-331 / PSU-1) [Complete proteome] [HAMAP]
Taxonomic identifier203123 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesOenococcus

Protein attributes

Sequence length271 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 271271Undecaprenyl-diphosphatase 2 HAMAP-Rule MF_01006
PRO_0000290740

Regions

Transmembrane1 – 2121Helical; Potential
Transmembrane46 – 6621Helical; Potential
Transmembrane88 – 10821Helical; Potential
Transmembrane111 – 13121Helical; Potential
Transmembrane146 – 16621Helical; Potential
Transmembrane190 – 21021Helical; Potential
Transmembrane220 – 24021Helical; Potential
Transmembrane251 – 27121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q04D15 [UniParc].

Last modified November 14, 2006. Version 1.
Checksum: 0D102F988A22A78B

FASTA27129,785
        10         20         30         40         50         60 
MNFFQAIILA IAQGVSELFP ISSVAHSVII PYLFGWKLSP FFLKTNFLEF VVMMHIGTTI 

        70         80         90        100        110        120 
SLIVYFRKDW KKMLKSLFNK KTSKRNLALI VIGTIPAIIL GAIFEQTITN AFSDVIVASI 

       130        140        150        160        170        180 
FLIFNGLLLF FGEQTKKRGN KSIEDLKGWQ ALVIGCFQSL ALIPGFSRSG SSITAGFWMG 

       190        200        210        220        230        240 
LSNEESARFS MLLSTPMVAG AATLEIPKLI KNHVPGLLSL SLIGGIVAGL AAFLSIYILM 

       250        260        270 
HWFNHKKNNT MLPFAIYCIV IGIGVLASKA I 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000411 Genomic DNA. Translation: ABJ57657.1.
RefSeqYP_811322.1. NC_008528.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING203123.OEOE_1821.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABJ57657; ABJ57657; OEOE_1821.
GeneID4415374.
KEGGooe:OEOE_1821.
PATRIC22801918. VBIOenOen113004_1862.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218357.
KOK06153.
OMAFLEFVVM.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycOOEN203123:GHNL-1821-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameUPPP2_OENOB
AccessionPrimary (citable) accession number: Q04D15
Entry history
Integrated into UniProtKB/Swiss-Prot: June 12, 2007
Last sequence update: November 14, 2006
Last modified: February 19, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families