Q04D15 (UPPP2_OENOB) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 41.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Undecaprenyl-diphosphatase 2 EC=3.6.1.27 Alternative name(s): Bacitracin resistance protein 2 Undecaprenyl pyrophosphate phosphatase 2 | ||||
| Gene names |
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| Organism | Oenococcus oeni (strain ATCC BAA-331 / PSU-1) [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 203123 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Lactobacillales › Oenococcus |
Protein attributes
| Sequence length | 271 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP MF_01006 |
| Catalytic activity | Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006 |
| Subcellular location | Cell membrane; Multi-pass membrane protein By similarity HAMAP MF_01006. |
| Miscellaneous | Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006 |
| Sequence similarities | Belongs to the UppP family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Antibiotic resistance Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis |
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane Transmembrane helix |
| Molecular function | Hydrolase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW dephosphorylationInferred from electronic annotation. Source: InterPro peptidoglycan biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW regulation of cell shapeInferred from electronic annotation. Source: UniProtKB-KW response to antibioticInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | undecaprenyl-diphosphatase activity Inferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 271 | 271 | Undecaprenyl-diphosphatase 2 HAMAP MF_01006 | PRO_0000290740 | |||||
Regions | |||||||||
| Transmembrane | 1 – 21 | 21 | Helical; Potential | ||||||
| Transmembrane | 46 – 66 | 21 | Helical; Potential | ||||||
| Transmembrane | 88 – 108 | 21 | Helical; Potential | ||||||
| Transmembrane | 111 – 131 | 21 | Helical; Potential | ||||||
| Transmembrane | 146 – 166 | 21 | Helical; Potential | ||||||
| Transmembrane | 190 – 210 | 21 | Helical; Potential | ||||||
| Transmembrane | 220 – 240 | 21 | Helical; Potential | ||||||
| Transmembrane | 251 – 271 | 21 | Helical; Potential | ||||||
Sequences
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References
| [1] | "Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. Mills D.A.Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-331 / PSU-1. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000411 Genomic DNA. Translation: ABJ57657.1. |
| RefSeq | YP_811322.1. NC_008528.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q04D15. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| GeneID | 4415374. |
| GenomeReviews | Gene locus OEOE_1821 in contig CP000411_GR. |
| KEGG | ooe:OEOE_1821. |
| NMPDR | fig|203123.1.peg.193. |
| PATRIC | 22801918. VBIOenOen113004_1862. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG1968. |
| HOGENOM | HBG391969. |
| OMA | CLAFLPG. |
| PhylomeDB | Q04D15. |
Family and domain databases | |
| HAMAP | MF_01006. Undec_diphosphatase. [Tree] |
| InterPro | IPR003824. Bacitracin-R_BacA. [Graphical view] |
| KO | K06153. |
| Pfam | PF02673. BacA. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | UPPP2_OENOB | ||||||||
| Accession | Primary (citable) accession number: Q04D15 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |

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