Q04CE3 (Q04CE3_LACDB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase HAMAP-Rule MF_01039
Short name=BPG-dependent PGAM HAMAP-Rule MF_01039
Short name=PGAM HAMAP-Rule MF_01039
Short name=Phosphoglyceromutase HAMAP-Rule MF_01039
Short name=dPGM HAMAP-Rule MF_01039
EC=5.4.2.1 HAMAP-Rule MF_01039

Gene names

Name:	gpmA HAMAP-Rule MF_01039
Ordered Locus Names:	LBUL_0203

Organism

Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365) [Complete proteome] [HAMAP] EMBL ABJ57879.1

Taxonomic identifier

321956 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus delbrueckii › Lactobacillus delbrueckii subsp. bulgaricus

Protein attributes

Sequence length	229 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP-Rule MF_01039 RuleBase RU004512
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP-Rule MF_01039 RuleBase RU004512 SAAS SAAS013078
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP-Rule MF_01039 RuleBase RU004512
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily. HAMAP-Rule MF_01039

Ontologies

Keywords
Biological process	Glycolysis HAMAP-Rule MF_01039 SAAS SAAS013078
Molecular function	Isomerase SAAS SAAS013078 HAMAP-Rule MF_01039 EMBL ABJ57879.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: HAMAP
Molecular_function	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity HAMAP-Rule MF_01039
	Active site	182	1	By similarity HAMAP-Rule MF_01039
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity HAMAP-Rule MF_01039

Sequences

	Sequence		Length	Mass (Da)
	Q04CE3 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: 343F504EB9F04111	FASTA	229	26,091
	10 20 30 40 50 60 MSKLVLIRHG QSEWNLSNQF TGWVDVNLSD KGVEEAKKAG RLIKEAGLEF DQAYTSVLTR 70 80 90 100 110 120 AIKTLHFALE ESGQLWVPET KSWRLNERHY GALQGLNKAE TAEKYGDEQV HIWRRSYDVL 130 140 150 160 170 180 PPVLADDSEF SQANDRRYAN LDPHIVPKAE NLKVTLDRVM PFWEDHIAPD LLAGKNVIIA 190 200 210 220 AHGNSLRALT KYIENISDED IMDVEMKTGE PVVYTFDDKL NVVSKEKLD

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B., Mills D. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC BAA-365.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000412 Genomic DNA. Translation: ABJ57879.1.
RefSeq	YP_812317.1. NC_008529.1.
3D structure databases
ProteinModelPortal	Q04CE3.
SMR	Q04CE3. Positions 1-228.
ModBase	Search...
Protein-protein interaction databases
STRING	321956.LBUL_0203.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	ABJ57879; ABJ57879; LBUL_0203.
GeneID	4436232.
KEGG	lbu:LBUL_0203.
PATRIC	22220225. VBILacDel70259_0203.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0588.
HOGENOM	HOG000221682.
KO	K01834.
OMA	GQSDWNL.
ProtClustDB	PRK14116.
Enzyme and pathway databases
BioCyc	LDEL321956:GI15-323-MONOMER.
UniPathway	UPA00109; UER00186.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA.
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
PANTHER	PTHR11931. PTHR11931. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q04CE3_LACDB

Accession

Primary (citable) accession number: Q04CE3

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)