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Q04B18

- SYR_LACDB

UniProt

Q04B18 - SYR_LACDB

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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

  1. arginine-tRNA ligase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciLDEL321956:GI15-737-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:LBUL_0739
OrganismiLactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365)
Taxonomic identifieri321956 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000665: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 565565Arginine--tRNA ligasePRO_1000018049Add
BLAST

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi321956.LBUL_0739.

Structurei

3D structure databases

ProteinModelPortaliQ04B18.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi121 – 13111"HIGH" regionAdd
BLAST

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0018.
HOGENOMiHOG000247211.
KOiK01887.
OMAiYVKFHDE.
OrthoDBiEOG6JB13C.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPiMF_00123. Arg_tRNA_synth.
InterProiIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSiPR01038. TRNASYNTHARG.
SMARTiSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04B18-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNGKQLVAEA LQAVLPDWSL DDIDVKIERP KDEKLGDYAF PTFTLAKTMR
60 70 80 90 100
KAPNLIAVEL AEKIDQGSFE KVEAVGPYIN FFLDKSQTGA AILQEILADP
110 120 130 140 150
ENYGARDLGH GRNVLTEYSS PNIAKPMGMG HLRSTMIGEA IARILAKEGF
160 170 180 190 200
KPIRIDYLGD WGTQFGKMMA AYKMWGNDAD IEKDPINTLL SYYVRINREA
210 220 230 240 250
EEHPEYDEDG REWFSKLEHG DEEAKRLWSW FREVSLERFK KVYDMLDVHF
260 270 280 290 300
DSFTGEAFSA QMMDKPIQIL REKGLLVKSQ GAEIVDLEKY NLPPLMVIKS
310 320 330 340 350
NGTSTYITRD LATAMYRKKT YGFYKSIYVV GQEQEVYFQQ LRACLKEMGF
360 370 380 390 400
DWADDIVHIS FGLMSINGQK MSTRKGNVVN LEDVLNESVD LARKQISEKN
410 420 430 440 450
AGLKNADEVA KQVGIGAVVF HDLKNYRRNP IDFNLEEVVK FEGETGPYVQ
460 470 480 490 500
YARARGESLL RKSGITDFSD ADLTKIGAEE WDLVSFMARY ADTIQKAMET
510 520 530 540 550
YDPSAIAKYA LELAKRFNKY YAHTRILVDD VDEDVKKARL AVVQAVSHVI
560
KSALDLLDVK APDEM
Length:565
Mass (Da):64,168
Last modified:November 14, 2006 - v1
Checksum:i10FC61F9DBFA6E8A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000412 Genomic DNA. Translation: ABJ58354.1.
RefSeqiYP_812792.1. NC_008529.1.

Genome annotation databases

EnsemblBacteriaiABJ58354; ABJ58354; LBUL_0739.
GeneIDi4435897.
KEGGilbu:LBUL_0739.
PATRICi22221327. VBILacDel70259_0736.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000412 Genomic DNA. Translation: ABJ58354.1 .
RefSeqi YP_812792.1. NC_008529.1.

3D structure databases

ProteinModelPortali Q04B18.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 321956.LBUL_0739.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ58354 ; ABJ58354 ; LBUL_0739 .
GeneIDi 4435897.
KEGGi lbu:LBUL_0739.
PATRICi 22221327. VBILacDel70259_0736.

Phylogenomic databases

eggNOGi COG0018.
HOGENOMi HOG000247211.
KOi K01887.
OMAi YVKFHDE.
OrthoDBi EOG6JB13C.

Enzyme and pathway databases

BioCyci LDEL321956:GI15-737-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPi MF_00123. Arg_tRNA_synth.
InterProi IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view ]
PANTHERi PTHR11956. PTHR11956. 1 hit.
Pfami PF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view ]
PRINTSi PR01038. TRNASYNTHARG.
SMARTi SM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view ]
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsi TIGR00456. argS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC BAA-365.

Entry informationi

Entry nameiSYR_LACDB
AccessioniPrimary (citable) accession number: Q04B18
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: October 29, 2014
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3