Q049K1 (Q049K1_LACDB) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Cysteine synthase RuleBase RU003985
EC=2.5.1.47 RuleBase RU003985

Gene names

Ordered Locus Names:

LBUL_1354

Organism

Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC BAA-365) [Complete proteome] [HAMAP]

Taxonomic identifier

321956 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	307 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	O(3)-acetyl-L-serine + H2S = L-cysteine + acetate. RuleBase RU003985
Sequence similarities	Belongs to the cysteine synthase/cystathionine beta-synthase family. RuleBase RU003985

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Cysteine biosynthesis RuleBase RU003985
Molecular function	Transferase RuleBase RU003985 EMBL ABJ58871.1
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cysteine biosynthetic process from serine Inferred from electronic annotation. Source: InterPro
Molecular function	cysteine synthase activity Inferred from electronic annotation. Source: EC pyridoxal phosphate binding Inferred from electronic annotation. Source: InterPro transferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q049K1 [UniParc]. Last modified November 14, 2006. Version 1. Checksum: FD2DDFE72B9515AD	FASTA	307	32,445
	10 20 30 40 50 60 MSTDRIYGNI LETIGHTPIV KLNRVVPEGA ADVYVKLEFF NPGGSIKDRI ALAMIEKAEK 70 80 90 100 110 120 EGKLKPGDTI VEPTSGNTGI GLAAVASAKG YHLIIAMPET MSEERKKIMR AYGAELLLTP 130 140 150 160 170 180 GKDGMPGSIA LAEKLVKEKG YFMPMQFENP ANPEIHELTT GQEIVNAFAG DLPDAFVAGV 190 200 210 220 230 240 GTGSTLTGIG RALKKAGDVK VYALEPAESP LLKEGKKGPH KIQGISAGFI PKTLDQSIYD 250 260 270 280 290 300 GIVEVSSDDA FATAREVARL EGFLPGISAG ANIHGAIELA KKLGAGKKVV TVAPDNGERY LSTALYQ

References

[1]

"Comparative genomics of the lactic acid bacteria." Makarova K.S., Slesarev A., Wolf Y.I., Sorokin A., Mirkin B., Koonin E.V., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. , Plengvidhya V., Welker D., Hughes J., Goh Y., Benson A., Baldwin K., Lee J.-H., Diaz-Muniz I., Dosti B., Smeianov V., Wechter W., Barabote R., Lorca G., Altermann E., Barrangou R., Ganesan B., Xie Y., Rawsthorne H., Tamir D., Parker C., Breidt F., Broadbent J.R., Hutkins R., O'Sullivan D., Steele J., Unlu G., Saier M.H. Jr., Klaenhammer T., Richardson P., Kozyavkin S., Weimer B.C., Mills D.A. Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed: 17030793] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000412 Genomic DNA. Translation: ABJ58871.1.
RefSeq	YP_813309.1. NC_008529.1.
3D structure databases
ProteinModelPortal	Q049K1.
SMR	Q049K1. Positions 4-307.
ModBase	Search...
Protein-protein interaction databases
STRING	Q049K1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	4435235.
GenomeReviews	Gene locus LBUL_1354 in contig CP000412_GR.
KEGG	lbu:LBUL_1354.
PATRIC	22222563. VBILacDel70259_1330.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0031.
HOGENOM	HBG748215.
OMA	SAGANIH.
ProtClustDB	CLSK936836.
Family and domain databases
InterPro	IPR001216. Cys_synth_BS. IPR005856. Cys_synthKM. IPR005859. CysK. IPR001926. PyrdxlP-dep_enz_bsu. [Graphical view]
KO	K01738.
Pfam	PF00291. PALP. 1 hit. [Graphical view]
SUPFAM	SSF53686. PyrdxlP-dep_enz_bsu. 1 hit.
TIGRFAMs	TIGR01139. CysK. 1 hit. TIGR01136. CysKM. 1 hit.
PROSITE	PS00901. CYS_SYNTHASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q049K1_LACDB

Accession

Primary (citable) accession number: Q049K1

Entry history

Integrated into UniProtKB/TrEMBL:	November 14, 2006
Last sequence update:	November 14, 2006
Last modified:	December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)