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Protein

Probable family 17 glucosidase SCW10

Gene

SCW10

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation.By similarity

Miscellaneous

Present with 10500 molecules/cell in log phase SD medium.1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei326NucleophileBy similarity1
Active sitei380Proton donorBy similarity1

GO - Molecular functioni

  • glucosidase activity Source: SGD

GO - Biological processi

  • carbohydrate metabolic process Source: InterPro
  • cell wall organization Source: UniProtKB-KW
  • conjugation with cellular fusion Source: SGD

Keywordsi

Molecular functionGlycosidase, Hydrolase
Biological processCell wall biogenesis/degradation

Enzyme and pathway databases

BioCyciYEAST:YMR305C-MONOMER

Protein family/group databases

CAZyiGH17 Glycoside Hydrolase Family 17

Names & Taxonomyi

Protein namesi
Recommended name:
Probable family 17 glucosidase SCW10 (EC:3.2.1.-)
Alternative name(s):
Soluble cell wall protein 10
Gene namesi
Name:SCW10
Ordered Locus Names:YMR305C
ORF Names:YM9952.07C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR305C
SGDiS000004921 SCW10

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell wall, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 18Sequence analysisAdd BLAST18
PropeptideiPRO_000001190119 – 291 PublicationAdd BLAST11
ChainiPRO_000001190230 – 389Probable family 17 glucosidase SCW10Add BLAST360

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi279N-linked (GlcNAc...) asparagineSequence analysis1

Post-translational modificationi

Glycosylated.

Keywords - PTMi

Cleavage on pair of basic residues, Glycoprotein

Proteomic databases

MaxQBiQ04951
PaxDbiQ04951
PRIDEiQ04951

Miscellaneous databases

PMAP-CutDBQ04951

Interactioni

Protein-protein interaction databases

BioGridi35485, 40 interactors
DIPiDIP-3845N
IntActiQ04951, 1 interactor
STRINGi4932.YMR305C

Structurei

3D structure databases

ProteinModelPortaliQ04951
SMRiQ04951
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi65 – 134Ser-richAdd BLAST70

Sequence similaritiesi

Belongs to the glycosyl hydrolase 17 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

GeneTreeiENSGT00390000008245
HOGENOMiHOG000216601
InParanoidiQ04951
OMAiGQKLFLG
OrthoDBiEOG092C20DF

Family and domain databases

InterProiView protein in InterPro
IPR000490 Glyco_hydro_17
IPR017853 Glycoside_hydrolase_SF
PfamiView protein in Pfam
PF00332 Glyco_hydro_17, 1 hit
SUPFAMiSSF51445 SSF51445, 1 hit
PROSITEiView protein in PROSITE
PS00587 GLYCOSYL_HYDROL_F17, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q04951-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFSNFLTVS ALLTGALGAP AVRHKHEKRD VVTATVHAQV TVVVSGNSGE
60 70 80 90 100
TIVPVNENAV VATTSSTAVA SQATTSTLEP TTSANVVTSQ QQTSTLQSSE
110 120 130 140 150
AASTVGSSTS SSPSSSSSTS SSASSSASSS ISASGAKGIT YSPYNDDGSC
160 170 180 190 200
KSTAQVASDL EQLTGFDNIR LYGVDCSQVE NVLQAKTSSQ KLFLGIYYVD
210 220 230 240 250
KIQDAVDTIK SAVESYGSWD DITTVSVGNE LVNGGSATTT QVGEYVSTAK
260 270 280 290 300
SALTSAGYTG SVVSVDTFIA VINNPDLCNY SDYMAVNAHA YFDENTAAQD
310 320 330 340 350
AGPWVLEQIE RVYTACGGKK DVVITETGWP SKGDTYGEAV PSKANQEAAI
360 370 380
SSIKSSCGSS AYLFTAFNDL WKDDGQYGVE KYWGILSSD
Length:389
Mass (Da):40,469
Last modified:November 1, 1997 - v1
Checksum:i21F394BD41337DE1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti38 – 39AQ → QE AA sequence (PubMed:9748433).Curated2

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z49212 Genomic DNA Translation: CAA89138.1
BK006946 Genomic DNA Translation: DAA10206.1
PIRiS53975
RefSeqiNP_014035.1, NM_001182815.1

Genome annotation databases

EnsemblFungiiYMR305C; YMR305C; YMR305C
GeneIDi855352
KEGGisce:YMR305C

Similar proteinsi

Entry informationi

Entry nameiSCW10_YEAST
AccessioniPrimary (citable) accession number: Q04951
Secondary accession number(s): D6W0D2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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