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Protein

Reticulon-like protein 1

Gene

RTN1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 37105 molecules/cell in log phase SD medium.1 Publication

GO - Biological processi

  • endoplasmic reticulum inheritance Source: SGD
  • endoplasmic reticulum organization Source: UniProtKB
  • endoplasmic reticulum tubular network maintenance Source: SGD
  • endoplasmic reticulum tubular network organization Source: UniProtKB
  • ER-dependent peroxisome organization Source: SGD
  • nuclear pore complex assembly Source: SGD
  • response to endoplasmic reticulum stress Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-29810-MONOMER

Protein family/group databases

TCDBi8.A.102.1.4 the reticulon (reticulon) family

Names & Taxonomyi

Protein namesi
Recommended name:
Reticulon-like protein 1
Gene namesi
Name:RTN1
Ordered Locus Names:YDR233C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR233C
SGDiS000002641 RTN1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 50CytoplasmicSequence analysisAdd BLAST50
Transmembranei51 – 73HelicalSequence analysisAdd BLAST23
Topological domaini74 – 142LumenalSequence analysisAdd BLAST69
Transmembranei143 – 163HelicalSequence analysisAdd BLAST21
Topological domaini164 – 295CytoplasmicSequence analysisAdd BLAST132

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001681681 – 295Reticulon-like protein 1Add BLAST295

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei186PhosphothreonineCombined sources1
Modified residuei219PhosphothreonineCombined sources1
Modified residuei232PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ04947
PaxDbiQ04947
PRIDEiQ04947
TopDownProteomicsiQ04947

PTM databases

CarbonylDBiQ04947
iPTMnetiQ04947

Interactioni

Subunit structurei

Interacts with POM33.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi32284, 166 interactors
DIPiDIP-4090N
IntActiQ04947, 25 interactors
MINTiQ04947
STRINGi4932.YDR233C

Structurei

3D structure databases

ProteinModelPortaliQ04947
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini20 – 220ReticulonPROSITE-ProRule annotationAdd BLAST201

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili265 – 295Sequence analysisAdd BLAST31

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi9 – 16Poly-Gln8

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

GeneTreeiENSGT00530000066264
HOGENOMiHOG000248018
InParanoidiQ04947
OMAiFFVIEAQ
OrthoDBiEOG092C4TX2

Family and domain databases

InterProiView protein in InterPro
IPR003388 Reticulon
PfamiView protein in Pfam
PF02453 Reticulon, 1 hit
PROSITEiView protein in PROSITE
PS50845 RETICULON, 1 hit

Sequencei

Sequence statusi: Complete.

Q04947-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSASAQHSQA QQQQQQKSCN CDLLLWRNPV QTGKYFGGSL LALLILKKVN
60 70 80 90 100
LITFFLKVAY TILFTTGSIE FVSKLFLGQG LITKYGPKEC PNIAGFIKPH
110 120 130 140 150
IDEALKQLPV FQAHIRKTVF AQVPKHTFKT AVALFLLHKF FSWFSIWTIV
160 170 180 190 200
FVADIFTFTL PVIYHSYKHE IDATVAQGVE ISKQKTQEFS QMACEKTKPY
210 220 230 240 250
LDKVESKLGP ISNLVKSKTA PVSSTAGPQT ASTSKLAADV PLEPESKAYT
260 270 280 290
SSAQVMPEVP QHEPSTTQEF NVDELSNELK KSTKNLQNEL EKNNA
Length:295
Mass (Da):32,916
Last modified:November 1, 1996 - v1
Checksum:i245575E65D3C2193
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY164798 mRNA Translation: AAP47373.1
Z48612 Genomic DNA Translation: CAA88512.1
AY558579 Genomic DNA Translation: AAS56905.1
BK006938 Genomic DNA Translation: DAA12074.1
PIRiS59439
RefSeqiNP_010519.3, NM_001180541.3

Genome annotation databases

EnsemblFungiiYDR233C; YDR233C; YDR233C
GeneIDi851819
KEGGisce:YDR233C

Similar proteinsi

Entry informationi

Entry nameiRTN1_YEAST
AccessioniPrimary (citable) accession number: Q04947
Secondary accession number(s): D6VSL4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 22, 2005
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 139 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

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