Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q04900

- MUC24_HUMAN

UniProt

Q04900 - MUC24_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Sialomucin core protein 24

Gene

CD164

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli

Functioni

Sialomucin that may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Modulates the migration of umbilical cord blood CD133+ cells and this is mediated through the CXCL12/CXCR4 axis. May play an important role in prostate cancer metastasis and the infiltration of bone marrow by cancer cells. Promotes myogenesis by enhancing CXCR4-dependent cell motility. Positively regulates myoblast migration and promotes myoblast fusion into myotubes By similarity.By similarity

GO - Biological processi

  1. cell adhesion Source: MGI
  2. hemopoiesis Source: UniProtKB
  3. heterophilic cell-cell adhesion Source: MGI
  4. immune response Source: ProtInc
  5. multicellular organismal development Source: ProtInc
  6. muscle organ development Source: UniProtKB-KW
  7. negative regulation of cell adhesion Source: UniProtKB
  8. negative regulation of cell proliferation Source: UniProtKB
  9. signal transduction Source: ProtInc
Complete GO annotation...

Keywords - Biological processi

Cell adhesion, Myogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Sialomucin core protein 24
Short name:
MUC-24
Alternative name(s):
Endolyn
Multi-glycosylated core protein 24
Short name:
MGC-24
Short name:
MGC-24v
CD_antigen: CD164
Gene namesi
Name:CD164
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 6

Organism-specific databases

HGNCiHGNC:1632. CD164.

Subcellular locationi

Lysosome membrane 1 Publication; Single-pass type I membrane protein 1 Publication. Endosome membrane 1 Publication; Single-pass type I membrane protein 1 Publication. Cell membrane 1 Publication; Single-pass type I membrane protein 1 Publication

GO - Cellular componenti

  1. endosome Source: UniProtKB
  2. extracellular region Source: UniProtKB-KW
  3. integral component of plasma membrane Source: UniProtKB
  4. lysosome Source: UniProtKB
  5. plasma membrane Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Endosome, Lysosome, Membrane, Secreted

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26191.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence AnalysisAdd
BLAST
Chaini24 – 197174Sialomucin core protein 24PRO_0000019292Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi26 – 261N-linked (GlcNAc...)Sequence Analysis
Glycosylationi32 – 321N-linked (GlcNAc...)Sequence Analysis
Glycosylationi41 – 411N-linked (GlcNAc...)Sequence Analysis
Glycosylationi72 – 721N-linked (GlcNAc...)Sequence Analysis
Glycosylationi77 – 771N-linked (GlcNAc...)Sequence Analysis
Glycosylationi94 – 941N-linked (GlcNAc...)Sequence Analysis
Glycosylationi104 – 1041N-linked (GlcNAc...)Sequence Analysis
Glycosylationi121 – 1211N-linked (GlcNAc...)Sequence Analysis
Glycosylationi142 – 1421O-linked (Xyl...) (glycosaminoglycan)Sequence Analysis
Glycosylationi146 – 1461N-linked (GlcNAc...)Sequence Analysis

Post-translational modificationi

Highly N- and O-glycosylated; contains sialic acid.1 Publication
The motif Ser-Gly may serve as the site of attachment of a glycosaminoglycan side chain.

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ04900.
PaxDbiQ04900.
PRIDEiQ04900.

Expressioni

Tissue specificityi

Isoform 1 and isoform 3 are expressed in hematopoietic and non-hematopoietic tissues. Isoform 1 is expressed by prostate cancer tumors and prostate cancer cell lines. The expression is greater in bone metastases than in primary tumors. Expression in osseous metastasis is greater than that in soft tissue metastasis. Isoform 2 is expressed in the small intestine, colon, lung, thyroid and in colorectal and pancreatic adenocarcinoma. Isoform 4 is expressed by both hematopoietic progenitor cells and bone marrow stromal cells.5 Publications

Inductioni

Up-regulated by CXCL12 in prostate cancer cell lines.1 Publication

Gene expression databases

BgeeiQ04900.
CleanExiHS_CD164.
ExpressionAtlasiQ04900. baseline and differential.
GenevestigatoriQ04900.

Organism-specific databases

HPAiHPA010636.

Interactioni

Subunit structurei

Homodimer (isoform 4). Interacts with CXCR4.2 Publications

Binary interactionsi

WithEntry#Exp.IntActNotes
CXCR4P610732EBI-2115896,EBI-489411

Protein-protein interaction databases

BioGridi114297. 2 interactions.
IntActiQ04900. 9 interactions.
MINTiMINT-5225006.
STRINGi9606.ENSP00000309376.

Structurei

3D structure databases

ProteinModelPortaliQ04900.
ModBaseiSearch...
MobiDBiSearch...

Topological domain

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini24 – 162139ExtracellularSequence AnalysisAdd
BLAST
Topological domaini184 – 19714CytoplasmicSequence AnalysisAdd
BLAST

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei163 – 18321HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni191 – 1977Required for endosomal and lysosomal localizationBy similarity

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi105 – 15248Thr-richAdd
BLAST

Sequence similaritiesi

Belongs to the CD164 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG77756.
GeneTreeiENSGT00530000063929.
HOVERGENiHBG052534.
InParanoidiQ04900.
KOiK06546.
OrthoDBiEOG7XDBJ6.
PhylomeDBiQ04900.
TreeFamiTF333380.

Family and domain databases

InterProiIPR007947. CD164_MGC24.
[Graphical view]
PANTHERiPTHR11337. PTHR11337. 1 hit.
PfamiPF05283. MGC-24. 1 hit.
[Graphical view]
PRINTSiPR01701. CD164ANTIGEN.

Sequences (5)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 5 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q04900-1) [UniParc]FASTAAdd to Basket

Also known as: CD164(E1-6)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSRLSRSLLW AATCLGVLCV LSADKNTTQH PNVTTLAPIS NVTSAPVTSL
60 70 80 90 100
PLVTTPAPET CEGRNSCVSC FNVSVVNTTC FWIECKDESY CSHNSTVSDC
110 120 130 140 150
QVGNTTDFCS VSTATPVPTA NSTAKPTVQP SPSTTSKTVT TSGTTNNTVT
160 170 180 190
PTSQPVRKST FDAASFIGGI VLVLGVQAVI FFLYKFCKSK ERNYHTL
Length:197
Mass (Da):20,917
Last modified:September 1, 2009 - v2
Checksum:i4855E02646F4CB35
GO
Isoform 2 (identifier: Q04900-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     175-197: GVQAVIFFLYKFCKSKERNYHTL → EIRCHTRNYIPDLKK

Show »
Length:189
Mass (Da):20,011
Checksum:iAC1E49F139D50B10
GO
Isoform 3 (identifier: Q04900-3) [UniParc]FASTAAdd to Basket

Also known as: CD164(Delta 4)

The sequence of this isoform differs from the canonical sequence as follows:
     111-123: Missing.

Show »
Length:184
Mass (Da):19,689
Checksum:iFB689B760D2EE1FC
GO
Isoform 4 (identifier: Q04900-4) [UniParc]FASTAAdd to Basket

Also known as: CD164(Delta 5)

The sequence of this isoform differs from the canonical sequence as follows:
     124-142: Missing.

Show »
Length:178
Mass (Da):19,017
Checksum:i06FC14ECF6372314
GO
Isoform 5 (identifier: Q04900-5) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     143-157: GTTNNTVTPTSQPVR → EIRCHTRNYIPDLKK
     158-197: Missing.

Show »
Length:157
Mass (Da):16,736
Checksum:i9F0212BE11D4F958
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei111 – 12313Missing in isoform 3. 2 PublicationsVSP_037972Add
BLAST
Alternative sequencei124 – 14219Missing in isoform 4. 3 PublicationsVSP_037973Add
BLAST
Alternative sequencei143 – 15715GTTNN…SQPVR → EIRCHTRNYIPDLKK in isoform 5. 1 PublicationVSP_038018Add
BLAST
Alternative sequencei158 – 19740Missing in isoform 5. 1 PublicationVSP_038019Add
BLAST
Alternative sequencei175 – 19723GVQAV…NYHTL → EIRCHTRNYIPDLKK in isoform 2. 1 PublicationVSP_037974Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D14043 mRNA. Translation: BAA03130.1.
AF106518 mRNA. Translation: AAC82473.1.
AF263279 mRNA. Translation: AAF85965.1.
AF299341 mRNA. Translation: AAG53906.1.
AF299342 mRNA. Translation: AAG53907.1.
AF299343 mRNA. Translation: AAG53908.1.
AF299340 Genomic DNA. Translation: AAG53903.1.
AF299340 Genomic DNA. Translation: AAG53904.1.
AF299340 Genomic DNA. Translation: AAG53905.1.
AK298684 mRNA. Translation: BAG60847.1.
AK303525 mRNA. Translation: BAG64553.1.
AK312357 mRNA. Translation: BAG35275.1.
AK315908 mRNA. Translation: BAH14279.1.
AL359711 Genomic DNA. Translation: CAI40700.1.
AL359711 Genomic DNA. Translation: CAI40702.1.
AL359711 Genomic DNA. Translation: CAI40704.1.
CH471051 Genomic DNA. Translation: EAW48348.1.
CH471051 Genomic DNA. Translation: EAW48352.1.
CH471051 Genomic DNA. Translation: EAW48349.1.
CH471051 Genomic DNA. Translation: EAW48353.1.
CH471051 Genomic DNA. Translation: EAW48354.1.
CH471051 Genomic DNA. Translation: EAW48355.1.
BC011522 mRNA. Translation: AAH11522.1.
CCDSiCCDS47462.1. [Q04900-5]
CCDS47463.1. [Q04900-2]
CCDS47464.1. [Q04900-3]
CCDS47465.1. [Q04900-4]
CCDS5073.1. [Q04900-1]
PIRiJX0235.
RefSeqiNP_001135873.1. NM_001142401.1. [Q04900-3]
NP_001135874.1. NM_001142402.1. [Q04900-4]
NP_001135875.1. NM_001142403.1. [Q04900-2]
NP_001135876.1. NM_001142404.1. [Q04900-5]
NP_006007.2. NM_006016.4. [Q04900-1]
UniGeneiHs.520313.

Genome annotation databases

EnsembliENST00000275080; ENSP00000275080; ENSG00000135535. [Q04900-3]
ENST00000310786; ENSP00000309376; ENSG00000135535. [Q04900-1]
ENST00000324953; ENSP00000314177; ENSG00000135535. [Q04900-4]
ENST00000413644; ENSP00000402237; ENSG00000135535. [Q04900-2]
ENST00000512821; ENSP00000427546; ENSG00000135535. [Q04900-5]
GeneIDi8763.
KEGGihsa:8763.
UCSCiuc003ptd.3. human. [Q04900-2]
uc003pte.3. human. [Q04900-1]
uc003ptf.3. human. [Q04900-4]
uc010kdn.3. human. [Q04900-3]
uc011eap.2. human. [Q04900-5]

Polymorphism databases

DMDMi257051036.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D14043 mRNA. Translation: BAA03130.1 .
AF106518 mRNA. Translation: AAC82473.1 .
AF263279 mRNA. Translation: AAF85965.1 .
AF299341 mRNA. Translation: AAG53906.1 .
AF299342 mRNA. Translation: AAG53907.1 .
AF299343 mRNA. Translation: AAG53908.1 .
AF299340 Genomic DNA. Translation: AAG53903.1 .
AF299340 Genomic DNA. Translation: AAG53904.1 .
AF299340 Genomic DNA. Translation: AAG53905.1 .
AK298684 mRNA. Translation: BAG60847.1 .
AK303525 mRNA. Translation: BAG64553.1 .
AK312357 mRNA. Translation: BAG35275.1 .
AK315908 mRNA. Translation: BAH14279.1 .
AL359711 Genomic DNA. Translation: CAI40700.1 .
AL359711 Genomic DNA. Translation: CAI40702.1 .
AL359711 Genomic DNA. Translation: CAI40704.1 .
CH471051 Genomic DNA. Translation: EAW48348.1 .
CH471051 Genomic DNA. Translation: EAW48352.1 .
CH471051 Genomic DNA. Translation: EAW48349.1 .
CH471051 Genomic DNA. Translation: EAW48353.1 .
CH471051 Genomic DNA. Translation: EAW48354.1 .
CH471051 Genomic DNA. Translation: EAW48355.1 .
BC011522 mRNA. Translation: AAH11522.1 .
CCDSi CCDS47462.1. [Q04900-5 ]
CCDS47463.1. [Q04900-2 ]
CCDS47464.1. [Q04900-3 ]
CCDS47465.1. [Q04900-4 ]
CCDS5073.1. [Q04900-1 ]
PIRi JX0235.
RefSeqi NP_001135873.1. NM_001142401.1. [Q04900-3 ]
NP_001135874.1. NM_001142402.1. [Q04900-4 ]
NP_001135875.1. NM_001142403.1. [Q04900-2 ]
NP_001135876.1. NM_001142404.1. [Q04900-5 ]
NP_006007.2. NM_006016.4. [Q04900-1 ]
UniGenei Hs.520313.

3D structure databases

ProteinModelPortali Q04900.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 114297. 2 interactions.
IntActi Q04900. 9 interactions.
MINTi MINT-5225006.
STRINGi 9606.ENSP00000309376.

Polymorphism databases

DMDMi 257051036.

Proteomic databases

MaxQBi Q04900.
PaxDbi Q04900.
PRIDEi Q04900.

Protocols and materials databases

DNASUi 8763.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000275080 ; ENSP00000275080 ; ENSG00000135535 . [Q04900-3 ]
ENST00000310786 ; ENSP00000309376 ; ENSG00000135535 . [Q04900-1 ]
ENST00000324953 ; ENSP00000314177 ; ENSG00000135535 . [Q04900-4 ]
ENST00000413644 ; ENSP00000402237 ; ENSG00000135535 . [Q04900-2 ]
ENST00000512821 ; ENSP00000427546 ; ENSG00000135535 . [Q04900-5 ]
GeneIDi 8763.
KEGGi hsa:8763.
UCSCi uc003ptd.3. human. [Q04900-2 ]
uc003pte.3. human. [Q04900-1 ]
uc003ptf.3. human. [Q04900-4 ]
uc010kdn.3. human. [Q04900-3 ]
uc011eap.2. human. [Q04900-5 ]

Organism-specific databases

CTDi 8763.
GeneCardsi GC06M109687.
HGNCi HGNC:1632. CD164.
HPAi HPA010636.
MIMi 603356. gene.
neXtProti NX_Q04900.
PharmGKBi PA26191.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG77756.
GeneTreei ENSGT00530000063929.
HOVERGENi HBG052534.
InParanoidi Q04900.
KOi K06546.
OrthoDBi EOG7XDBJ6.
PhylomeDBi Q04900.
TreeFami TF333380.

Miscellaneous databases

ChiTaRSi CD164. human.
GeneWikii CD164.
GenomeRNAii 8763.
NextBioi 32868.
PROi Q04900.
SOURCEi Search...

Gene expression databases

Bgeei Q04900.
CleanExi HS_CD164.
ExpressionAtlasi Q04900. baseline and differential.
Genevestigatori Q04900.

Family and domain databases

InterProi IPR007947. CD164_MGC24.
[Graphical view ]
PANTHERi PTHR11337. PTHR11337. 1 hit.
Pfami PF05283. MGC-24. 1 hit.
[Graphical view ]
PRINTSi PR01701. CD164ANTIGEN.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A novel core protein as well as polymorphic epithelial mucin carry peanut agglutinin binding sites in human gastric carcinoma cells: sequence analysis and examination of gene expression."
    Masuzawa Y., Miyauchi T., Hamanoue M., Ando S., Yoshida J., Takao S., Shimazu H., Adachi M., Muramatsu T.
    J. Biochem. 112:609-615(1992) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY, GLYCOSYLATION.
    Tissue: Gastric carcinoma.
  2. "The sialomucin CD164 (MGC-24v) is an adhesive glycoprotein expressed by human hematopoietic progenitors and bone marrow stromal cells that serves as a potent negative regulator of hematopoiesis."
    Zannettino A.C.W., Buehring H.-J., Niutta S., Watt S.M., Benton M.A., Simmons P.J.
    Blood 92:2613-2628(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, SUBUNIT, TISSUE SPECIFICITY.
    Tissue: Bone marrow.
  3. "CD164 monoclonal antibodies that block hemopoietic progenitor cell adhesion and proliferation interact with the first mucin domain of the CD164 receptor."
    Doyonnas R., Chan J.Y.-H., Butler L.H., Rappold I., Lee-Prudhoe J.E., Zannettino A.C.W., Simmons P.J., Buehring H.-J., Levesque J.-P., Watt S.M.
    J. Immunol. 165:840-851(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY.
  4. "Relationship between novel isoforms, functionally important domains, and subcellular distribution of CD164/endolyn."
    Chan J.Y.-H., Lee-Prudhoe J.E., Jorgensen B., Ihrke G., Doyonnas R., Zannettino A.C.W., Buckle V.J., Ward C.J., Simmons P.J., Watt S.M.
    J. Biol. Chem. 276:2139-2152(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1; 3 AND 4), ALTERNATIVE SPLICING, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 3; 4 AND 5).
    Tissue: Amygdala, Astrocyte, Neutrophil and Thymus.
  6. "The DNA sequence and analysis of human chromosome 6."
    Mungall A.J., Palmer S.A., Sims S.K., Edwards C.A., Ashurst J.L., Wilming L., Jones M.C., Horton R., Hunt S.E., Scott C.E., Gilbert J.G.R., Clamp M.E., Bethel G., Milne S., Ainscough R., Almeida J.P., Ambrose K.D., Andrews T.D.
    , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beare D.M., Beasley H., Beasley O., Bird C.P., Blakey S.E., Bray-Allen S., Brook J., Brown A.J., Brown J.Y., Burford D.C., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Clark S.Y., Clark G., Clee C.M., Clegg S., Cobley V., Collier R.E., Collins J.E., Colman L.K., Corby N.R., Coville G.J., Culley K.M., Dhami P., Davies J., Dunn M., Earthrowl M.E., Ellington A.E., Evans K.A., Faulkner L., Francis M.D., Frankish A., Frankland J., French L., Garner P., Garnett J., Ghori M.J., Gilby L.M., Gillson C.J., Glithero R.J., Grafham D.V., Grant M., Gribble S., Griffiths C., Griffiths M.N.D., Hall R., Halls K.S., Hammond S., Harley J.L., Hart E.A., Heath P.D., Heathcott R., Holmes S.J., Howden P.J., Howe K.L., Howell G.R., Huckle E., Humphray S.J., Humphries M.D., Hunt A.R., Johnson C.M., Joy A.A., Kay M., Keenan S.J., Kimberley A.M., King A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C.R., Lloyd D.M., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., Maslen G.L., Matthews L., McCann O.T., McLaren S.J., McLay K., McMurray A., Moore M.J.F., Mullikin J.C., Niblett D., Nickerson T., Novik K.L., Oliver K., Overton-Larty E.K., Parker A., Patel R., Pearce A.V., Peck A.I., Phillimore B.J.C.T., Phillips S., Plumb R.W., Porter K.M., Ramsey Y., Ranby S.A., Rice C.M., Ross M.T., Searle S.M., Sehra H.K., Sheridan E., Skuce C.D., Smith S., Smith M., Spraggon L., Squares S.L., Steward C.A., Sycamore N., Tamlyn-Hall G., Tester J., Theaker A.J., Thomas D.W., Thorpe A., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., White S.S., Whitehead S.L., Whittaker H., Wild A., Willey D.J., Wilmer T.E., Wood J.M., Wray P.W., Wyatt J.C., Young L., Younger R.M., Bentley D.R., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Dunham I., Rogers J., Beck S.
    Nature 425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Tissue: Colon.
  9. "The role of sialomucin CD164 (MGC-24v or endolyn) in prostate cancer metastasis."
    Havens A.M., Jung Y., Sun Y.X., Wang J., Shah R.B., Buehring H.J., Pienta K.J., Taichman R.S.
    BMC Cancer 6:195-195(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INDUCTION, TISSUE SPECIFICITY.
  10. "Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells."
    Forde S., Tye B.J., Newey S.E., Roubelakis M., Smythe J., McGuckin C.P., Pettengell R., Watt S.M.
    Blood 109:1825-1833(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH CXCR4.

Entry informationi

Entry nameiMUC24_HUMAN
AccessioniPrimary (citable) accession number: Q04900
Secondary accession number(s): B4DQ85
, E1P5E7, E1P5E8, E1P5E9, O95413, Q5JSU6, Q9BPV0, Q9NR26
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 1, 1994
Last sequence update: September 1, 2009
Last modified: October 29, 2014
This is version 115 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human cell differentiation molecules
    CD nomenclature of surface proteins of human leucocytes and list of entries
  2. Human chromosome 6
    Human chromosome 6: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3