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Q04873 (UDG_SALTY) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 103. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UDP-glucose 6-dehydrogenase

Short name=UDP-Glc dehydrogenase
Short name=UDP-GlcDH
Short name=UDPGDH
EC=1.1.1.22
Gene names
Name:udg
Synonyms:pagA, pmrE
Ordered Locus Names:STM2080
OrganismSalmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) [Reference proteome] [HAMAP]
Taxonomic identifier99287 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeSalmonella

Protein attributes

Sequence length388 AA.
Sequence statusComplete.
Protein existenceInferred from homology

Ontologies

Keywords
   LigandNAD
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processUDP-glucuronate biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

lipopolysaccharide biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionNAD binding

Inferred from electronic annotation. Source: InterPro

UDP-glucose 6-dehydrogenase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 388388UDP-glucose 6-dehydrogenase
PRO_0000074047

Regions

Nucleotide binding2 – 1918NAD Potential

Sites

Active site2531 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q04873 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: 04184EEE5DAA80F7

FASTA38843,634
        10         20         30         40         50         60 
MKITISGTGY VGLSNGLLIA QHHDVVALDI VPSRVELLND RISPIVDKEI QQFLKEDNIR 

        70         80         90        100        110        120 
FRATLDKFDA YQNADYVIIA TPTDYDPKTN YFNTSSVESV MQDVISINPA AVMIIKSTVP 

       130        140        150        160        170        180 
VGFTAAMRQK FATENIIFSP EFLREGKALY DNLYPSRIVI GEQSERAREF AALLQEGAIK 

       190        200        210        220        230        240 
QEIPTLFTDS TEAEAIKLFA NTYLAMRVAY FNELDSYAET LGLNTRQIIE GVCLDPRIGN 

       250        260        270        280        290        300 
HYNNPSFGYG GYCLPKDTKQ LLANYQSVPN NIISAIVEAN RTRKDFIADA ILARKPKVVG 

       310        320        330        340        350        360 
IYRLIMKSGS DNFRASSIQG IMKRIKAKGV EVIIYEPVME EDTFFNSRLE RDLHCFKQQA 

       370        380 
DVIISNRMAA ELLDVAEKVY TRDLFGSD 

« Hide

References

« Hide 'large scale' references
[1]"Repeat unit polysaccharides of bacteria: a model for polymerization resembling that of ribosomes and fatty acid synthetase, with a novel mechanism for determining chain length."
Bastin D.A., Stevenson G., Brown P.K., Haase A., Reeves P.R.
Mol. Microbiol. 7:725-734(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: LT2.
[2]"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2."
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. expand/collapse author list , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.
Nature 413:852-856(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: LT2 / SGSC1412 / ATCC 700720.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z17278 Genomic DNA. Translation: CAA78945.1.
AE006468 Genomic DNA. Translation: AAL20984.1.
RefSeqNP_461025.1. NC_003197.1.

3D structure databases

ProteinModelPortalQ04873.
SMRQ04873. Positions 1-388.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING99287.STM2080.

Proteomic databases

PaxDbQ04873.
PRIDEQ04873.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAL20984; AAL20984; STM2080.
GeneID1253601.
KEGGstm:STM2080.
PATRIC32382743. VBISalEnt20916_2202.

Phylogenomic databases

eggNOGCOG1004.
HOGENOMHOG000280378.
KOK00012.
OMAVIVANRY.
OrthoDBEOG61CM1K.
PhylomeDBQ04873.

Enzyme and pathway databases

BioCycSENT99287:GCTI-2092-MONOMER.
UniPathwayUPA00030.
UPA00038; UER00491.

Family and domain databases

Gene3D1.10.1040.10. 1 hit.
3.40.50.720. 2 hits.
InterProIPR008927. 6-PGluconate_DH_C-like.
IPR013328. DH_multihelical.
IPR016040. NAD(P)-bd_dom.
IPR017476. UDP-Glc/GDP-Man.
IPR014027. UDP-Glc/GDP-Man_DH_C.
IPR014026. UDP-Glc/GDP-Man_DH_dimer.
IPR001732. UDP-Glc/GDP-Man_DH_N.
IPR028357. UDPglc_DH_bac.
[Graphical view]
PANTHERPTHR11374. PTHR11374. 1 hit.
PfamPF00984. UDPG_MGDP_dh. 1 hit.
PF03720. UDPG_MGDP_dh_C. 1 hit.
PF03721. UDPG_MGDP_dh_N. 1 hit.
[Graphical view]
PIRSFPIRSF500134. UDPglc_DH_bac. 1 hit.
PIRSF000124. UDPglc_GDPman_dh. 1 hit.
SMARTSM00984. UDPG_MGDP_dh_C. 1 hit.
[Graphical view]
SUPFAMSSF48179. SSF48179. 1 hit.
SSF52413. SSF52413. 1 hit.
TIGRFAMsTIGR03026. NDP-sugDHase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUDG_SALTY
AccessionPrimary (citable) accession number: Q04873
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: July 9, 2014
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways