ID   YM94_YEAST              Reviewed;         349 AA.
AC   Q04869; D6W0E2;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   27-MAR-2024, entry version 154.
DE   RecName: Full=Uncharacterized protein YMR315W;
GN   OrderedLocusNames=YMR315W; ORFNames=YM9924.07;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169872;
RA   Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA   Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA   Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA   Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL   Nature 387:90-93(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX   PubMed=14562106; DOI=10.1038/nature02046;
RA   Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA   O'Shea E.K., Weissman J.S.;
RT   "Global analysis of protein expression in yeast.";
RL   Nature 425:737-741(2003).
RN   [5]
RP   PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-2, AND IDENTIFICATION BY MASS
RP   SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA   Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT   "A multidimensional chromatography technology for in-depth phosphoproteome
RT   analysis.";
RL   Mol. Cell. Proteomics 7:1389-1396(2008).
RN   [6]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX   PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA   Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA   Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA   Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT   "N-terminal acetylome analyses and functional insights of the N-terminal
RT   acetyltransferase NatB.";
RL   Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC   -!- MISCELLANEOUS: Present with 9600 molecules/cell in log phase SD medium.
CC       {ECO:0000269|PubMed:14562106}.
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DR   EMBL; Z54141; CAA90833.1; -; Genomic_DNA.
DR   EMBL; AY557991; AAS56317.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA10216.1; -; Genomic_DNA.
DR   PIR; S59308; S59308.
DR   RefSeq; NP_014046.1; NM_001182826.1.
DR   AlphaFoldDB; Q04869; -.
DR   SMR; Q04869; -.
DR   BioGRID; 35495; 111.
DR   DIP; DIP-3844N; -.
DR   IntAct; Q04869; 13.
DR   MINT; Q04869; -.
DR   STRING; 4932.YMR315W; -.
DR   iPTMnet; Q04869; -.
DR   MaxQB; Q04869; -.
DR   PaxDb; 4932-YMR315W; -.
DR   PeptideAtlas; Q04869; -.
DR   TopDownProteomics; Q04869; -.
DR   EnsemblFungi; YMR315W_mRNA; YMR315W; YMR315W.
DR   GeneID; 855363; -.
DR   KEGG; sce:YMR315W; -.
DR   AGR; SGD:S000004932; -.
DR   SGD; S000004932; YMR315W.
DR   VEuPathDB; FungiDB:YMR315W; -.
DR   eggNOG; KOG2742; Eukaryota.
DR   HOGENOM; CLU_023194_3_1_1; -.
DR   InParanoid; Q04869; -.
DR   OMA; IWVGMDE; -.
DR   OrthoDB; 1354046at2759; -.
DR   BioCyc; YEAST:G3O-32979-MONOMER; -.
DR   BioGRID-ORCS; 855363; 0 hits in 10 CRISPR screens.
DR   PRO; PR:Q04869; -.
DR   Proteomes; UP000002311; Chromosome XIII.
DR   RNAct; Q04869; Protein.
DR   GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR   GO; GO:0005634; C:nucleus; HDA:SGD.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IDA:SGD.
DR   GO; GO:0006740; P:NADPH regeneration; IGI:SGD.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR004104; Gfo/Idh/MocA-like_OxRdtase_C.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42840:SF5; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR42840; NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN-RELATED; 1.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   Pfam; PF02894; GFO_IDH_MocA_C; 1.
DR   SUPFAM; SSF55347; Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   1: Evidence at protein level;
KW   Phosphoprotein; Reference proteome.
FT   CHAIN           1..349
FT                   /note="Uncharacterized protein YMR315W"
FT                   /id="PRO_0000203357"
FT   MOD_RES         2
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0007744|PubMed:18407956"
SQ   SEQUENCE   349 AA;  38216 MW;  77C7F72321BCAD1F CRC64;
     MSPLNVGIVG TGIFARDRHL PSYQEFPDKF KVIAAFNRHK AKALDFAKVA DIPENKVYDN
     LDEILNDPHV DYIDALLPAQ FNADIVEKAV KAGKPVILEK PIAANLDQAK EIVKIAESTP
     LPVGVAENWL YLPCIKIAKE QIEKIGPVVA FTHNSTGPFV TQNKYLTTTW RQKPEHIGGF
     LSDGGVHQLA LVISLLGEFG SVSALTRQVR ERSGADDIVF ATVQLKNKEV IGSFTYGSAF
     GATEKSVFLK VYGKNGTVTV DLSDKKDPVV KVKLGGSAED NGDEQIFKVD NDESFGVNAE
     FLNFHEAVSK KDKSLYLGTP RTAFHHLACV DAFLKSSAKN GDYVKIEQP
//