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Protein

Non-structural protein of 12.9 kDa

Gene

5a

Organism
Human coronavirus OC43 (HCoV-OC43)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

May act as membrane-anchoring region for structural proteins during virus assembly, or play a role in membrane association of the viral polymerase during replication.

Protein family/group databases

TCDBi1.A.49.1.1. the human coronavirus ns12,9 viroporin (ns12,9) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Non-structural protein of 12.9 kDa
Short name:
ns12.9
Alternative name(s):
12.9 kDa accessory protein
NS2
Gene namesi
ORF Names:5a
OrganismiHuman coronavirus OC43 (HCoV-OC43)
Taxonomic identifieri31631 [NCBI]
Taxonomic lineageiVirusesssRNA virusesssRNA positive-strand viruses, no DNA stageNidoviralesCoronaviridaeCoronavirinaeBetacoronavirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000100580 Componenti: Genome
  • UP000007552 Componenti: Genome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001060651 – 109Non-structural protein of 12.9 kDaAdd BLAST109

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

OrthoDBiVOG09000177.

Family and domain databases

InterProiView protein in InterPro
IPR006841. Corona_NS2.
PfamiView protein in Pfam
PF04753. Corona_NS2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04853-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDIWRPEKKY LRYINGFNVS ELEDACFKFN YQFPKVGYCR VPSHAWCRNQ
60 70 80 90 100
GRFCATFTLY GKSKHYDKYF GVINGFTAFA NTVEDAVNKL VFLAVDFITW

RRQELNVYG
Length:109
Mass (Da):12,935
Last modified:February 1, 1994 - v1
Checksum:i8F06A6E9E30B1667
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M99576 Genomic RNA. Translation: AAA02569.1.
AY585228 Genomic RNA. Translation: AAT84355.1.
AY585229 Genomic RNA. Translation: AAT84363.1.
AY391777 Genomic RNA. Translation: AAR01016.1.
PIRiA44275.

Similar proteinsi

Entry informationi

Entry nameiNS12_CVHOC
AccessioniPrimary (citable) accession number: Q04853
Secondary accession number(s): Q696P7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: March 15, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome