Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q04835

- YM87_YEAST

UniProt

Q04835 - YM87_YEAST

Protein

Uncharacterized membrane protein YMR253C

Gene

YMR253C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32930-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized membrane protein YMR253C
    Gene namesi
    Ordered Locus Names:YMR253C
    ORF Names:YM9920.07C
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYMR253c.
    SGDiS000004866. YMR253C.

    Subcellular locationi

    Membrane 1 Publication; Multi-pass membrane protein 1 Publication
    Note: Localizes to cytoplasmic punctate structures.

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 414414Uncharacterized membrane protein YMR253CPRO_0000203340Add
    BLAST

    Proteomic databases

    MaxQBiQ04835.
    PaxDbiQ04835.

    Expressioni

    Gene expression databases

    GenevestigatoriQ04835.

    Interactioni

    Protein-protein interaction databases

    BioGridi35432. 9 interactions.
    DIPiDIP-5067N.
    IntActiQ04835. 4 interactions.
    MINTiMINT-563831.
    STRINGi4932.YMR253C.

    Structurei

    3D structure databases

    ProteinModelPortaliQ04835.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 6666LumenalSequence AnalysisAdd
    BLAST
    Topological domaini88 – 10619CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini128 – 14417LumenalSequence AnalysisAdd
    BLAST
    Topological domaini168 – 1714CytoplasmicSequence Analysis
    Topological domaini192 – 1998LumenalSequence Analysis
    Topological domaini221 – 24121CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini263 – 2697LumenalSequence Analysis
    Topological domaini291 – 30717CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini329 – 35729LumenalSequence AnalysisAdd
    BLAST
    Topological domaini379 – 41436CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei67 – 8721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei107 – 12721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei145 – 16723HelicalSequence AnalysisAdd
    BLAST
    Transmembranei172 – 19120HelicalSequence AnalysisAdd
    BLAST
    Transmembranei200 – 22021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei242 – 26221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei270 – 29021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei308 – 32821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei358 – 37821HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini78 – 215138EamA 1Add
    BLAST
    Domaini253 – 379127EamA 2Add
    BLAST

    Sequence similaritiesi

    Contains 2 EamA domains.Curated
    To yeast YPL264c.Curated

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG0697.
    GeneTreeiENSGT00730000111035.
    HOGENOMiHOG000248677.
    OMAiAFIAWVA.
    OrthoDBiEOG744TKH.

    Family and domain databases

    InterProiIPR000620. DMT.
    [Graphical view]
    PfamiPF00892. EamA. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04835-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNPSVPKVMK RENNTHLLVS KEMNDTSLQL PSTTRSLSPK ESNSNEDFNV    50
    DGNETTLQRI SKDYLKPNIG LVLLTVSYFF NSAMVVSTKV LENDPDDIAN 100
    DRQIKPLQIL LVRMVITYIG TLIYMYINKS TISDVPFGKP EVRKWLVLRG 150
    CTGFFGVFGM YYSLMYLTIS DAVLITFLAP SLTIFLSWVI LRERFTKVEA 200
    LGSLISLLGV VLIVRPSFLF GTPELTDSSS QIVESSDPKS RLIATLVGLW 250
    GVLGMSCVYI IIRYIGKRAH AIMSVSYFSL ITAIVSFIGI NTIPSMKFQI 300
    PHSKKQWILF GNLGVSGFIF QLLLTMGIQR ERAGRGSLMT YTQLLYAVFW 350
    DVALYKHWPN IWSWIGMIII ISATLWVIRI RAANNETTAK DLTPIIDDEE 400
    NSIPLTEFDL SDSK 414
    Length:414
    Mass (Da):46,659
    Last modified:November 1, 1997 - v1
    Checksum:iE0EBD0F3BE4CC8AB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti278 – 2781F → L in AAU09774. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48639 Genomic DNA. Translation: CAA88580.1.
    AY723857 Genomic DNA. Translation: AAU09774.1.
    BK006946 Genomic DNA. Translation: DAA10154.1.
    PIRiS53075.
    RefSeqiNP_013980.1. NM_001182760.1.

    Genome annotation databases

    EnsemblFungiiYMR253C; YMR253C; YMR253C.
    GeneIDi855295.
    KEGGisce:YMR253C.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z48639 Genomic DNA. Translation: CAA88580.1 .
    AY723857 Genomic DNA. Translation: AAU09774.1 .
    BK006946 Genomic DNA. Translation: DAA10154.1 .
    PIRi S53075.
    RefSeqi NP_013980.1. NM_001182760.1.

    3D structure databases

    ProteinModelPortali Q04835.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35432. 9 interactions.
    DIPi DIP-5067N.
    IntActi Q04835. 4 interactions.
    MINTi MINT-563831.
    STRINGi 4932.YMR253C.

    Proteomic databases

    MaxQBi Q04835.
    PaxDbi Q04835.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YMR253C ; YMR253C ; YMR253C .
    GeneIDi 855295.
    KEGGi sce:YMR253C.

    Organism-specific databases

    CYGDi YMR253c.
    SGDi S000004866. YMR253C.

    Phylogenomic databases

    eggNOGi COG0697.
    GeneTreei ENSGT00730000111035.
    HOGENOMi HOG000248677.
    OMAi AFIAWVA.
    OrthoDBi EOG744TKH.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32930-MONOMER.

    Miscellaneous databases

    NextBioi 978952.

    Gene expression databases

    Genevestigatori Q04835.

    Family and domain databases

    InterProi IPR000620. DMT.
    [Graphical view ]
    Pfami PF00892. EamA. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
    5. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.
    6. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
      Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
      Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    7. "Sites of ubiquitin attachment in Saccharomyces cerevisiae."
      Starita L.M., Lo R.S., Eng J.K., von Haller P.D., Fields S.
      Proteomics 12:236-240(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiYM87_YEAST
    AccessioniPrimary (citable) accession number: Q04835
    Secondary accession number(s): D6W080, Q66R30
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3