Q04833 (LRP_CAEEL) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 112.
History...
Clusters with 
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Low-density lipoprotein receptor-related protein Short name=LRP | ||||
| Gene names |
| ||||
| Organism | Caenorhabditis elegans [Reference proteome] | ||||
| Taxonomic identifier | 6239 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis |
Protein attributes
| Sequence length | 4753 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is further processed into a mature form. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | May act as a receptor for the endocytosis of extracellular ligands such as chylomicron remnants, protease-inhibitor complexes and vitellogenin. |
| Subcellular location | Membrane; Single-pass type I membrane protein. Membrane › coated pit. |
| Sequence similarities | Belongs to the LDLR family. Contains 17 EGF-like domains. Contains 35 LDL-receptor class A domains. Contains 30 LDL-receptor class B repeats. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||||
Molecule processing | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal peptide | 1 – 18 | 18 | Potential | ||||||||
| Chain | 19 – 4753 | 4735 | Low-density lipoprotein receptor-related protein | PRO_0000017341 | |||||||
Regions | |||||||||||
| Topological domain | 19 – 4570 | 4552 | Extracellular Potential | ||||||||
| Transmembrane | 4571 – 4596 | 26 | Helical; Potential | ||||||||
| Topological domain | 4597 – 4753 | 157 | Cytoplasmic Potential | ||||||||
| Domain | 51 – 89 | 39 | LDL-receptor class A 1 | ||||||||
| Domain | 90 – 133 | 44 | LDL-receptor class A 2 | ||||||||
| Domain | 136 – 177 | 42 | LDL-receptor class A 3 | ||||||||
| Domain | 180 – 220 | 41 | LDL-receptor class A 4 | ||||||||
| Domain | 221 – 259 | 39 | LDL-receptor class A 5 | ||||||||
| Domain | 260 – 298 | 39 | LDL-receptor class A 6 | ||||||||
| Domain | 299 – 337 | 39 | EGF-like 1 | ||||||||
| Domain | 338 – 368 | 31 | EGF-like 2; calcium-binding Potential | ||||||||
| Repeat | 436 – 482 | 47 | LDL-receptor class B 1 | ||||||||
| Repeat | 483 – 525 | 43 | LDL-receptor class B 2 | ||||||||
| Repeat | 526 – 566 | 41 | LDL-receptor class B 3 | ||||||||
| Repeat | 567 – 609 | 43 | LDL-receptor class B 4 | ||||||||
| Repeat | 610 – 654 | 45 | LDL-receptor class B 5 | ||||||||
| Domain | 669 – 712 | 44 | EGF-like 3 | ||||||||
| Repeat | 766 – 808 | 43 | LDL-receptor class B 6 | ||||||||
| Repeat | 809 – 858 | 50 | LDL-receptor class B 7 | ||||||||
| Repeat | 859 – 902 | 44 | LDL-receptor class B 8 | ||||||||
| Repeat | 903 – 944 | 42 | LDL-receptor class B 9 | ||||||||
| Domain | 997 – 1043 | 47 | EGF-like 4 | ||||||||
| Domain | 1052 – 1097 | 46 | LDL-receptor class A 7 | ||||||||
| Domain | 1099 – 1140 | 42 | LDL-receptor class A 8 | ||||||||
| Domain | 1144 – 1184 | 41 | LDL-receptor class A 9 | ||||||||
| Domain | 1185 – 1225 | 41 | LDL-receptor class A 10 | ||||||||
| Domain | 1226 – 1265 | 40 | LDL-receptor class A 11 | ||||||||
| Domain | 1268 – 1309 | 42 | LDL-receptor class A 12 | ||||||||
| Domain | 1311 – 1352 | 42 | LDL-receptor class A 13 | ||||||||
| Domain | 1357 – 1397 | 41 | LDL-receptor class A 14 | ||||||||
| Domain | 1398 – 1436 | 39 | EGF-like 5 | ||||||||
| Domain | 1437 – 1476 | 40 | EGF-like 6 | ||||||||
| Repeat | 1524 – 1566 | 43 | LDL-receptor class B 10 | ||||||||
| Repeat | 1567 – 1610 | 44 | LDL-receptor class B 11 | ||||||||
| Repeat | 1611 – 1654 | 44 | LDL-receptor class B 12 | ||||||||
| Repeat | 1655 – 1699 | 45 | LDL-receptor class B 13 | ||||||||
| Domain | 1747 – 1786 | 40 | EGF-like 7 | ||||||||
| Repeat | 1894 – 1942 | 49 | LDL-receptor class B 14 | ||||||||
| Repeat | 1943 – 1989 | 47 | LDL-receptor class B 15 | ||||||||
| Repeat | 1990 – 2032 | 43 | LDL-receptor class B 16 | ||||||||
| Domain | 2080 – 2120 | 41 | EGF-like 8 | ||||||||
| Repeat | 2215 – 2259 | 45 | LDL-receptor class B 17 | ||||||||
| Repeat | 2260 – 2303 | 44 | LDL-receptor class B 18 | ||||||||
| Repeat | 2304 – 2345 | 42 | LDL-receptor class B 19 | ||||||||
| Domain | 2396 – 2439 | 44 | EGF-like 9 | ||||||||
| Repeat | 2582 – 2632 | 51 | LDL-receptor class B 20 | ||||||||
| Repeat | 2633 – 2675 | 43 | LDL-receptor class B 21 | ||||||||
| Domain | 2728 – 2780 | 53 | EGF-like 10 | ||||||||
| Domain | 2790 – 2831 | 42 | LDL-receptor class A 15 | ||||||||
| Domain | 2832 – 2870 | 39 | LDL-receptor class A 16 | ||||||||
| Domain | 2872 – 2914 | 43 | LDL-receptor class A 17 | ||||||||
| Domain | 2917 – 2958 | 42 | LDL-receptor class A 18 | ||||||||
| Domain | 2959 – 2999 | 41 | LDL-receptor class A 19 | ||||||||
| Domain | 3004 – 3046 | 43 | LDL-receptor class A 20 | ||||||||
| Domain | 3047 – 3095 | 49 | LDL-receptor class A 21 | ||||||||
| Domain | 3098 – 3137 | 40 | LDL-receptor class A 22 | ||||||||
| Domain | 3138 – 3176 | 39 | LDL-receptor class A 23 | ||||||||
| Domain | 3185 – 3223 | 39 | LDL-receptor class A 24 | ||||||||
| Domain | 3224 – 3265 | 42 | EGF-like 11 | ||||||||
| Domain | 3266 – 3306 | 41 | EGF-like 12; calcium-binding Potential | ||||||||
| Repeat | 3354 – 3401 | 48 | LDL-receptor class B 22 | ||||||||
| Repeat | 3402 – 3444 | 43 | LDL-receptor class B 23 | ||||||||
| Repeat | 3445 – 3493 | 49 | LDL-receptor class B 24 | ||||||||
| Repeat | 3494 – 3536 | 43 | LDL-receptor class B 25 | ||||||||
| Repeat | 3537 – 3577 | 41 | LDL-receptor class B 26 | ||||||||
| Domain | 3582 – 3624 | 43 | EGF-like 13 | ||||||||
| Domain | 3625 – 3668 | 44 | LDL-receptor class A 25 | ||||||||
| Domain | 3669 – 3707 | 39 | LDL-receptor class A 26 | ||||||||
| Domain | 3707 – 3748 | 42 | LDL-receptor class A 27 | ||||||||
| Domain | 3751 – 3790 | 40 | LDL-receptor class A 28 | ||||||||
| Domain | 3791 – 3832 | 42 | LDL-receptor class A 29 | ||||||||
| Domain | 3831 – 3873 | 43 | LDL-receptor class A 30 | ||||||||
| Domain | 3876 – 3914 | 39 | LDL-receptor class A 31 | ||||||||
| Domain | 3915 – 3953 | 39 | LDL-receptor class A 32 | ||||||||
| Domain | 3957 – 3997 | 41 | LDL-receptor class A 33 | ||||||||
| Domain | 3998 – 4042 | 45 | LDL-receptor class A 34 | ||||||||
| Domain | 4047 – 4085 | 39 | LDL-receptor class A 35 | ||||||||
| Domain | 4088 – 4131 | 44 | EGF-like 14 | ||||||||
| Domain | 4132 – 4176 | 45 | EGF-like 15; calcium-binding Potential | ||||||||
| Repeat | 4227 – 4276 | 50 | LDL-receptor class B 27 | ||||||||
| Repeat | 4343 – 4386 | 44 | LDL-receptor class B 28 | ||||||||
| Repeat | 4388 – 4429 | 42 | LDL-receptor class B 29 | ||||||||
| Repeat | 4430 – 4470 | 41 | LDL-receptor class B 30 | ||||||||
| Domain | 4477 – 4515 | 39 | EGF-like 16 | ||||||||
| Domain | 4526 – 4554 | 29 | EGF-like 17 | ||||||||
| Motif | 4653 – 4658 | 6 | Endocytosis signal Potential | ||||||||
Sites | |||||||||||
| Site | 4744 | 1 | Critical for endocytosis By similarity | ||||||||
Amino acid modifications | |||||||||||
| Glycosylation | 17 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 118 | 1 | N-linked (GlcNAc...) Ref.3 Ref.5 | ||||||||
| Glycosylation | 178 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 380 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 887 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 1039 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 1057 | 1 | N-linked (GlcNAc...) Ref.4 | ||||||||
| Glycosylation | 1184 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 1431 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 1542 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 1545 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 1597 | 1 | N-linked (GlcNAc...) Ref.4 Ref.5 | ||||||||
| Glycosylation | 1718 | 1 | N-linked (GlcNAc...) Ref.4 Ref.5 | ||||||||
| Glycosylation | 1871 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 2364 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 2501 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 2762 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 2888 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 2996 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 3046 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 3134 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 3557 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 3626 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 3682 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 3752 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 4063 | 1 | N-linked (GlcNAc...) Ref.5 | ||||||||
| Glycosylation | 4139 | 1 | N-linked (GlcNAc...) Potential | ||||||||
| Glycosylation | 4248 | 1 | N-linked (GlcNAc...) Ref.4 | ||||||||
| Disulfide bond | 53 ↔ 65 | By similarity | |||||||||
| Disulfide bond | 60 ↔ 78 | By similarity | |||||||||
| Disulfide bond | 72 ↔ 87 | By similarity | |||||||||
| Disulfide bond | 92 ↔ 109 | By similarity | |||||||||
| Disulfide bond | 99 ↔ 122 | By similarity | |||||||||
| Disulfide bond | 116 ↔ 131 | By similarity | |||||||||
| Disulfide bond | 138 ↔ 152 | By similarity | |||||||||
| Disulfide bond | 146 ↔ 165 | By similarity | |||||||||
| Disulfide bond | 159 ↔ 175 | By similarity | |||||||||
| Disulfide bond | 182 ↔ 195 | By similarity | |||||||||
| Disulfide bond | 189 ↔ 208 | By similarity | |||||||||
| Disulfide bond | 202 ↔ 218 | By similarity | |||||||||
| Disulfide bond | 223 ↔ 235 | By similarity | |||||||||
| Disulfide bond | 230 ↔ 248 | By similarity | |||||||||
| Disulfide bond | 242 ↔ 257 | By similarity | |||||||||
| Disulfide bond | 262 ↔ 275 | By similarity | |||||||||
| Disulfide bond | 269 ↔ 288 | By similarity | |||||||||
| Disulfide bond | 282 ↔ 297 | By similarity | |||||||||
| Disulfide bond | 302 ↔ 311 | By similarity | |||||||||
| Disulfide bond | 307 ↔ 320 | By similarity | |||||||||
| Disulfide bond | 322 ↔ 336 | By similarity | |||||||||
| Disulfide bond | 342 ↔ 352 | By similarity | |||||||||
| Disulfide bond | 348 ↔ 361 | By similarity | |||||||||
| Disulfide bond | 363 ↔ 367 | By similarity | |||||||||
| Disulfide bond | 673 ↔ 682 | By similarity | |||||||||
| Disulfide bond | 678 ↔ 697 | By similarity | |||||||||
| Disulfide bond | 699 ↔ 711 | By similarity | |||||||||
| Disulfide bond | 1001 ↔ 1010 | By similarity | |||||||||
| Disulfide bond | 1006 ↔ 1026 | By similarity | |||||||||
| Disulfide bond | 1028 ↔ 1042 | By similarity | |||||||||
| Disulfide bond | 1054 ↔ 1068 | By similarity | |||||||||
| Disulfide bond | 1063 ↔ 1081 | By similarity | |||||||||
| Disulfide bond | 1075 ↔ 1095 | By similarity | |||||||||
| Disulfide bond | 1101 ↔ 1114 | By similarity | |||||||||
| Disulfide bond | 1108 ↔ 1127 | By similarity | |||||||||
| Disulfide bond | 1121 ↔ 1138 | By similarity | |||||||||
| Disulfide bond | 1146 ↔ 1158 | By similarity | |||||||||
| Disulfide bond | 1153 ↔ 1171 | By similarity | |||||||||
| Disulfide bond | 1165 ↔ 1182 | By similarity | |||||||||
| Disulfide bond | 1187 ↔ 1199 | By similarity | |||||||||
| Disulfide bond | 1194 ↔ 1212 | By similarity | |||||||||
| Disulfide bond | 1206 ↔ 1223 | By similarity | |||||||||
| Disulfide bond | 1228 ↔ 1241 | By similarity | |||||||||
| Disulfide bond | 1235 ↔ 1254 | By similarity | |||||||||
| Disulfide bond | 1248 ↔ 1263 | By similarity | |||||||||
| Disulfide bond | 1270 ↔ 1283 | By similarity | |||||||||
| Disulfide bond | 1277 ↔ 1296 | By similarity | |||||||||
| Disulfide bond | 1290 ↔ 1307 | By similarity | |||||||||
| Disulfide bond | 1313 ↔ 1325 | By similarity | |||||||||
| Disulfide bond | 1320 ↔ 1338 | By similarity | |||||||||
| Disulfide bond | 1332 ↔ 1350 | By similarity | |||||||||
| Disulfide bond | 1359 ↔ 1373 | By similarity | |||||||||
| Disulfide bond | 1366 ↔ 1386 | By similarity | |||||||||
| Disulfide bond | 1380 ↔ 1396 | By similarity | |||||||||
| Disulfide bond | 1401 ↔ 1412 | By similarity | |||||||||
| Disulfide bond | 1408 ↔ 1421 | By similarity | |||||||||
| Disulfide bond | 1423 ↔ 1435 | By similarity | |||||||||
| Disulfide bond | 1441 ↔ 1451 | By similarity | |||||||||
| Disulfide bond | 1447 ↔ 1460 | By similarity | |||||||||
| Disulfide bond | 1462 ↔ 1475 | By similarity | |||||||||
| Disulfide bond | 1751 ↔ 1760 | By similarity | |||||||||
| Disulfide bond | 1756 ↔ 1770 | By similarity | |||||||||
| Disulfide bond | 1772 ↔ 1785 | By similarity | |||||||||
| Disulfide bond | 2084 ↔ 2095 | By similarity | |||||||||
| Disulfide bond | 2091 ↔ 2105 | By similarity | |||||||||
| Disulfide bond | 2107 ↔ 2119 | By similarity | |||||||||
| Disulfide bond | 2400 ↔ 2415 | By similarity | |||||||||
| Disulfide bond | 2411 ↔ 2426 | By similarity | |||||||||
| Disulfide bond | 2428 ↔ 2438 | By similarity | |||||||||
| Disulfide bond | 2732 ↔ 2743 | By similarity | |||||||||
| Disulfide bond | 2739 ↔ 2759 | By similarity | |||||||||
| Disulfide bond | 2761 ↔ 2779 | By similarity | |||||||||
| Disulfide bond | 2792 ↔ 2805 | By similarity | |||||||||
| Disulfide bond | 2800 ↔ 2818 | By similarity | |||||||||
| Disulfide bond | 2812 ↔ 2829 | By similarity | |||||||||
| Disulfide bond | 2834 ↔ 2846 | By similarity | |||||||||
| Disulfide bond | 2841 ↔ 2859 | By similarity | |||||||||
| Disulfide bond | 2853 ↔ 2868 | By similarity | |||||||||
| Disulfide bond | 2874 ↔ 2886 | By similarity | |||||||||
| Disulfide bond | 2881 ↔ 2899 | By similarity | |||||||||
| Disulfide bond | 2893 ↔ 2912 | By similarity | |||||||||
| Disulfide bond | 2919 ↔ 2932 | By similarity | |||||||||
| Disulfide bond | 2926 ↔ 2945 | By similarity | |||||||||
| Disulfide bond | 2939 ↔ 2956 | By similarity | |||||||||
| Disulfide bond | 2961 ↔ 2973 | By similarity | |||||||||
| Disulfide bond | 2968 ↔ 2986 | By similarity | |||||||||
| Disulfide bond | 2980 ↔ 2997 | By similarity | |||||||||
| Disulfide bond | 3006 ↔ 3019 | By similarity | |||||||||
| Disulfide bond | 3014 ↔ 3032 | By similarity | |||||||||
| Disulfide bond | 3026 ↔ 3044 | By similarity | |||||||||
| Disulfide bond | 3049 ↔ 3069 | By similarity | |||||||||
| Disulfide bond | 3056 ↔ 3082 | By similarity | |||||||||
| Disulfide bond | 3076 ↔ 3093 | By similarity | |||||||||
| Disulfide bond | 3100 ↔ 3112 | By similarity | |||||||||
| Disulfide bond | 3107 ↔ 3125 | By similarity | |||||||||
| Disulfide bond | 3119 ↔ 3135 | By similarity | |||||||||
| Disulfide bond | 3140 ↔ 3152 | By similarity | |||||||||
| Disulfide bond | 3147 ↔ 3165 | By similarity | |||||||||
| Disulfide bond | 3159 ↔ 3174 | By similarity | |||||||||
| Disulfide bond | 3187 ↔ 3199 | By similarity | |||||||||
| Disulfide bond | 3194 ↔ 3212 | By similarity | |||||||||
| Disulfide bond | 3206 ↔ 3222 | By similarity | |||||||||
| Disulfide bond | 3227 ↔ 3239 | By similarity | |||||||||
| Disulfide bond | 3235 ↔ 3248 | By similarity | |||||||||
| Disulfide bond | 3250 ↔ 3264 | By similarity | |||||||||
| Disulfide bond | 3270 ↔ 3281 | By similarity | |||||||||
| Disulfide bond | 3277 ↔ 3290 | By similarity | |||||||||
| Disulfide bond | 3292 ↔ 3305 | By similarity | |||||||||
| Disulfide bond | 3586 ↔ 3597 | By similarity | |||||||||
| Disulfide bond | 3593 ↔ 3608 | By similarity | |||||||||
| Disulfide bond | 3610 ↔ 3623 | By similarity | |||||||||
| Disulfide bond | 3627 ↔ 3641 | By similarity | |||||||||
| Disulfide bond | 3634 ↔ 3654 | By similarity | |||||||||
| Disulfide bond | 3648 ↔ 3666 | By similarity | |||||||||
| Disulfide bond | 3671 ↔ 3683 | By similarity | |||||||||
| Disulfide bond | 3678 ↔ 3696 | By similarity | |||||||||
| Disulfide bond | 3690 ↔ 3705 | By similarity | |||||||||
| Disulfide bond | 3709 ↔ 3722 | By similarity | |||||||||
| Disulfide bond | 3716 ↔ 3735 | By similarity | |||||||||
| Disulfide bond | 3729 ↔ 3746 | By similarity | |||||||||
| Disulfide bond | 3753 ↔ 3765 | By similarity | |||||||||
| Disulfide bond | 3760 ↔ 3778 | By similarity | |||||||||
| Disulfide bond | 3772 ↔ 3788 | By similarity | |||||||||
| Disulfide bond | 3793 ↔ 3806 | By similarity | |||||||||
| Disulfide bond | 3800 ↔ 3819 | By similarity | |||||||||
| Disulfide bond | 3813 ↔ 3830 | By similarity | |||||||||
| Disulfide bond | 3833 ↔ 3847 | By similarity | |||||||||
| Disulfide bond | 3841 ↔ 3860 | By similarity | |||||||||
| Disulfide bond | 3854 ↔ 3871 | By similarity | |||||||||
| Disulfide bond | 3878 ↔ 3890 | By similarity | |||||||||
| Disulfide bond | 3885 ↔ 3903 | By similarity | |||||||||
| Disulfide bond | 3897 ↔ 3912 | By similarity | |||||||||
| Disulfide bond | 3917 ↔ 3929 | By similarity | |||||||||
| Disulfide bond | 3924 ↔ 3942 | By similarity | |||||||||
| Disulfide bond | 3936 ↔ 3951 | By similarity | |||||||||
| Disulfide bond | 3959 ↔ 3971 | By similarity | |||||||||
| Disulfide bond | 3966 ↔ 3984 | By similarity | |||||||||
| Disulfide bond | 3978 ↔ 3995 | By similarity | |||||||||
| Disulfide bond | 4000 ↔ 4014 | By similarity | |||||||||
| Disulfide bond | 4008 ↔ 4027 | By similarity | |||||||||
| Disulfide bond | 4021 ↔ 4040 | By similarity | |||||||||
| Disulfide bond | 4049 ↔ 4061 | By similarity | |||||||||
| Disulfide bond | 4056 ↔ 4074 | By similarity | |||||||||
| Disulfide bond | 4068 ↔ 4083 | By similarity | |||||||||
| Disulfide bond | 4092 ↔ 4105 | By similarity | |||||||||
| Disulfide bond | 4101 ↔ 4114 | By similarity | |||||||||
| Disulfide bond | 4116 ↔ 4130 | By similarity | |||||||||
| Disulfide bond | 4136 ↔ 4146 | By similarity | |||||||||
| Disulfide bond | 4142 ↔ 4155 | By similarity | |||||||||
| Disulfide bond | 4157 ↔ 4175 | By similarity | |||||||||
| Disulfide bond | 4481 ↔ 4490 | By similarity | |||||||||
| Disulfide bond | 4486 ↔ 4500 | By similarity | |||||||||
| Disulfide bond | 4502 ↔ 4514 | By similarity | |||||||||
| Disulfide bond | 4528 ↔ 4536 | By similarity | |||||||||
| Disulfide bond | 4530 ↔ 4542 | By similarity | |||||||||
| Disulfide bond | 4544 ↔ 4553 | By similarity | |||||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "A gene for a low density lipoprotein receptor-related protein in the nematode Caenorhabditis elegans." Yochem J., Greenwald I. Proc. Natl. Acad. Sci. U.S.A. 90:4572-4576(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. |
| [2] | "Genome sequence of the nematode C. elegans: a platform for investigating biology." The C. elegans sequencing consortium Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Bristol N2. |
| [3] | "Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins." Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J., Kasai K., Takahashi N., Isobe T. Nat. Biotechnol. 21:667-672(2003) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-118, MASS SPECTROMETRY. Strain: Bristol N2. |
| [4] | "Identification of the hydrophobic glycoproteins of Caenorhabditis elegans." Fan X., She Y.-M., Bagshaw R.D., Callahan J.W., Schachter H., Mahuran D.J. Glycobiology 15:952-964(2005) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1057; ASN-1597; ASN-1718 AND ASN-4248, MASS SPECTROMETRY. |
| [5] | "Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins." Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T. Mol. Cell. Proteomics 6:2100-2109(2007) [PubMed] [Europe PMC] [Abstract] Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-118; ASN-178; ASN-1431; ASN-1542; ASN-1545; ASN-1597; ASN-1718; ASN-2364; ASN-2762; ASN-3557; ASN-3752 AND ASN-4063, MASS SPECTROMETRY. Strain: Bristol N2. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | M96150 Genomic DNA. Translation: AAA28105.1. Z73907 Genomic DNA. Translation: CAA98124.1. |
| PIR | A47437. |
| RefSeq | NP_492127.1. NM_059726.5. |
3D structure databases | |
| ProteinModelPortal | Q04833. |
| SMR | Q04833. Positions 50-3225, 3235-4527. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 6239.F29D11.1. |
Proteomic databases | |
| PaxDb | Q04833. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblMetazoa | F29D11.1; F29D11.1; F29D11.1. |
| GeneID | 172520. |
| KEGG | cel:CELE_F29D11.1. |
| UCSC | F29D11.1. c. elegans. |
Organism-specific databases | |
| CTD | 172520. |
| WormBase | F29D11.1; CE05765; WBGene00003071; lrp-1. |
Phylogenomic databases | |
| eggNOG | NOG235850. |
| GeneTree | ENSGT00700000104037. |
| HOGENOM | HOG000230574. |
| InParanoid | Q04833. |
| KO | K06233. |
| OMA | TRPPGMC. |
Family and domain databases | |
| Gene3D | 2.120.10.30. 8 hits. 4.10.400.10. 35 hits. |
| InterPro | IPR011042. 6-blade_b-propeller_TolB-like. IPR000742. EG-like_dom. IPR001881. EGF-like_Ca-bd. IPR013032. EGF-like_CS. IPR018097. EGF_Ca-bd_CS. IPR009030. Growth_fac_rcpt. IPR023415. LDLR_class-A_CS. IPR000033. LDLR_classB_rpt. IPR002172. LDrepeatLR_classA_rpt. [Graphical view] |
| Pfam | PF00057. Ldl_recept_a. 29 hits. PF00058. Ldl_recept_b. 8 hits. [Graphical view] |
| SMART | SM00181. EGF. 13 hits. SM00179. EGF_CA. 2 hits. SM00192. LDLa. 35 hits. SM00135. LY. 32 hits. [Graphical view] |
| SUPFAM | SSF57184. Grow_fac_recept. 1 hit. SSF57424. LDL_rcpt_classA_cys-rich. 34 hits. |
| PROSITE | PS00010. ASX_HYDROXYL. 6 hits. PS00022. EGF_1. 1 hit. PS01186. EGF_2. 3 hits. PS50026. EGF_3. 2 hits. PS01187. EGF_CA. 3 hits. PS01209. LDLRA_1. 28 hits. PS50068. LDLRA_2. 34 hits. PS51120. LDLRB. 30 hits. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 875875. |
Entry information
| Entry name | LRP_CAEEL | ||||||||
| Accession | Primary (citable) accession number: Q04833 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Caenorhabditis annotation project | ||||||||
Relevant documents
| Caenorhabditis elegans Caenorhabditis elegans: entries, gene names and cross-references to WormBase |
| SIMILARITY comments Index of protein domains and families |