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Protein

Glutamine synthetase

Gene
N/A
Organism
Panulirus argus (Caribbean spiny lobster) (Palinurus argus)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Alternative name(s):
Glutamate--ammonia ligase
OrganismiPanulirus argus (Caribbean spiny lobster) (Palinurus argus)
Taxonomic identifieri6737 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaCrustaceaMalacostracaEumalacostracaEucaridaDecapodaPleocyemataAchelataPalinuroideaPalinuridaePanulirus

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Glutamine synthetasePRO_0000153145Add
BLAST

Interactioni

Subunit structurei

Homooctamer.

Structurei

3D structure databases

ProteinModelPortaliQ04831.
SMRiQ04831. Positions 6-360.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04831-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNQGANKTVL DRYLRLDIPD QKCQAMYIWV DGTGENLRSK TRTLNFTPKS
60 70 80 90 100
PSELPIWNFD GSSTGQAERS NSDVYLYPVA VYRDPFRLGN NKLVLCETYK
110 120 130 140 150
YNKKPADTNQ RWKCMEVMTR AADQHPWFGM EQEYTLLDID KHPLGWPKNG
160 170 180 190 200
YPGPQGPYYC GVGANRVYGR DVVEAHYRAC LCAGINISGE NAKVMPAQWE
210 220 230 240 250
FQVGPCEGIT MGDDLWMARY LLHRVAEDFD VVVTLDPKPI PGDWNGAGMH
260 270 280 290 300
TNFSTEAMRG PNGILEIESA IDKLSKVHEK HIKAYDPHAG KDNERRLTGH
310 320 330 340 350
YETSSIHDFS AGVANRGASI RIPRGVAEEK TGYLEDRRPS SNADPYVVSE
360
RLVRTICLNE Q
Length:361
Mass (Da):40,768
Last modified:October 1, 1993 - v1
Checksum:i3D8C3C507676099C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96798 mRNA. Translation: AAA02583.1.
PIRiJN0716.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M96798 mRNA. Translation: AAA02583.1.
PIRiJN0716.

3D structure databases

ProteinModelPortaliQ04831.
SMRiQ04831. Positions 6-360.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.30.590.10. 1 hit.
InterProiIPR008147. Gln_synt_beta.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
[Graphical view]
PfamiPF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
[Graphical view]
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiPS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "cDNA clones from the olfactory organ of the spiny lobster encode a protein related to eukaryotic glutamine synthetase."
    Trapido-Rosenthal H.G., Linser P.J., Greenberg R.M., Gleeson R.A., Carr W.E.
    Gene 129:275-278(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Tissue: Olfactory organ.

Entry informationi

Entry nameiGLNA_PANAR
AccessioniPrimary (citable) accession number: Q04831
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: October 1, 1993
Last modified: January 7, 2015
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.