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Protein

Uncharacterized protein YMR074C

Gene

YMR074C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Miscellaneous

Present with 2550 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

GO - Biological processi

  • hydrogen peroxide-mediated programmed cell death Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-32776-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YMR074C
Gene namesi
Ordered Locus Names:YMR074C
ORF Names:YM9916.13C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR074C
SGDiS000004678 YMR074C

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001215481 – 145Uncharacterized protein YMR074CAdd BLAST145

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1
Modified residuei121PhosphoserineCombined sources1
Modified residuei126PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ04773
PaxDbiQ04773
PRIDEiQ04773

PTM databases

iPTMnetiQ04773

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
URA3P039622EBI-28149,EBI-14397

Protein-protein interaction databases

BioGridi35249, 110 interactors
DIPiDIP-5242N
IntActiQ04773, 9 interactors
MINTiQ04773
STRINGi4932.YMR074C

Structurei

Secondary structure

1145
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi3 – 15Combined sources13
Helixi44 – 47Combined sources4
Helixi52 – 64Combined sources13
Helixi66 – 82Combined sources17
Helixi91 – 104Combined sources14

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2FH0NMR-A36-116[»]
2JXNNMR-A1-116[»]
ProteinModelPortaliQ04773
SMRiQ04773
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ04773

Family & Domainsi

Sequence similaritiesi

Belongs to the PDCD5 family.Curated

Phylogenomic databases

HOGENOMiHOG000194121
InParanoidiQ04773
KOiK06875
OMAiRLNTVKM
OrthoDBiEOG092C5N82

Family and domain databases

Gene3Di1.10.8.140, 1 hit
InterProiView protein in InterPro
IPR002836 PDCD5-like
IPR036883 PDCD5-like_sf
PANTHERiPTHR10840 PTHR10840, 1 hit
PfamiView protein in Pfam
PF01984 dsDNA_bind, 1 hit
PIRSFiPIRSF015730 TFAR19, 1 hit
SUPFAMiSSF46950 SSF46950, 1 hit

Sequencei

Sequence statusi: Complete.

Q04773-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPELQAIRE ARLAQLKNNS GGTNGDRNSG ANNGGGENSA PVGAAIANFL
60 70 80 90 100
EPQALERLSR VALVRRDRAQ AVETYLKKLI ATNNVTHKIT EAEIVSILNG
110 120 130 140
IAKQQNSQNN SKIIFERKDF SEDLNSFDKQ NAKNDDDEDD DDFFD
Length:145
Mass (Da):15,977
Last modified:November 1, 1997 - v1
Checksum:i36EEA1AFA3F6135D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48952 Genomic DNA Translation: CAA88799.1
BK006946 Genomic DNA Translation: DAA09972.1
PIRiS52834
RefSeqiNP_013790.1, NM_001182572.1

Genome annotation databases

EnsemblFungiiYMR074C; YMR074C; YMR074C
GeneIDi855096
KEGGisce:YMR074C

Similar proteinsi

Entry informationi

Entry nameiYMW4_YEAST
AccessioniPrimary (citable) accession number: Q04773
Secondary accession number(s): D6VZP8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
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Main funding by: National Institutes of Health