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Protein

Uncharacterized protein YMR074C

Gene

YMR074C

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • hydrogen peroxide-mediated programmed cell death Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-32776-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein YMR074C
Gene namesi
Ordered Locus Names:YMR074C
ORF Names:YM9916.13C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR074C.
SGDiS000004678. YMR074C.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 145145Uncharacterized protein YMR074CPRO_0000121548Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineCombined sources
Modified residuei121 – 1211PhosphoserineCombined sources
Modified residuei126 – 1261PhosphoserineCombined sources

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ04773.

PTM databases

iPTMnetiQ04773.

Interactioni

Protein-protein interaction databases

BioGridi35249. 37 interactions.
DIPiDIP-5242N.
MINTiMINT-536983.

Structurei

Secondary structure

1
145
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi3 – 1513Combined sources
Helixi44 – 474Combined sources
Helixi52 – 6413Combined sources
Helixi66 – 8217Combined sources
Helixi91 – 10414Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FH0NMR-A36-116[»]
2JXNNMR-A1-116[»]
ProteinModelPortaliQ04773.
SMRiQ04773. Positions 1-116.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ04773.

Family & Domainsi

Sequence similaritiesi

Belongs to the PDCD5 family.Curated

Phylogenomic databases

HOGENOMiHOG000194121.
InParanoidiQ04773.
KOiK06875.
OMAiQMETILL.
OrthoDBiEOG79KPTV.

Family and domain databases

Gene3Di1.10.8.140. 1 hit.
InterProiIPR002836. PDCD5-related.
[Graphical view]
PANTHERiPTHR10840. PTHR10840. 1 hit.
PfamiPF01984. dsDNA_bind. 1 hit.
[Graphical view]
PIRSFiPIRSF015730. TFAR19. 1 hit.
SUPFAMiSSF46950. SSF46950. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04773-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDPELQAIRE ARLAQLKNNS GGTNGDRNSG ANNGGGENSA PVGAAIANFL
60 70 80 90 100
EPQALERLSR VALVRRDRAQ AVETYLKKLI ATNNVTHKIT EAEIVSILNG
110 120 130 140
IAKQQNSQNN SKIIFERKDF SEDLNSFDKQ NAKNDDDEDD DDFFD
Length:145
Mass (Da):15,977
Last modified:November 1, 1997 - v1
Checksum:i36EEA1AFA3F6135D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48952 Genomic DNA. Translation: CAA88799.1.
BK006946 Genomic DNA. Translation: DAA09972.1.
PIRiS52834.
RefSeqiNP_013790.1. NM_001182572.1.

Genome annotation databases

EnsemblFungiiYMR074C; YMR074C; YMR074C.
GeneIDi855096.
KEGGisce:YMR074C.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48952 Genomic DNA. Translation: CAA88799.1.
BK006946 Genomic DNA. Translation: DAA09972.1.
PIRiS52834.
RefSeqiNP_013790.1. NM_001182572.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2FH0NMR-A36-116[»]
2JXNNMR-A1-116[»]
ProteinModelPortaliQ04773.
SMRiQ04773. Positions 1-116.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi35249. 37 interactions.
DIPiDIP-5242N.
MINTiMINT-536983.

PTM databases

iPTMnetiQ04773.

Proteomic databases

MaxQBiQ04773.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYMR074C; YMR074C; YMR074C.
GeneIDi855096.
KEGGisce:YMR074C.

Organism-specific databases

EuPathDBiFungiDB:YMR074C.
SGDiS000004678. YMR074C.

Phylogenomic databases

HOGENOMiHOG000194121.
InParanoidiQ04773.
KOiK06875.
OMAiQMETILL.
OrthoDBiEOG79KPTV.

Enzyme and pathway databases

BioCyciYEAST:G3O-32776-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ04773.
PROiQ04773.

Family and domain databases

Gene3Di1.10.8.140. 1 hit.
InterProiIPR002836. PDCD5-related.
[Graphical view]
PANTHERiPTHR10840. PTHR10840. 1 hit.
PfamiPF01984. dsDNA_bind. 1 hit.
[Graphical view]
PIRSFiPIRSF015730. TFAR19. 1 hit.
SUPFAMiSSF46950. SSF46950. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
  4. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121 AND SER-126, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution."
    Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.
    Science 325:1682-1686(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiYMW4_YEAST
AccessioniPrimary (citable) accession number: Q04773
Secondary accession number(s): D6VZP8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 6, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 2550 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families
  3. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  4. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.