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Protein

Golgi apparatus membrane protein TVP18

Gene

TVP18

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Golgi membrane protein involved in vesicular trafficking.1 Publication

GO - Biological processi

  • vesicle-mediated transport Source: SGD

Enzyme and pathway databases

BioCyciYEAST:G3O-32773-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Golgi apparatus membrane protein TVP18
Alternative name(s):
TLG2 compartment vesicle protein of 18 kDa
Gene namesi
Name:TVP18
Ordered Locus Names:YMR071C
ORF Names:YM9916.10C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR071C
SGDiS000004675 TVP18

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei23 – 43HelicalSequence analysisAdd BLAST21
Transmembranei49 – 69HelicalSequence analysisAdd BLAST21
Transmembranei98 – 114HelicalSequence analysisAdd BLAST17
Transmembranei121 – 137HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002032811 – 167Golgi apparatus membrane protein TVP18Add BLAST167

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi22N-linked (GlcNAc...) asparagineSequence analysis1
Modified residuei146PhosphothreonineCombined sources1
Modified residuei153PhosphothreonineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

MaxQBiQ04767
PaxDbiQ04767
PRIDEiQ04767

PTM databases

iPTMnetiQ04767
SwissPalmiQ04767

Interactioni

Subunit structurei

Interacts with TVP15 and YIP4.1 Publication

Protein-protein interaction databases

BioGridi35246, 75 interactors
DIPiDIP-1731N
IntActiQ04767, 14 interactors
MINTiQ04767
STRINGi4932.YMR071C

Structurei

3D structure databases

ProteinModelPortaliQ04767
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TVP18 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000066042
InParanoidiQ04767
OMAiFSIYGQW
OrthoDBiEOG092C5B1P

Family and domain databases

InterProiView protein in InterPro
IPR019365 TVP18/Ca-channel_flower
PANTHERiPTHR13314 PTHR13314, 1 hit
PfamiView protein in Pfam
PF10233 Cg6151-P, 1 hit
SMARTiView protein in SMART
SM01077 Cg6151-P, 1 hit

Sequencei

Sequence statusi: Complete.

Q04767-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALSLGQFIN VGGMVKDLKS FNFSVYGRWF GYINIILCIA LGIANLFHVS
60 70 80 90 100
GVIAFGIISI IQGLVILFIE IPFLLKICPL SDNFIEFIKR FETNGWRCLF
110 120 130 140 150
YLAMAIIQYI SIAVMATSLI VVAVGLTISS ISYAVAYTKH QEFQNTNIIK
160
NPTDDDFPHE AVVREML
Length:167
Mass (Da):18,693
Last modified:November 1, 1997 - v1
Checksum:i46698DC0400D3097
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48952 Genomic DNA Translation: CAA88796.1
AY558402 Genomic DNA Translation: AAS56728.1
BK006946 Genomic DNA Translation: DAA09969.1
PIRiS52831
RefSeqiNP_013787.1, NM_001182569.1

Genome annotation databases

EnsemblFungiiYMR071C; YMR071C; YMR071C
GeneIDi855093
KEGGisce:YMR071C

Similar proteinsi

Entry informationi

Entry nameiTVP18_YEAST
AccessioniPrimary (citable) accession number: Q04767
Secondary accession number(s): D6VZP5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 23, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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