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Protein

Protein RecA

Gene

recA

Organism
Brucella abortus biovar 1 (strain 9-941)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.UniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi77 – 848ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

DNA damage, DNA recombination, DNA repair, SOS response

Keywords - Ligandi

ATP-binding, DNA-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBABO262698:GJC2-1229-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein RecAUniRule annotation
Alternative name(s):
Recombinase AUniRule annotation
Gene namesi
Name:recAUniRule annotation
Ordered Locus Names:BruAb1_1207
OrganismiBrucella abortus biovar 1 (strain 9-941)
Taxonomic identifieri262698 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBrucellaceaeBrucella
ProteomesiUP000000540 Componenti: Chromosome I

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Protein RecAPRO_0000122670Add
BLAST

Proteomic databases

PRIDEiQ04761.

Structurei

3D structure databases

ProteinModelPortaliQ04761.
SMRiQ04761. Positions 15-336.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RecA family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0468.
HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.
OrthoDBiEOG6ZKXNZ.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04761-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQNSLRLVE DNSVDKTKAL DAALSQIERA FGKGSIMRLG QNDQVVEIET
60 70 80 90 100
VSTGSLSLDI ALGVGGLPKG RIVEIYGPES SGKTTLALHT IAEAQKKGGI
110 120 130 140 150
CAFVDAEHAL DPVYARKLGV DLENLLISQP DTGEQALEIT DTLVRSGAID
160 170 180 190 200
VLVVDSVAAL TPRAEIEGEM GDSLPGLQAR LMSQALRKLT GSISRSNCMV
210 220 230 240 250
IFINQIRMKI GVMFGSPETT TGGNALKFYA SVRLDIRRIG SIKERDEVVG
260 270 280 290 300
NQTRVKVVKN KLAPPFKQVE FDIMYGAGVS KVGELVDLGV KAGVVEKSGA
310 320 330 340 350
WFSYNSQRLG QGRENAKQYL KDNPEVAREI ETTLRQNAGL IAEQFLDDGG
360
PEEDAAGAAE M
Length:361
Mass (Da):38,735
Last modified:June 21, 2005 - v2
Checksum:i6E15766D33E5756E
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti121 – 1211D → H in AAA22999 (PubMed:8321120).Curated
Sequence conflicti131 – 1311D → I in AAA22999 (PubMed:8321120).Curated
Sequence conflicti174 – 1752LP → H in AAA22999 (PubMed:8321120).Curated
Sequence conflicti186 – 1861L → V in AAA22999 (PubMed:8321120).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L00679 Genomic DNA. Translation: AAA22999.1.
AE017223 Genomic DNA. Translation: AAX74545.1.
PIRiI40347.
RefSeqiWP_002964332.1. NC_006932.1.

Genome annotation databases

EnsemblBacteriaiAAX74545; AAX74545; BruAb1_1207.
GeneIDi3788897.
KEGGibmb:BruAb1_1207.
PATRICi17824104. VBIBruAbo15061_1274.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L00679 Genomic DNA. Translation: AAA22999.1.
AE017223 Genomic DNA. Translation: AAX74545.1.
PIRiI40347.
RefSeqiWP_002964332.1. NC_006932.1.

3D structure databases

ProteinModelPortaliQ04761.
SMRiQ04761. Positions 15-336.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ04761.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAX74545; AAX74545; BruAb1_1207.
GeneIDi3788897.
KEGGibmb:BruAb1_1207.
PATRICi17824104. VBIBruAbo15061_1274.

Phylogenomic databases

eggNOGiCOG0468.
HOGENOMiHOG000264120.
KOiK03553.
OMAiTRKGAWY.
OrthoDBiEOG6ZKXNZ.

Enzyme and pathway databases

BioCyciBABO262698:GJC2-1229-MONOMER.

Miscellaneous databases

PROiQ04761.

Family and domain databases

Gene3Di3.30.250.10. 1 hit.
3.40.50.300. 1 hit.
HAMAPiMF_00268. RecA.
InterProiIPR003593. AAA+_ATPase.
IPR013765. DNA_recomb/repair_RecA.
IPR020584. DNA_recomb/repair_RecA_CS.
IPR027417. P-loop_NTPase.
IPR020588. RecA_ATP-bd.
IPR023400. RecA_C.
IPR020587. RecA_monomer-monomer_interface.
[Graphical view]
PANTHERiPTHR22942:SF1. PTHR22942:SF1. 1 hit.
PfamiPF00154. RecA. 1 hit.
[Graphical view]
PRINTSiPR00142. RECA.
SMARTiSM00382. AAA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF54752. SSF54752. 1 hit.
TIGRFAMsiTIGR02012. tigrfam_recA. 1 hit.
PROSITEiPS00321. RECA_1. 1 hit.
PS50162. RECA_2. 1 hit.
PS50163. RECA_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Construction of a Brucella abortus RecA mutant and its survival in mice."
    Tatum F.M.
    Microb. Pathog. 14:177-185(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "Completion of the genome sequence of Brucella abortus and comparison to the highly similar genomes of Brucella melitensis and Brucella suis."
    Halling S.M., Peterson-Burch B.D., Bricker B.J., Zuerner R.L., Qing Z., Li L.-L., Kapur V., Alt D.P., Olsen S.C.
    J. Bacteriol. 187:2715-2726(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 9-941.

Entry informationi

Entry nameiRECA_BRUAB
AccessioniPrimary (citable) accession number: Q04761
Secondary accession number(s): Q57CT9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1993
Last sequence update: June 21, 2005
Last modified: July 22, 2015
This is version 106 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Brucella abortus strain 9-941
    Brucella abortus (strain 9-941): entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.