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Protein

Body wall muscle protein HR-29

Gene
N/A
Organism
Halocynthia roretzi (Sea squirt) (Cynthia roretzi)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May be a component of myofibrils where it acts as a stabilizer.

Keywords - Molecular functioni

Muscle protein

Names & Taxonomyi

Protein namesi
Recommended name:
Body wall muscle protein HR-29
OrganismiHalocynthia roretzi (Sea squirt) (Cynthia roretzi)
Taxonomic identifieri7729 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataTunicataAscidiaceaStolidobranchiaPyuridaeHalocynthia

Subcellular locationi

  • Membrane 1 Publication; Peripheral membrane protein 1 Publication

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved1 Publication
Chaini2 – 252251Body wall muscle protein HR-29PRO_0000126061Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserine1 Publication

Keywords - PTMi

Acetylation

Interactioni

Subunit structurei

Exists as an oligomer.1 Publication

Structurei

3D structure databases

ProteinModelPortaliQ04757.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Repeati37 – 55191Add
BLAST
Repeati56 – 74192Add
BLAST
Repeati75 – 93193Add
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni37 – 93573 X 19 AA approximate tandem repeatsAdd
BLAST

Sequence similaritiesi

Belongs to the small heat shock protein (HSP20) family.PROSITE-ProRule annotation

Keywords - Domaini

Repeat

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q04757-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLMPFDDFY YPYQLRRRSP RWMDSTGSPW DSFATSRDWM TTPYSSTGIG
60 70 80 90 100
RRDLSQDWMT TPYTPAGVGR RDLSQDWMTT PYTSKGIGSR NLSSWGSKSE
110 120 130 140 150
TIREMEKKFD ELVRKVDRRF TGMLSMLDDP EPFARQNISV EHEGKTTSKT
160 170 180 190 200
TKLQDFNMKV DVQDFKPEEV KVKVQGGQVL VHAKRENRDE GDGMFAYSCS
210 220 230 240 250
EFKRAFILPE GVSAERLTSS LSRDGILQID APVAVAIDNK KTAVPVTVEH

TK
Length:252
Mass (Da):28,763
Last modified:January 23, 2007 - v2
Checksum:iF177CB18D868C390
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13917 mRNA. Translation: BAA03012.1.
D13918 Genomic DNA. Translation: BAA03013.1.
S60426 Genomic DNA. Translation: AAA15484.2.
PIRiJX0258.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D13917 mRNA. Translation: BAA03012.1.
D13918 Genomic DNA. Translation: BAA03013.1.
S60426 Genomic DNA. Translation: AAA15484.2.
PIRiJX0258.

3D structure databases

ProteinModelPortaliQ04757.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di2.60.40.790. 1 hit.
InterProiIPR002068. A-crystallin/Hsp20_dom.
IPR001436. Alpha-crystallin/HSP.
IPR031107. HSP20.
IPR008978. HSP20-like_chaperone.
[Graphical view]
PANTHERiPTHR11527. PTHR11527. 1 hit.
PfamiPF00011. HSP20. 1 hit.
[Graphical view]
PRINTSiPR00299. ACRYSTALLIN.
SUPFAMiSSF49764. SSF49764. 1 hit.
PROSITEiPS01031. HSP20. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Structure of 29-kDa protein from ascidian (Halocynthia roretzi) body wall muscle."
    Takagi T., Yasunaga H., Nakamura A.
    J. Biochem. 113:321-326(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA], PROTEIN SEQUENCE OF 2-252.
    Tissue: Body wall muscle.
  2. "Isolation and characterization of a 29,000 Dalton protein from ascidian (Halocynthia roretzi) body wall muscle."
    Shirakata M., Takagi T., Konishi K.
    Comp. Biochem. Physiol. 85B:71-76(1986)
    Cited for: SUBUNIT, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiHR29_HALRO
AccessioniPrimary (citable) accession number: Q04757
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 7, 2004
Last sequence update: January 23, 2007
Last modified: June 24, 2015
This is version 61 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.