Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q04751

- NAT4_YEAST

UniProt

Q04751 - NAT4_YEAST

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Histone-specific N-acetyltransferase NAT4

Gene

NAT4

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Responsible for the acetylation of the N-terminal residues of histones H4 and H2A.1 Publication

GO - Molecular functioni

  1. histone acetyltransferase activity Source: SGD

GO - Biological processi

  1. histone acetylation Source: SGD
  2. regulation of chromatin silencing at rDNA Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Acyltransferase, Transferase

Enzyme and pathway databases

BioCyciYEAST:G3O-32771-MONOMER.
BRENDAi2.3.1.48. 984.

Names & Taxonomyi

Protein namesi
Recommended name:
Histone-specific N-acetyltransferase NAT4 (EC:2.3.1.-)
Gene namesi
Name:NAT4
Ordered Locus Names:YMR069W
ORF Names:YM9916.08
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311: Chromosome XIII

Organism-specific databases

CYGDiYMR069w.
SGDiS000004673. NAT4.

Subcellular locationi

Nucleus 1 Publication. Cytoplasm 1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
  2. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 285285Histone-specific N-acetyltransferase NAT4PRO_0000074636Add
BLAST

Proteomic databases

PaxDbiQ04751.

Expressioni

Gene expression databases

GenevestigatoriQ04751.

Interactioni

Protein-protein interaction databases

BioGridi35244. 41 interactions.
DIPiDIP-2745N.
IntActiQ04751. 2 interactions.
MINTiMINT-575427.
STRINGi4932.YMR069W.

Structurei

3D structure databases

ProteinModelPortaliQ04751.
SMRiQ04751. Positions 138-252.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini88 – 274187N-acetyltransferasePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 N-acetyltransferase domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiCOG0454.
InParanoidiQ04751.
OrthoDBiEOG7DNP74.

Family and domain databases

Gene3Di3.40.630.30. 1 hit.
InterProiIPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view]
PfamiPF00583. Acetyltransf_1. 1 hit.
[Graphical view]
SUPFAMiSSF55729. SSF55729. 1 hit.
PROSITEiPS51186. GNAT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04751-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MRSSVYSENT YNCIRTSKEH LTERRRVAMA PMFQHFLNLC VEKFPESIEH
60 70 80 90 100
KDTDGNGNFT TAILEREIIY IPEDDTDSID SVDSLKCINY KLHKSRGDQV
110 120 130 140 150
LDACVQLIDK HLGAKYRRAS RIMYGNRKPW KANKLAEMKS AGLVYVCYWD
160 170 180 190 200
NGVLGAFTSF MLTEETGLVE GDALHEVSVP VIYLYEVHVA SAHRGHGIGR
210 220 230 240 250
RLLEHALCDG VARHTRRMCD NFFGVALTVF SDNTRARRLY EALGFYRAPG
260 270 280
SPAPASPTIR HTRHGGGRVV VPCDPLYYVY CLHMP
Length:285
Mass (Da):32,334
Last modified:November 1, 1997 - v1
Checksum:i20127B782E1F5F1A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48952 Genomic DNA. Translation: CAA88794.1.
AY557984 Genomic DNA. Translation: AAS56310.1.
BK006946 Genomic DNA. Translation: DAA09967.1.
PIRiS52829.
RefSeqiNP_013785.1. NM_001182567.1.

Genome annotation databases

EnsemblFungiiYMR069W; YMR069W; YMR069W.
GeneIDi855091.
KEGGisce:YMR069W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48952 Genomic DNA. Translation: CAA88794.1 .
AY557984 Genomic DNA. Translation: AAS56310.1 .
BK006946 Genomic DNA. Translation: DAA09967.1 .
PIRi S52829.
RefSeqi NP_013785.1. NM_001182567.1.

3D structure databases

ProteinModelPortali Q04751.
SMRi Q04751. Positions 138-252.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 35244. 41 interactions.
DIPi DIP-2745N.
IntActi Q04751. 2 interactions.
MINTi MINT-575427.
STRINGi 4932.YMR069W.

Proteomic databases

PaxDbi Q04751.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblFungii YMR069W ; YMR069W ; YMR069W .
GeneIDi 855091.
KEGGi sce:YMR069W.

Organism-specific databases

CYGDi YMR069w.
SGDi S000004673. NAT4.

Phylogenomic databases

eggNOGi COG0454.
InParanoidi Q04751.
OrthoDBi EOG7DNP74.

Enzyme and pathway databases

BioCyci YEAST:G3O-32771-MONOMER.
BRENDAi 2.3.1.48. 984.

Miscellaneous databases

NextBioi 978396.

Gene expression databases

Genevestigatori Q04751.

Family and domain databases

Gene3Di 3.40.630.30. 1 hit.
InterProi IPR016181. Acyl_CoA_acyltransferase.
IPR000182. GNAT_dom.
[Graphical view ]
Pfami PF00583. Acetyltransf_1. 1 hit.
[Graphical view ]
SUPFAMi SSF55729. SSF55729. 1 hit.
PROSITEi PS51186. GNAT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  4. "An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A."
    Song O.-K., Wang X., Waterborg J.H., Sternglanz R.
    J. Biol. Chem. 278:38109-38112(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
  5. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  6. "A multidimensional chromatography technology for in-depth phosphoproteome analysis."
    Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
    Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiNAT4_YEAST
AccessioniPrimary (citable) accession number: Q04751
Secondary accession number(s): D6VZP3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: October 29, 2014
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XIII
    Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

External Data

Dasty 3