Q04734 (PALI_YEAST) Reviewed, UniProtKB/Swiss-Prot
Last modified
December 14, 2011.
Version 77.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: pH-response regulator protein palI/RIM9 Alternative name(s): Regulator of IME2 protein 9 | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | ||||||
| Taxonomic identifier | 559292 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 239 AA. |
| Sequence status | Complete. |
| Protein existence | Evidence at protein level |
General annotation (Comments)
| Function | Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. Ref.1 |
| Subcellular location | Cell membrane; Multi-pass membrane protein Potential. |
| Sequence similarities | Belongs to the palI/RIM9 family. |
Ontologies
| Keywords | |
|---|---|
| Cellular component | Cell membrane Membrane |
| Domain | Transmembrane Transmembrane helix |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | ascospore formation Inferred from mutant phenotype. Source: SGD |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 239 | 239 | pH-response regulator protein palI/RIM9 | PRO_0000058216 | |||||
Regions | |||||||||
| Topological domain | 1 – 3 | 3 | Cytoplasmic Potential | ||||||
| Transmembrane | 4 – 24 | 21 | Helical; Potential | ||||||
| Topological domain | 25 – 90 | 66 | Extracellular Potential | ||||||
| Transmembrane | 91 – 111 | 21 | Helical; Potential | ||||||
| Topological domain | 112 – 128 | 17 | Cytoplasmic Potential | ||||||
| Transmembrane | 129 – 149 | 21 | Helical; Potential | ||||||
| Topological domain | 150 – 155 | 6 | Extracellular Potential | ||||||
| Transmembrane | 156 – 176 | 21 | Helical; Potential | ||||||
| Topological domain | 177 – 239 | 63 | Cytoplasmic Potential | ||||||
Sequences
| ||||||||||||||||||
References
| « Hide 'large scale' references | |
| [1] | "Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth." Li W., Mitchell A.P. Genetics 145:63-73(1997) [PubMed: 9017390] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION. |
| [2] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G.Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [3] | Saccharomyces Genome Database Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases Cited for: GENOME REANNOTATION. Strain: ATCC 204508 / S288c. |
| [4] | "Characterization of a second nuclear gene, AEP1, required for expression of the mitochondrial OLI1 gene in Saccharomyces cerevisiae." Payne M.J., Lukins H.B. Curr. Genet. 24:126-135(1993) [PubMed: 8358819] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 70-239. |
| [5] | "A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS]. Strain: ATCC 208353 / W303-1A. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | U86641 Genomic DNA. Translation: AAC49630.1. Z48952 Genomic DNA. Translation: CAA88788.1. M80615 Unassigned DNA. No translation available. BK006946 Genomic DNA. Translation: DAA09961.1. |
| PIR | S52823. |
| RefSeq | NP_013779.1. NM_001182561.1. |
3D structure databases | |
| ProteinModelPortal | Q04734. |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP-4447N. |
| IntAct | Q04734. 1 interaction. |
| MINT | MINT-496242. |
| STRING | Q04734. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | YMR063W; YMR063W; YMR063W. |
| GeneID | 855085. |
| KEGG | sce:YMR063W. |
| NMPDR | fig|4932.3.peg.4826. |
Organism-specific databases | |
| CYGD | YMR063w. |
| SGD | S000004667. RIM9. |
Phylogenomic databases | |
| eggNOG | fuNOG12773. |
| GeneTree | EFGT00050000000903. |
| OMA | DWPGWLM. |
| OrthoDB | EOG4DBXQ8. |
Gene expression databases | |
| ArrayExpress | Q04734. |
| Genevestigator | Q04734. |
| GermOnline | YMR063W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR009571. SUR7/PalI. [Graphical view] |
| Pfam | PF06687. SUR7. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 978378. |
Entry information
| Entry name | PALI_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q04734 Secondary accession number(s): D6VZN7 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome XIII Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names |
| SIMILARITY comments Index of protein domains and families |

Clusters with