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Q04734 (PALI_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
pH-response regulator protein palI/RIM9
Alternative name(s):
Regulator of IME2 protein 9
Gene names
Name:RIM9
Ordered Locus Names:YMR063W
ORF Names:YM9916.02
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length239 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for the proteolytic cleavage of the transcriptional repressor RIM101 in response to alkaline ambient pH, which is necessary for sporulation and invasive growth. Ref.1

Subcellular location

Cell membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the palI/RIM9 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 239239pH-response regulator protein palI/RIM9
PRO_0000058216

Regions

Topological domain1 – 33Cytoplasmic Potential
Transmembrane4 – 2421Helical; Potential
Topological domain25 – 9066Extracellular Potential
Transmembrane91 – 11121Helical; Potential
Topological domain112 – 12817Cytoplasmic Potential
Transmembrane129 – 14921Helical; Potential
Topological domain150 – 1556Extracellular Potential
Transmembrane156 – 17621Helical; Potential
Topological domain177 – 23963Cytoplasmic Potential

Sequences

Sequence LengthMass (Da)Tools
Q04734 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 8310BF42D5A27E10

FASTA23926,697
        10         20         30         40         50         60 
MVSMIHIVVF LLAITTMFEI LPLITVPVTK YLSLSSFRNH YYGLFGWCVR GQNQELMCTK 

        70         80         90        100        110        120 
MKIGYDSTDV DSSGHVLTLP SNSKVVVSNL LVVHPISLAF TGTLLILAVI IMVTPLGDSP 

       130        140        150        160        170        180 
EMLLFTALFS LPTFMLCLLC FLVDILLFIS KLDWPGWLML AATISVALCC SMLWVMRRVV 

       190        200        210        220        230 
SVKKYESQQS IAHACSMEQY SISDIYQSKQ NGNSSEYEVA PTHTDSLIAP EVTYRGFIE 

« Hide

References

« Hide 'large scale' references
[1]"Proteolytic activation of Rim1p, a positive regulator of yeast sporulation and invasive growth."
Li W., Mitchell A.P.
Genetics 145:63-73(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION.
[2]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"Characterization of a second nuclear gene, AEP1, required for expression of the mitochondrial OLI1 gene in Saccharomyces cerevisiae."
Payne M.J., Lukins H.B.
Curr. Genet. 24:126-135(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 70-239.
[5]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U86641 Genomic DNA. Translation: AAC49630.1.
Z48952 Genomic DNA. Translation: CAA88788.1.
M80615 Unassigned DNA. No translation available.
BK006946 Genomic DNA. Translation: DAA09961.1.
PIRS52823.
RefSeqNP_013779.1. NM_001182561.1.

3D structure databases

ProteinModelPortalQ04734.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid35238. 123 interactions.
DIPDIP-4447N.
IntActQ04734. 1 interaction.
MINTMINT-496242.
STRING4932.YMR063W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYMR063W; YMR063W; YMR063W.
GeneID855085.
KEGGsce:YMR063W.

Organism-specific databases

CYGDYMR063w.
SGDS000004667. RIM9.

Phylogenomic databases

eggNOGNOG12793.
HOGENOMHOG000115433.
OMADWPGWLM.
OrthoDBEOG7QVMDM.

Enzyme and pathway databases

BioCycYEAST:G3O-32765-MONOMER.

Gene expression databases

GenevestigatorQ04734.

Family and domain databases

InterProIPR009571. SUR7/PalI.
[Graphical view]
PfamPF06687. SUR7. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio978378.

Entry information

Entry namePALI_YEAST
AccessionPrimary (citable) accession number: Q04734
Secondary accession number(s): D6VZN7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: February 19, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families