Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

54S ribosomal protein L34, mitochondrial

Gene

YDR115W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Component of the mitochondrial ribosome (mitoribosome), a dedicated translation machinery responsible for the synthesis of mitochondrial genome-encoded proteins, including at least some of the essential transmembrane subunits of the mitochondrial respiratory chain. The mitoribosomes are attached to the mitochondrial inner membrane and translation products are cotranslationally integrated into the membrane.2 Publications

Miscellaneous

Present with 200 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

BioCyciYEAST:G3O-29715-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
54S ribosomal protein L34, mitochondrial
Short name:
L34mt
Alternative name(s):
Mitochondrial large ribosomal subunit protein bL34m1 Publication
Gene namesi
Ordered Locus Names:YDR115W
ORF Names:YD9727.10
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR115W.
SGDiS000002522. YDR115W.

Subcellular locationi

  • Mitochondrion 1 Publication

  • Note: Mitoribosomes are tethered to the mitochondrial inner membrane and spatially aligned with the membrane insertion machinery through two distinct membrane contact sites, formed by the 21S rRNA expansion segment 96-ES1 and the inner membrane protein MBA1.1 Publication

GO - Cellular componenti

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 16MitochondrionSequence analysisAdd BLAST16
ChainiPRO_000003052317 – 10554S ribosomal protein L34, mitochondrialAdd BLAST89

Interactioni

Subunit structurei

Component of the mitochondrial large ribosomal subunit (mt-LSU). Mature yeast 74S mitochondrial ribosomes consist of a small (37S) and a large (54S) subunit. The 37S small subunit contains a 15S ribosomal RNA (15S mt-rRNA) and 34 different proteins. The 54S large subunit contains a 21S rRNA (21S mt-rRNA) and 46 different proteins.1 Publication

Protein-protein interaction databases

BioGridi32171. 139 interactors.
DIPiDIP-1824N.
IntActiQ04598. 2 interactors.
MINTiMINT-386975.
STRINGi4932.YDR115W.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
3J6Belectron microscopy3.20Y1-105[»]
5MRCelectron microscopy3.25Y60-105[»]
5MREelectron microscopy3.75Y60-105[»]
5MRFelectron microscopy4.97Y60-105[»]
ProteinModelPortaliQ04598.
SMRiQ04598.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

InParanoidiQ04598.
KOiK02914.
OrthoDBiEOG092C5KYC.

Family and domain databases

HAMAPiMF_00391. Ribosomal_L34. 1 hit.
InterProiView protein in InterPro
IPR000271. Ribosomal_L34.
PANTHERiPTHR14503. PTHR14503. 1 hit.
PfamiView protein in Pfam
PF00468. Ribosomal_L34. 1 hit.
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003101. Ribosomal_L34. 1 hit.
TIGRFAMsiTIGR01030. rpmH_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q04598-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLFARLCQP QSRRMFSSIS SFSALSVLRP QTGMLLNSSP LKTPSFTPLG
60 70 80 90 100
FGLIGQRRWK SRGNTYQPST LKRKRTFGFL ARAKSKQGSK ILKRRKLKGR

WFLSH
Length:105
Mass (Da):12,030
Last modified:November 1, 1996 - v1
Checksum:i7A1C10A502C97EC5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z48758 Genomic DNA. Translation: CAA88668.1.
AY557661 Genomic DNA. Translation: AAS55987.1.
BK006938 Genomic DNA. Translation: DAA11960.1.
PIRiS52680.
RefSeqiNP_010400.1. NM_001180423.1.

Genome annotation databases

EnsemblFungiiYDR115W; YDR115W; YDR115W.
GeneIDi851692.
KEGGisce:YDR115W.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiRM34_YEAST
AccessioniPrimary (citable) accession number: Q04598
Secondary accession number(s): D6VSA0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 31, 2002
Last sequence update: November 1, 1996
Last modified: July 5, 2017
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names