Reviewed, UniProtKB/Swiss-Prot Q04564 (TR2M_AGRVI)

Names and origin

Protein names

Recommended name:
    Tryptophan 2-monooxygenase
    EC=1.13.12.3

Gene names

Name:

iaaM

Encoded on

Plasmid pTiS4

Organism

Agrobacterium vitis (Rhizobium vitis)

Taxonomic identifier

373 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Rhizobiaceae › Rhizobium/Agrobacterium group › Agrobacterium

Protein attributes

Sequence length	723 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-tryptophan + O(2) = (indol-3-yl)acetamide + CO(2) + H(2)O.
Pathway	Plant hormone metabolism; auxin biosynthesis.
Sequence similarities	Belongs to the tryptophan 2-monooxygenase family.

Ontologies

Keywords
Biological process	Auxin biosynthesis
Disease	Crown gall tumor
Molecular function	Monooxygenase Oxidoreductase
Technical term	Plasmid
Gene Ontology (GO)
Biological process	auxin biosynthetic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	electron carrier activity Inferred from electronic annotation. Source: InterPro nucleic acid binding Inferred from electronic annotation. Source: InterPro tryptophan 2-monooxygenase activity Inferred from electronic annotation. Source: InterPro zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 723	723	Tryptophan 2-monooxygenase		PRO_0000065588

Sequences

	Sequence		Length	Mass (Da)
	Q04564-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: ABA9CEA94B6B4E36	FASTA	723	80,803
	10 20 30 40 50 60 MANFFYSRIT NRSYSTKNLL NIEDKGRLKD ELEKTRQTNI CEICLHPRGH RASVCRQILM 70 80 90 100 110 120 GFAYTSKTVL EGLLSTMPHD DAPLGKIFVT DLPPYDEQVP QVLLMQAAAL VTSYEYSFED 130 140 150 160 170 180 LAYFLVLPLQ MALMQKSPSL GKDFPVISGY SITKDSVHSP VAFGRNLMPR GVSCEFPQID 190 200 210 220 230 240 VLYDYRGFLE GGAFSEGVTS FPKETKKPKV AVIGAGISGL VSATLLLRNG IDDVTIFEAK 250 260 270 280 290 300 NVVGGRAHTH FFKGEPSVCA ELGAMRFPRS QACLFYLLEY LGINAMTKFP NPGTVDTGLY 310 320 330 340 350 360 YRGRSYNWKA HSLPPAIFNR VHKGWRTFLH AGFVDGVAAF ASPFTLTECL RLRNYEFASS 370 380 390 400 410 420 LWQKWLDAFS SETFSSGIER IFRGAHPPGG EKWTRDVDME LFKELGVGSG GFGPVFGCGF 430 440 450 460 470 480 IEILRLIVNG YEDNVMLLLD GIEEIPRRLS QQKVGSYSIR DRIIHKEVKE IIRTESGISL 490 500 510 520 530 540 AIGEGMHATF DRVIVTSGFT NIQLRHLLTN DDSFFSYDVN QAIENSHMTG SSKLFVLTQN 550 560 570 580 590 600 KFWKAEELPS CILTTGVAKA VYCLDYEPDK PSGKGLVLLS YTWEDDSHKL LTFDKGERFQ 610 620 630 640 650 660 ILKRDLAKSY PRFADLLEPA DGDYDNNIIQ HDWILDPYAG GAFKLNRRCE DVYSKRLFFQ 670 680 690 700 710 720 PLRLNGEPDG RVCLAGCSCS FSGGWVEGAI QTACNAAMAT IRDAGGLISG DNPLTNEFVN YHY

References

[1]	"Organization and functional analysis of three T-DNAs from the vitopine Ti plasmid pTiS4." Canaday J., Gerard J.-C., Crouzet P., Otten L. Mol. Gen. Genet. 235:292-303(1992) [PubMed: 1465104] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: S4.

Cross-references

Sequence databases
EMBLGenBankDDBJ	M91609 Genomic DNA. Translation: AAA98149.1.
PIR	S30105.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR000759. Adrndx_reductase. IPR002937. Amino_oxidase. IPR006064. Glycosidase. IPR001452. SH3. IPR012142. Trp_2-mOase. IPR001878. Znf_CCHC. [Graphical view]
Pfam	PF01593. Amino_oxidase. 1 hit. PF02027. RolB_RolC. 1 hit. [Graphical view]
PIRSF	PIRSF000319. Trp_2-mono_O2ase. 1 hit.
PRINTS	PR00419. ADXRDTASE. PR00452. SH3DOMAIN.
SMART	SM00343. ZnF_C2HC. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TR2M_AGRVI

Accession

Primary (citable) accession number: Q04564

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	November 25, 2008
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)