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Q04550 (VP2_SOUV3) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene names
ORF Names:ORF3
OrganismSouthampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK) [Complete proteome]
Taxonomic identifier37129 [NCBI]
Taxonomic lineageVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus
Virus hostHomo sapiens (Human) [TaxID: 9606]

Protein attributes

Sequence length211 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Minor structural protein present in one or two copies per virion. Stabilizes capsid protein VP1 by protecting it from disassembly and degradation. May play a role in RNA genome packaging By similarity.

Subcellular location

Virion. Host cytoplasm By similarity.

Miscellaneous

Translated by a ribosomal termination-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Sequence similarities

Belongs to the norovirus VP2 family.

Ontologies

Keywords
   Cellular componentHost cytoplasm
Virion
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componenthost cell cytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

virion

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 211211Protein VP2
PRO_0000100131

Sequences

Sequence LengthMass (Da)Tools
Q04550 [UniParc].

Last modified October 1, 1994. Version 1.
Checksum: 3D6D1B51CC3C27B4

FASTA21122,257
        10         20         30         40         50         60 
MAQAIIGAIA ASAAGSALGA GIQAGAEAAL QSQRYQQDLA LQRNTFEHDK DMLSYQVQAS 

        70         80         90        100        110        120 
NALLAKNLNT RYSMLIAGGL SSADASRAVA GAPVTRLIDW NGTRVAAPRS SATTLRSGGF 

       130        140        150        160        170        180 
MAVPMPVQPK SKTPQSSGFS NPAYDMSTVS SRTSSWVQSQ NSLRSVSPFH RQALQTVWVT 

       190        200        210 
PPGSTSSSSV SSTPYGVFNT DRMPLFANLR R 

« Hide

References

[1]"Sequence and genome organization of a human small round-structured (Norwalk-like) virus."
Lambden P.R., Caul E.O., Ashley C.R., Clarke I.N.
Science 259:516-519(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L07418 Genomic RNA. Translation: AAA92985.1.
PIRC37491.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR004278. RNA_pol/capsid.
[Graphical view]
PfamPF03035. RNA_capsid. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameVP2_SOUV3
AccessionPrimary (citable) accession number: Q04550
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 29, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families