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Q04550

- VP2_SOUV3

UniProt

Q04550 - VP2_SOUV3

Protein

Protein VP2

Gene

ORF3

Organism
Southampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 38 (01 Oct 2014)
      Sequence version 1 (01 Oct 1994)
      Previous versions | rss
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    Functioni

    Minor structural protein present in one or two copies per virion. Stabilizes capsid protein VP1 by protecting it from disassembly and degradation. May play a role in RNA genome packaging By similarity.By similarity

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Protein VP2
    Alternative name(s):
    Minor capsid protein
    Gene namesi
    ORF Names:ORF3
    OrganismiSouthampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK)
    Taxonomic identifieri37129 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    ProteomesiUP000007226: Genome

    Subcellular locationi

    Virion. Host cytoplasm By similarity

    GO - Cellular componenti

    1. host cell cytoplasm Source: UniProtKB-SubCell
    2. virion Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Host cytoplasm, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 211211Protein VP2PRO_0000100131Add
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the norovirus VP2 family.Curated

    Family and domain databases

    InterProiIPR004278. RNA_pol/capsid.
    [Graphical view]
    PfamiPF03035. RNA_capsid. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04550-1 [UniParc]FASTAAdd to Basket

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    MAQAIIGAIA ASAAGSALGA GIQAGAEAAL QSQRYQQDLA LQRNTFEHDK    50
    DMLSYQVQAS NALLAKNLNT RYSMLIAGGL SSADASRAVA GAPVTRLIDW 100
    NGTRVAAPRS SATTLRSGGF MAVPMPVQPK SKTPQSSGFS NPAYDMSTVS 150
    SRTSSWVQSQ NSLRSVSPFH RQALQTVWVT PPGSTSSSSV SSTPYGVFNT 200
    DRMPLFANLR R 211
    Length:211
    Mass (Da):22,257
    Last modified:October 1, 1994 - v1
    Checksum:i3D6D1B51CC3C27B4
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L07418 Genomic RNA. Translation: AAA92985.1.
    PIRiC37491.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    L07418 Genomic RNA. Translation: AAA92985.1 .
    PIRi C37491.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR004278. RNA_pol/capsid.
    [Graphical view ]
    Pfami PF03035. RNA_capsid. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and genome organization of a human small round-structured (Norwalk-like) virus."
      Lambden P.R., Caul E.O., Ashley C.R., Clarke I.N.
      Science 259:516-519(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiVP2_SOUV3
    AccessioniPrimary (citable) accession number: Q04550
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 1, 1994
    Last sequence update: October 1, 1994
    Last modified: October 1, 2014
    This is version 38 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Miscellaneous

    Translated by a ribosomal termination-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3