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Q04550

- VP2_SOUV3

UniProt

Q04550 - VP2_SOUV3

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Protein

Protein VP2

Gene
ORF3
Organism
Southampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Minor structural protein present in one or two copies per virion. Stabilizes capsid protein VP1 by protecting it from disassembly and degradation. May play a role in RNA genome packaging By similarity.

Names & Taxonomyi

Protein namesi
Recommended name:
Protein VP2
Alternative name(s):
Minor capsid protein
Gene namesi
ORF Names:ORF3
OrganismiSouthampton virus (strain GI/Human/United Kingdom/Southampton/1991) (SHV) (Hu/NV/SHV/1991/UK)
Taxonomic identifieri37129 [NCBI]
Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageCaliciviridaeNorovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
ProteomesiUP000007226: Genome

Subcellular locationi

Virion. Host cytoplasm By similarity

GO - Cellular componenti

  1. host cell cytoplasm Source: UniProtKB-SubCell
  2. virion Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Host cytoplasm, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 211211Protein VP2PRO_0000100131Add
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the norovirus VP2 family.

Family and domain databases

InterProiIPR004278. RNA_pol/capsid.
[Graphical view]
PfamiPF03035. RNA_capsid. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q04550-1 [UniParc]FASTAAdd to Basket

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MAQAIIGAIA ASAAGSALGA GIQAGAEAAL QSQRYQQDLA LQRNTFEHDK    50
DMLSYQVQAS NALLAKNLNT RYSMLIAGGL SSADASRAVA GAPVTRLIDW 100
NGTRVAAPRS SATTLRSGGF MAVPMPVQPK SKTPQSSGFS NPAYDMSTVS 150
SRTSSWVQSQ NSLRSVSPFH RQALQTVWVT PPGSTSSSSV SSTPYGVFNT 200
DRMPLFANLR R 211
Length:211
Mass (Da):22,257
Last modified:October 1, 1994 - v1
Checksum:i3D6D1B51CC3C27B4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L07418 Genomic RNA. Translation: AAA92985.1.
PIRiC37491.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L07418 Genomic RNA. Translation: AAA92985.1 .
PIRi C37491.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

InterProi IPR004278. RNA_pol/capsid.
[Graphical view ]
Pfami PF03035. RNA_capsid. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Sequence and genome organization of a human small round-structured (Norwalk-like) virus."
    Lambden P.R., Caul E.O., Ashley C.R., Clarke I.N.
    Science 259:516-519(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Entry informationi

Entry nameiVP2_SOUV3
AccessioniPrimary (citable) accession number: Q04550
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 1, 1994
Last sequence update: October 1, 1994
Last modified: May 29, 2013
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Miscellaneous

Translated by a ribosomal termination-reinitiation process from the bicistronic mRNA coding for VP1 and VP2.

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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