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Reviewed, UniProtKB/Swiss-Prot Q04545 (YMI1_YEAST)

Last modified November 24, 2009. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Zinc finger protein YML081W
Gene names
Ordered Locus Names: YML081W
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length1251 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

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General annotation (Comments)

Subcellular location

Nucleus Potential.

Miscellaneous

Present with 672 molecules/cell in log phase SD medium. Ref.2

Sequence similarities

Contains 2 C2H2-type zinc fingers.

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Ontologies

Keywords
   Cellular componentNucleus
   DomainRepeat
Zinc-finger
   LigandDNA-binding
Metal-binding
Zinc
   PTMPhosphoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular componentnucleus

Inferred from direct assay. Source: SGD

   Molecular functionprotein binding

Inferred from physical interaction. Source: IntAct

sequence-specific DNA binding

Inferred from direct assay. Source: SGD

zinc ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

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Binary interactions

With

Entry

#Exp.

IntAct

Notes

TAO3P404681EBI-27891,EBI-18961

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 12511251Zinc finger protein YML081W
PRO_0000046864

Regions

Zinc finger61 – 8323C2H2-type 1
Zinc finger89 – 11224C2H2-type 2

Amino acid modifications

Modified residue1801Phosphoserine Ref.5
Modified residue2701Phosphothreonine Ref.5
Modified residue5271Phosphoserine Ref.5 Ref.3 Ref.4
Modified residue6031Phosphoserine Ref.5

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Sequences

Sequence LengthMass (Da)Tools
Q04545-1 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 612F064177D6FF3B

FASTA1,251141,465
        10         20         30         40         50         60 
MSSEEFKGLP IKRDISSTIY ADRPPALSAP PCVGATGNDK IQVLPIPKKS RTIKTDKPRP 

        70         80         90        100        110        120 
FLCHICTRGF VRQEHLKRHQ RAHTNEKPFL CVFCGRCFAR RDLVLRHQHK LHSALVSKES 

       130        140        150        160        170        180 
INSKDKTEID AINDKNIIQI QGNKQTILPT PSNPLAKTAV QLKKAAKEKK NGKQGKLDLS 

       190        200        210        220        230        240 
PSYGANNHST DVSPSVGNSS TPAVIEETDS SSHFPLPDTN IPTKSKRHAS FSASSAFTYS 

       250        260        270        280        290        300 
SDNFQKLHQQ AKSDFDELQE SIPHQVGFST PQLTAQQLIE NAIESGVVDL ETLDLPPFLS 

       310        320        330        340        350        360 
LDGLPPASSS AAVAASEQID ICPSSATDTI SGANSTPNQA ATAPPFQLPI ARESSSLFLA 

       370        380        390        400        410        420 
NTPYLSDFLT MGSSYGGSGG FAKSITADPS LDYFNYKNHS HPDSRHNNSS SGINYSNNKN 

       430        440        450        460        470        480 
NNESIEKSQN NSNVINETID HTDIHAHHAD AHDDSFIESE EWLSKFIMDS QIDNDLKLNI 

       490        500        510        520        530        540 
NHFNDIGFNN LHPQNPTTHS EPRNMHNENR DMHRSASKFQ SVSENISPRE QMSLFKTKQN 

       550        560        570        580        590        600 
KAISKFLSDE KIPSTASPSS SASPVQFDKK NVDINEFLLD ESVSNLFTTR QIDLFKKNVN 

       610        620        630        640        650        660 
LYSPLFQNQK DAVSSTSLTP SLTTQTATTQ SGPGWTDSSQ KLTFFTEQLR NLIIKENNLK 

       670        680        690        700        710        720 
SNLFPTVDEL NHYVDLYQVE FHKYFPFIHL YSIIPSSENY PLVISISMIG ALYGFHSTHA 

       730        740        750        760        770        780 
LLLSKIARTR VRMFLENTRS NHDKTPIWLM QSLVLLTFTS IFSNDMNAFR TVNTQIMILV 

       790        800        810        820        830        840 
QLIKISKLNY PLENFIKPPI ESDHVLEYQD NPAVLNQFKA QYNTREQINR NFKYFILAQS 

       850        860        870        880        890        900 
RIRICHIVLL ISNLFKSLVD FDCCFHSIDL KCGVPCYNEV LFFCENSRTW NENLTRFNIV 

       910        920        930        940        950        960 
LDSKFSLIEV SNGESNYEKC LMYLSNGNPY LYKNAKISFK TLLSLLISIH EKINIERDAL 

       970        980        990       1000       1010       1020 
KDSYESDFHA KNVQWRMHSR PLVATMLKHW ELLYIKNGGI LALSDENLPI INTNPSFRLI 

      1030       1040       1050       1060       1070       1080 
IPLYFFAKLR KCLDIAPTLR CIWNQDWNSM NSSLEKVCYE RESLREATEY AVSVITFWID 

      1090       1100       1110       1120       1130       1140 
TVSVMKGKST QTPIFTITCI FVSILVIAGY MRRLEDFAQN KNSDCMIGSL KSTDRILWLK 

      1150       1160       1170       1180       1190       1200 
AFKTLKRIES HLSEREYKLQ TFAEFLRVPD NGSLDIESLD SSLIENTLNS HDVTNQALDI 

      1210       1220       1230       1240       1250 
ITRTRLSSRT LYCGARILGD TPVWPVSLLF AHALQSRAIY NINHRKSVNS V

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References

[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII."
Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. expand/collapse author list , Skelton J., Walsh S.V., Whitehead S., Barrell B.G.
Nature 387:90-93(1997) [PubMed: 9169872] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204511 / S288c / AB972.
[2]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[3]"Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway."
Gruhler A., Olsen J.V., Mohammed S., Mortensen P., Faergeman N.J., Mann M., Jensen O.N.
Mol. Cell. Proteomics 4:310-327(2005) [PubMed: 15665377] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-527, MASS SPECTROMETRY.
[4]"Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae."
Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P.
J. Proteome Res. 6:1190-1197(2007) [PubMed: 17330950] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-527, MASS SPECTROMETRY.
[5]"A multidimensional chromatography technology for in-depth phosphoproteome analysis."
Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.
Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-180; THR-270; SER-527 AND SER-603, MASS SPECTROMETRY.
+Additional computationally mapped references.

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Cross-references

Sequence databases

Z46660 Genomic DNA. Translation: CAA86657.1.
Z46373 Genomic DNA. Translation: CAA86497.1.
PIRS49645.
RefSeqNP_013630.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

IntActQ04545. 1 interaction.
STRINGQ04545.

Proteomic databases

PeptideAtlasQ04545.
PRIDEQ04545.

Genome annotation databases

EnsemblYML081W; YML081W; YML081W; Saccharomyces cerevisiae. [Genome view]
GeneID854894.
KEGGsce:YML081W.
NMPDRfig|4932.3.peg.4667.

Organism-specific databases

CYGDYML081w.
SGDS000004546. YML081W.

Phylogenomic databases

HOGENOMQ04545.
OMADYFIMAQ
OrthoDBEOG9CG1RB

Gene expression databases

ArrayExpressQ04545.
GenevestigatorQ04545.
GermOnlineYML081W. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
Gene3DG3DSA:3.30.160.60. Znf_C2H2/integrase_DNA-bd. 1 hit.
PfamPF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTSM00355. ZnF_C2H2. 2 hits.
[Graphical view]
PROSITEPS00028. ZINC_FINGER_C2H2_1. 2 hits.
PS50157. ZINC_FINGER_C2H2_2. 2 hits.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio977858.

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Entry information

Entry nameYMI1_YEAST
AccessionPrimary (citable) accession number: Q04545
Secondary accession number(s): Q03621
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 24, 2009
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome XIII

Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents