Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q04539

- RPEP_CUPNH

UniProt

Q04539 - RPEP_CUPNH

Protein

Ribulose-phosphate 3-epimerase, plasmid

Gene

cbbEP

Organism
Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.By similarity

    Catalytic activityi

    D-ribulose 5-phosphate = D-xylulose 5-phosphate.

    Cofactori

    Binds 1 divalent metal cation per subunit. Active with Co2+, Fe2+, Mn2+ and Zn2+ By similarity.By similarity

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei21 – 211SubstrateBy similarity
    Metal bindingi46 – 461Divalent metal cationBy similarity
    Active sitei48 – 481Proton acceptorBy similarity
    Metal bindingi48 – 481Divalent metal cationBy similarity
    Metal bindingi79 – 791Divalent metal cationBy similarity
    Binding sitei79 – 791SubstrateBy similarity
    Active sitei192 – 1921Proton donorBy similarity
    Metal bindingi192 – 1921Divalent metal cationBy similarity
    Binding sitei194 – 1941Substrate; via amide nitrogenBy similarity

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW
    2. ribulose-phosphate 3-epimerase activity Source: UniProtKB-EC

    GO - Biological processi

    1. pentose-phosphate shunt Source: InterPro
    2. reductive pentose-phosphate cycle Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Isomerase

    Keywords - Biological processi

    Calvin cycle, Carbohydrate metabolism

    Keywords - Ligandi

    Cobalt, Iron, Manganese, Metal-binding, Zinc

    Enzyme and pathway databases

    BioCyciCNEC381666:GJUJ-6697-MONOMER.
    UniPathwayiUPA00116.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribulose-phosphate 3-epimerase, plasmid (EC:5.1.3.1)
    Alternative name(s):
    Pentose-5-phosphate 3-epimerase
    Short name:
    PPE
    R5P3E
    Gene namesi
    Name:cbbEP
    Synonyms:cfxE
    Ordered Locus Names:PHG423
    Encoded oniPlasmid megaplasmid pHG10 Publication
    OrganismiCupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
    Taxonomic identifieri381666 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeCupriavidus
    ProteomesiUP000008210: Plasmid megaplasmid pHG1

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 241241Ribulose-phosphate 3-epimerase, plasmidPRO_0000171557Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi381666.PHG423.

    Structurei

    3D structure databases

    ProteinModelPortaliQ04539.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni155 – 1584Substrate bindingBy similarity
    Regioni214 – 2152Substrate bindingBy similarity

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiCOG0036.
    HOGENOMiHOG000259347.
    KOiK01783.
    OMAiHATEPNT.
    OrthoDBiEOG67HK17.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    InterProiIPR013785. Aldolase_TIM.
    IPR026019. Ribul_P_3_epim.
    IPR000056. Ribul_P_3_epim-like.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view]
    PANTHERiPTHR11749. PTHR11749. 1 hit.
    PfamiPF00834. Ribul_P_3_epim. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001461. RPE. 1 hit.
    SUPFAMiSSF51366. SSF51366. 1 hit.
    TIGRFAMsiTIGR01163. rpe. 1 hit.
    PROSITEiPS01085. RIBUL_P_3_EPIMER_1. 1 hit.
    PS01086. RIBUL_P_3_EPIMER_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04539-1 [UniParc]FASTAAdd to Basket

    « Hide

    MHATEPNTGH GSQRAIRLAP SILSADFARL GEEVCAIEAG GADLVHFDVM    50
    DNHYVSNLTI GPLVCEAIRP LVSIPIDVHL MVEPVDALIP MFAKAGANLI 100
    SFHPEASRHV DRTIGLIRDH GCKAGLVLNP ATPLSWLDHT LDKLDLVLLM 150
    SVNPGFGGQA FIPGVLDKVR QARARIDRQV AAGGRPVWLE IDGGVKADNI 200
    TEIARAGADT FVAGSAVFGA PDADGGYRGI LHRLREAATI T 241
    Length:241
    Mass (Da):25,594
    Last modified:February 1, 1995 - v1
    Checksum:i6FACA5B81D6734CD
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64172 Genomic DNA. Translation: AAA98231.1.
    AY305378 Genomic DNA. Translation: AAP86172.1.
    RefSeqiNP_943058.1. NC_005241.1.

    Genome annotation databases

    EnsemblBacteriaiAAP86172; AAP86172; PHG423.
    GeneIDi2656542.
    KEGGireh:PHG423.
    PATRICi35229358. VBIRalEut6770_0351.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M64172 Genomic DNA. Translation: AAA98231.1 .
    AY305378 Genomic DNA. Translation: AAP86172.1 .
    RefSeqi NP_943058.1. NC_005241.1.

    3D structure databases

    ProteinModelPortali Q04539.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 381666.PHG423.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP86172 ; AAP86172 ; PHG423 .
    GeneIDi 2656542.
    KEGGi reh:PHG423.
    PATRICi 35229358. VBIRalEut6770_0351.

    Phylogenomic databases

    eggNOGi COG0036.
    HOGENOMi HOG000259347.
    KOi K01783.
    OMAi HATEPNT.
    OrthoDBi EOG67HK17.

    Enzyme and pathway databases

    UniPathwayi UPA00116 .
    BioCyci CNEC381666:GJUJ-6697-MONOMER.

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    InterProi IPR013785. Aldolase_TIM.
    IPR026019. Ribul_P_3_epim.
    IPR000056. Ribul_P_3_epim-like.
    IPR011060. RibuloseP-bd_barrel.
    [Graphical view ]
    PANTHERi PTHR11749. PTHR11749. 1 hit.
    Pfami PF00834. Ribul_P_3_epim. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001461. RPE. 1 hit.
    SUPFAMi SSF51366. SSF51366. 1 hit.
    TIGRFAMsi TIGR01163. rpe. 1 hit.
    PROSITEi PS01085. RIBUL_P_3_EPIMER_1. 1 hit.
    PS01086. RIBUL_P_3_EPIMER_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The Calvin cycle enzyme pentose-5-phosphate 3-epimerase is encoded within the cfx operons of the chemoautotroph Alcaligenes eutrophus."
      Kusian B., Yoo J.-G., Bednarski R., Bowien B.
      J. Bacteriol. 174:7337-7344(1992) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Complete nucleotide sequence of pHG1: a Ralstonia eutropha H16 megaplasmid encoding key enzymes of H(2)-based lithoautotrophy and anaerobiosis."
      Schwartz E., Henne A., Cramm R., Eitinger T., Friedrich B., Gottschalk G.
      J. Mol. Biol. 332:369-383(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 17699 / H16 / DSM 428 / Stanier 337.

    Entry informationi

    Entry nameiRPEP_CUPNH
    AccessioniPrimary (citable) accession number: Q04539
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Plasmid, Reference proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3