Reviewed, UniProtKB/Swiss-Prot Q04516 (YMI7_YEAST)

Names and origin

Protein names

Recommended name:
    Uncharacterized oxidoreductase YML087C
    EC=1.-.-.-

Gene names

Ordered Locus Names:

YML087C

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	312 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Cofactor	FAD By similarity.
Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. Contains 1 FAD-binding FR-type domain.

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane
Ligand	FAD Flavoprotein NAD
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 312	312	Uncharacterized oxidoreductase YML087C		PRO_0000167629
Regions
	Topological domain	1 – 14	14	Extracellular Potential
	Transmembrane	15 – 35	21	Potential
	Topological domain	36 – 41	6	Cytoplasmic Potential
	Transmembrane	42 – 62	21	Potential
	Topological domain	63 – 179	117	Extracellular Potential
	Transmembrane	180 – 200	21	Potential
	Topological domain	201 – 312	112	Cytoplasmic Potential
	Domain	70 – 173	104	FAD-binding FR-type

Sequences

	Sequence		Length	Mass (Da)
	Q04516-1 [UniParc]. Last modified November 1, 1997. Version 1. Checksum: F64DEA3033124EE4	FASTA	312	35,764
	10 20 30 40 50 60 MSIVETCISF VSTNPFYPFC TGLLLNCVVT PLYFWKTQNG RIVVVSLLQF VVLYATAFIS 70 80 90 100 110 120 IGTDKSLYRN KWVALPLSKK TRISRNTSLY CFKLKYPFER LHIPMGYHLA VRVTINGERL 130 140 150 160 170 180 VRYYTPVNVP NTEGHLELVV KTYKHGVVSK YFDKLKIRQY VEFKGPLGEL EYDQDTATEL 190 200 210 220 230 240 GIIAGGSGIT PVLQVLQEII PSPEDLTHIS LIYANETEDD ILMKSQLDHM AKEYPHFKVH 250 260 270 280 290 300 YVIHKPNGKW NGDVGYVTLE EMKRYLPKQA EDHRLLICGP PKMNEMVLNY AKELGWSNGF 310 HKGNGTDKVF VF

References

[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. , Skelton J., Walsh S.V., Whitehead S., Barrell B.G. Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972.
[2]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z46660 Genomic DNA. Translation: CAA86651.1.
PIR	S49640.
RefSeq	NP_013623.1.
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	YML087C; YML087C; YML087C; Saccharomyces cerevisiae. [Genome view]
GeneID	854887.
KEGG	sce:YML087C.
NMPDR	fig|4932.3.peg.4660.
Organism-specific databases
CYGD	YML087c.
SGD	S000004552. YML087C.
Phylogenomic databases
HOGENOM	Q04516.
OMA	YANETED
OrthoDB	EOG9KD84P
Gene expression databases
ArrayExpress	Q04516.
Genevestigator	Q04516.
GermOnline	YML087C. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR017927. Fd_Rdtase_FAD-bd. IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase. IPR001834. NADH-Cyt_B5_reductase. IPR008333. OxRdtase_FAD-bd. IPR001433. OxRdtase_FAD/NAD_bd. IPR017938. Riboflavin_synthase-like_b-brl. [Graphical view]
Pfam	PF00970. FAD_binding_6. 1 hit. PF00175. NAD_binding_1. 1 hit. [Graphical view]
PRINTS	PR00406. CYTB5RDTASE. PR00371. FPNCR.
PROSITE	PS51384. FAD_FR. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	977840.

Entry information

Entry name

YMI7_YEAST

Accession

Primary (citable) accession number: Q04516

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	November 24, 2009
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)