Reviewed,
UniProtKB/Swiss-Prot Q04500 (UTP14_YEAST)
Last modified
November 24, 2009.
Version 69.
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: U3 small nucleolar RNA-associated protein 14 Short name=U3 snoRNA-associated protein 14 Alternative name(s): U three protein 14 | ||||
| Gene names |
| ||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||
| Taxonomic identifier | 4932 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 899 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Involved in nucleolar processing of pre-18S ribosomal RNA. Ref.2 |
| Subunit structure | Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3. Ref.2 |
| Subcellular location | |
| Miscellaneous | Present with 1470 molecules/cell in log phase SD medium. Ref.3 |
| Sequence similarities | Belongs to the UTP14 family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 899 | 899 | U3 small nucleolar RNA-associated protein 14 | PRO_0000065742 | |||||
Regions | |||||||||
| Nucleotide binding | 260 – 267 | 8 | ATP Potential | ||||||
| Compositional bias | 162 – 168 | 7 | Poly-Ser | ||||||
| Compositional bias | 179 – 182 | 4 | Poly-Glu | ||||||
| Compositional bias | 704 – 712 | 9 | Poly-Lys | ||||||
Amino acid modifications | |||||||||
| Modified residue | 34 | 1 | Phosphoserine Ref.4 Ref.6 Ref.7 | ||||||
| Modified residue | 35 | 1 | Phosphoserine Ref.4 Ref.6 Ref.7 | ||||||
| Modified residue | 151 | 1 | Phosphoserine Ref.4 Ref.7 | ||||||
| Modified residue | 423 | 1 | Phosphoserine Ref.4 Ref.6 Ref.7 Ref.5 | ||||||
| Modified residue | 424 | 1 | Phosphoserine Ref.4 Ref.6 Ref.7 Ref.5 | ||||||
| Modified residue | 488 | 1 | Phosphoserine Ref.7 | ||||||
| Modified residue | 500 | 1 | Phosphoserine Ref.6 Ref.7 | ||||||
| Modified residue | 562 | 1 | Phosphoserine Ref.4 Ref.6 Ref.7 | ||||||
| Modified residue | 668 | 1 | Phosphoserine Ref.7 Ref.5 | ||||||
| Modified residue | 738 | 1 | Phosphoserine Ref.4 Ref.7 Ref.5 | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII." Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T., Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K., Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P. Barrell B.G.Nature 387:90-93(1997) [PubMed: 9169872] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204511 / S288c / AB972. |
| [2] | "A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis." Dragon F., Gallagher J.E.G., Compagnone-Post P.A., Mitchell B.M., Porwancher K.A., Wehner K.A., Wormsley S., Settlage R.E., Shabanowitz J., Osheim Y., Beyer A.L., Hunt D.F., Baserga S.J. Nature 417:967-970(2002) [PubMed: 12068309] [Abstract] Cited for: FUNCTION, INTERACTION WITH MPP10 AND SNORNA U3, IDENTIFICATION IN SSU PROCESSOME BY MASS SPECTROMETRY, SUBCELLULAR LOCATION. |
| [3] | "Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. |
| [4] | "Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae." Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., Elias J.E., Gygi S.P. J. Proteome Res. 6:1190-1197(2007) [PubMed: 17330950] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-34; SER-35; SER-151; SER-423; SER-424; SER-562 AND SER-738, MASS SPECTROMETRY. |
| [5] | "Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry." Chi A., Huttenhower C., Geer L.Y., Coon J.J., Syka J.E.P., Bai D.L., Shabanowitz J., Burke D.J., Troyanskaya O.G., Hunt D.F. Proc. Natl. Acad. Sci. U.S.A. 104:2193-2198(2007) [PubMed: 17287358] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-423; SER-424; SER-668 AND SER-738, MASS SPECTROMETRY. |
| [6] | "Proteome-wide identification of in vivo targets of DNA damage checkpoint kinases." Smolka M.B., Albuquerque C.P., Chen S.H., Zhou H. Proc. Natl. Acad. Sci. U.S.A. 104:10364-10369(2007) [PubMed: 17563356] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-34; SER-35; SER-423; SER-424; SER-500 AND SER-562, MASS SPECTROMETRY. |
| [7] | "A multidimensional chromatography technology for in-depth phosphoproteome analysis." Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H. Mol. Cell. Proteomics 7:1389-1396(2008) [PubMed: 18407956] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-34; SER-35; SER-151; SER-423; SER-424; SER-488; SER-500; SER-562; SER-668 AND SER-738, MASS SPECTROMETRY. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| Z46660 Genomic DNA. Translation: CAA86645.1. | |
| PIR | S49634. |
| RefSeq | NP_013617.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:6410N. |
| IntAct | Q04500. 4 interactions. |
| STRING | Q04500. |
Proteomic databases | |
| PRIDE | Q04500. |
Genome annotation databases | |
| Ensembl | YML093W; YML093W; YML093W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 854881. |
| KEGG | sce:YML093W. |
| NMPDR | fig|4932.3.peg.4654. |
Organism-specific databases | |
| CYGD | YML093w. |
| SGD | S000004558. UTP14. |
Phylogenomic databases | |
| HOGENOM | Q04500. |
| OMA | YTSIDEE |
| OrthoDB | EOG908PRB |
Gene expression databases | |
| ArrayExpress | Q04500. |
| Genevestigator | Q04500. |
| GermOnline | YML093W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR006709. SSU_processome_Utp14. [Graphical view] |
| PANTHER | PTHR14150. Utp14. 1 hit. |
| Pfam | PF04615. Utp14. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 977828. |
Entry information
| Entry name | UTP14_YEAST | ||||||||
| Accession | Primary (citable) accession number: Q04500 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome XIII Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names |

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