Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

UniProtKB - Q04500 (UTP14_YEAST)

(max 400 entries)x

Your basket is currently empty. i

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

U3 small nucleolar RNA-associated protein 14

Gene

UTP14

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Involved in nucleolar processing of pre-18S ribosomal RNA.1 Publication

Miscellaneous

Present with 1470 molecules/cell in log phase SD medium.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi260 – 267ATPSequence analysis8

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionRibonucleoprotein
Biological processRibosome biogenesis, rRNA processing
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciYEAST:G3O-32678-MONOMER.
ReactomeiR-SCE-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
U3 small nucleolar RNA-associated protein 14
Short name:
U3 snoRNA-associated protein 14
Alternative name(s):
U three protein 14
Gene namesi
Name:UTP14
Ordered Locus Names:YML093W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces ›
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YML093W.
SGDiS000004558. UTP14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000657421 – 899U3 small nucleolar RNA-associated protein 14Add BLAST899

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei34PhosphoserineCombined sources1
Modified residuei35PhosphoserineCombined sources1
Modified residuei151PhosphoserineCombined sources1
Modified residuei423PhosphoserineCombined sources1
Modified residuei424PhosphoserineCombined sources1
Modified residuei488PhosphoserineCombined sources1
Modified residuei500PhosphoserineCombined sources1
Modified residuei562PhosphoserineCombined sources1
Modified residuei668PhosphoserineCombined sources1
Modified residuei738PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ04500.
PaxDbiQ04500.
PRIDEiQ04500.

PTM databases

iPTMnetiQ04500.

Interactioni

Subunit structurei

Interacts with snoRNA U3. Interacts with MPP10. Component of the ribosomal small subunit (SSU) processome composed of at least 40 protein subunits and snoRNA U3.1 Publication

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi35050. 102 interactors.
DIPiDIP-6410N.
IntActiQ04500. 34 interactors.
MINTiQ04500.
STRINGi4932.YML093W.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5WLCelectron microscopy3.80SS1-899[»]
ProteinModelPortaliQ04500.
SMRiQ04500.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi162 – 168Poly-Ser7
Compositional biasi179 – 182Poly-Glu4
Compositional biasi704 – 712Poly-Lys9

Sequence similaritiesi

Belongs to the UTP14 family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000008142.
HOGENOMiHOG000074497.
InParanoidiQ04500.
KOiK14567.
OMAiTTLPGWG.
OrthoDBiEOG092C1VSC.

Family and domain databases

InterProiView protein in InterPro
IPR006709. SSU_processome_Utp14.
PANTHERiPTHR14150. PTHR14150. 1 hit.
PfamiView protein in Pfam
PF04615. Utp14. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04500-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKKKSKSRS KSSRRVLDAL QLAEREINGE FDNSSDNDKR HDARRNGTVV 
        60         70         80         90        100
NLLKRSKGDT NSDEDDIDSE SFEDEELNSD EALGSDDDYD ILNSKFSQTI 
       110        120        130        140        150
RDKKENANYQ EEEDEGGYTS IDEEDLMPLS QVWDMDEKTA QSNGNDDEDA 
       160        170        180        190        200
SPQLKLQDTD ISSESSSSEE SESESEDDEE EEDPFDEISE DEEDIELNTI 
       210        220        230        240        250
TSKLIDETKS KAPKRLDTYG SGEANEYVLP SANAASGASG KLSLTDMMNV 
       260        270        280        290        300
IDDRQVIENA NLLKGKSSTY EVPLPQRIQQ RHDRKAAYEI SRQEVSKWND 
       310        320        330        340        350
IVQQNRRADH LIFPLNKPTE HNHASAFTRT QDVPQTELQE KVDQVLQESN 
       360        370        380        390        400
LANPEKDSKF EELSTAKMTP EEMRKRTTEM RLMRELMFRE ERKARRLKKI 
       410        420        430        440        450
KSKTYRKIKK KELMKNRELA AVSSDEDNED HDIARAKERM TLKHKTNSKW 
       460        470        480        490        500
AKDMIKHGMT NDAETREEME EMLRQGERLK AKMLDRNSDD EEDGRVQTLS 
       510        520        530        540        550
DVENEEKENI DSEALKSKLG KTGVMNMAFM KNGEAREREA NKETLRQLRA 
       560        570        580        590        600
VENGDDIKLF ESDEEETNGE NIQINKGRRI YTPGSLESNK DMNELNDHTR 
       610        620        630        640        650
KENKVDESRS LENRLRAKNS GQSKNARTNA EGAIIVEEES DGEPLQDGQN 
       660        670        680        690        700
NQQDEEAKDV NPWLANESDE EHTVKKQSSK VNVIDKDSSK NVKAMNKMEK 
       710        720        730        740        750
AELKQKKKKK GKSNDDEDLL LTADDSTRLK IVDPYGGSDD EQGDNVFMFK 
       760        770        780        790        800
QQDVIAEAFA GDDVVAEFQE EKKRVIDDED DKEVDTTLPG WGEWAGAGSK 
       810        820        830        840        850
PKNKKRKFIK KVKGVVNKDK RRDKNLQNVI INEKVNKKNL KYQSSAVPFP 
       860        870        880        890 
FENREQYERS LRMPIGQEWT SRASHQELIK PRIMTKPGQV IDPLKAPFK
Length:899
Mass (Da):103,023
Last modified:November 1, 1997 - v1
Checksum:i0D4FC90D1CB3CFF1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z46660 Genomic DNA. Translation: CAA86645.1.
BK006946 Genomic DNA. Translation: DAA09806.1.
PIRiS49634.
RefSeqiNP_013617.1. NM_001182452.1.

Genome annotation databases

EnsemblFungiiYML093W; YML093W; YML093W.
GeneIDi854881.
KEGGisce:YML093W.

Similar proteinsi

Entry informationi

Entry nameiUTP14_YEAST
AccessioniPrimary (citable) accession number: Q04500
Secondary accession number(s): D6W0J2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: March 28, 2018
This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome