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Q04469 (GUN1_CRYFL) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Endoglucanase 1

EC=3.2.1.4
Alternative name(s):
Carboxymethyl-cellulase 1
Short name=CMCase 1
Short name=Cellulase 1
Endo-1,4-beta-glucanase 1
Gene names
Name:CMC1
OrganismCryptococcus flavus
Taxonomic identifier5416 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaTremellomycetesTremellalesmitosporic TremellalesCryptococcus

Protein attributes

Sequence length341 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Has endoglucanase activity on carboxymethyl-cellulose (CMC).

Catalytic activity

Endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.

Sequence similarities

Belongs to the glycosyl hydrolase 5 (cellulase A) family.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMCleavage on pair of basic residues
Gene Ontology (GO)
   Biological_processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functioncellulase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1616 Potential
Propeptide17 – 3014 Potential
PRO_0000007855
Chain31 – 341311Endoglucanase 1
PRO_0000007856

Sites

Active site1661Proton donor By similarity
Active site2751Nucleophile By similarity

Sequences

Sequence LengthMass (Da)Tools
Q04469 [UniParc].

Last modified October 1, 1996. Version 1.
Checksum: 4A62E45C952DD120

FASTA34135,717
        10         20         30         40         50         60 
MKTATLLAAL SVLAGALAAP LAGDSALHRR SLPRLGGVNL AGCDFGIDIY GNSGTPACPG 

        70         80         90        100        110        120 
TEQVGHFIAD GANLFRLPAG WQYLVGNNQA STSLAPDFFA QYDALVQAVI SKGAYAIIDV 

       130        140        150        160        170        180 
HNYARWNGAI IGQGGPSNQD FANLWTLLAT KVTSNDPNVI FGLMNEPHDL DVSTWAGSVQ 

       190        200        210        220        230        240 
AAVNAIRAAG ATSQYILIPG TGFTNANAWF QGQDNALLGV TDPVGGTDKL LLDVHRYNDV 

       250        260        270        280        290        300 
DFSGTHAECT TNSLDVLSSL DSWLKGNGRK AIVSETGGGH TTSCETDLGE FLNGIKEDYP 

       310        320        330        340 
SVLGFAVWAA GSFDPSYVLS ITPTNGVDNQ LFDIAVKPNL P 

« Hide

References

[1]"Cloning and molecular analysis of cDNA encoding a carboxymethylcellulase of the yeast Cryptococcus flavus."
Cui Z., Mochizuki D., Matsuno Y., Nakamura T., Liu Y., Hatano T., Fukui S., Miyakawa T.
Biosci. Biotechnol. Biochem. 56:1230-1235(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D13967 mRNA. Translation: BAA03070.1.
S45137 Genomic DNA. Translation: AAC60541.1.
PIRJC1201.

3D structure databases

ProteinModelPortalQ04469.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH5. Glycoside Hydrolase Family 5.
mycoCLAPEGL5A_CRYFL.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.20.20.80. 1 hit.
InterProIPR001547. Glyco_hydro_5.
IPR018087. Glyco_hydro_5_CS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF00150. Cellulase. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 1 hit.
PROSITEPS00659. GLYCOSYL_HYDROL_F5. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGUN1_CRYFL
AccessionPrimary (citable) accession number: Q04469
Entry history
Integrated into UniProtKB/Swiss-Prot: October 1, 1996
Last sequence update: October 1, 1996
Last modified: October 16, 2013
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries