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Q04452

- COX4_BACPE

UniProt

Q04452 - COX4_BACPE

Protein

Cytochrome c oxidase subunit 4B

Gene

ctaF

Organism
Bacillus pseudofirmus (strain OF4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
  1. Functioni

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Enzyme and pathway databases

    BioCyciBPSE398511:GJI9-2591-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 4B (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome aa3 subunit 4B
    Cytochrome c oxidase polypeptide IVB
    Gene namesi
    Name:ctaF
    Ordered Locus Names:BpOF4_00900
    OrganismiBacillus pseudofirmus (strain OF4)
    Taxonomic identifieri398511 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001544: Chromosome

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 114114Cytochrome c oxidase subunit 4BPRO_0000183900Add
    BLAST

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei29 – 4921HelicalSequence AnalysisAdd
    BLAST
    Transmembranei56 – 7621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei89 – 10921HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    HOGENOMiHOG000261855.
    KOiK02277.

    Family and domain databases

    InterProiIPR005171. Cyt_c_oxidase_su4_prok.
    [Graphical view]
    PfamiPF03626. COX4_pro. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04452-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADNLSQSFD KSAMTEEERR HIKKEIRKQI VVFALMIFLT LMSFMAVATD    50
    VIPRSFAIPF IFILAVIQFA LQLFFFMHMK DKDHGWANAF MISGIFITVP 100
    TIAALMLLLG VNKI 114
    Length:114
    Mass (Da):13,045
    Last modified:June 15, 2010 - v2
    Checksum:iFEE7A03352BF648D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti32 – 321V → A in AAA22367. (PubMed:7678007)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M94110 Genomic DNA. Translation: AAA22367.1.
    CP001878 Genomic DNA. Translation: ADC48249.1.
    RefSeqiWP_012959531.1. NC_013791.2.
    YP_003425141.1. NC_013791.2.

    Genome annotation databases

    EnsemblBacteriaiADC48249; ADC48249; BpOF4_00900.
    GeneIDi8765152.
    KEGGibpf:BpOF4_00900.
    PATRICi31942826. VBIBacPse80461_0175.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    M94110 Genomic DNA. Translation: AAA22367.1 .
    CP001878 Genomic DNA. Translation: ADC48249.1 .
    RefSeqi WP_012959531.1. NC_013791.2.
    YP_003425141.1. NC_013791.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ADC48249 ; ADC48249 ; BpOF4_00900 .
    GeneIDi 8765152.
    KEGGi bpf:BpOF4_00900.
    PATRICi 31942826. VBIBacPse80461_0175.

    Phylogenomic databases

    HOGENOMi HOG000261855.
    KOi K02277.

    Enzyme and pathway databases

    BioCyci BPSE398511:GJI9-2591-MONOMER.

    Family and domain databases

    InterProi IPR005171. Cyt_c_oxidase_su4_prok.
    [Graphical view ]
    Pfami PF03626. COX4_pro. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of the cta operon from alkaliphilic Bacillus firmus OF4 and characterization of the pH-regulated cytochrome caa3 oxidase it encodes."
      Quirk P.G., Hicks D.B., Krulwich T.A.
      J. Biol. Chem. 268:678-685(1993) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    2. "Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4."
      Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J., Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B., Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G.
      , Xue Y., Ma Y., Hu F.Z., Krulwich T.A.
      Environ. Microbiol. 13:3289-3309(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: OF4.

    Entry informationi

    Entry nameiCOX4_BACPE
    AccessioniPrimary (citable) accession number: Q04452
    Secondary accession number(s): D3FU47
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1994
    Last sequence update: June 15, 2010
    Last modified: October 1, 2014
    This is version 72 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3