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Q04442 (COX3_BACPE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome aa3 subunit 3
Cytochrome c oxidase polypeptide III
Gene names
Name:ctaE
Ordered Locus Names:BpOF4_00905
OrganismBacillus pseudofirmus (strain OF4) [Complete proteome] [HAMAP]
Taxonomic identifier398511 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus

Protein attributes

Sequence length206 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Keywords
   Cellular componentCell membrane
Membrane
   DomainTransmembrane
Transmembrane helix
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processaerobic electron transport chain

Inferred from electronic annotation. Source: InterPro

   Cellular_componentintegral component of membrane

Inferred from electronic annotation. Source: UniProtKB-KW

plasma membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functioncytochrome-c oxidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 206206Cytochrome c oxidase subunit 3
PRO_0000183875

Regions

Transmembrane26 – 4621Helical; Potential
Transmembrane68 – 8821Helical; Potential
Transmembrane97 – 11721Helical; Potential
Transmembrane143 – 16321Helical; Potential
Transmembrane185 – 20521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q04442 [UniParc].

Last modified February 1, 1994. Version 1.
Checksum: B30CA3D359FC4483

FASTA20622,856
        10         20         30         40         50         60 
MAGAVDTSKG LPSHPERATL EGKNKFLGFW FFLGGETILF ATFFGTFLGL RGGTADGPTS 

        70         80         90        100        110        120 
ADLVALDLVF IMTMLLLTSS LTSVLAMFAM KKNNFKAMMI WMWITVVLGL AFLGFEIYEF 

       130        140        150        160        170        180 
HHYVVDYQFG FSTSAFASAF YSLVGLHGAH VAFGLSWIIV LLIRYRKSGI TLTNAPKFYV 

       190        200 
AGLYWHFIDV VWVFIFTVVY LMGVGG 

« Hide

References

« Hide 'large scale' references
[1]"Cloning of the cta operon from alkaliphilic Bacillus firmus OF4 and characterization of the pH-regulated cytochrome caa3 oxidase it encodes."
Quirk P.G., Hicks D.B., Krulwich T.A.
J. Biol. Chem. 268:678-685(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Genome of alkaliphilic Bacillus pseudofirmus OF4 reveals adaptations that support the ability to grow in an external pH range from 7.5 to 11.4."
Janto B., Ahmed A., Ito M., Liu J., Hicks D.B., Pagni S., Fackelmayer O.J., Smith T.A., Earl J., Elbourne L.D., Hassan K., Paulsen I.T., Kolsto A.B., Tourasse N.J., Ehrlich G.D., Boissy R., Ivey D.M., Li G. expand/collapse author list , Xue Y., Ma Y., Hu F.Z., Krulwich T.A.
Environ. Microbiol. 13:3289-3309(2011) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: OF4.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
M94110 Genomic DNA. Translation: AAA22366.1.
CP001878 Genomic DNA. Translation: ADC48250.1.
RefSeqYP_003425142.1. NC_013791.2.

3D structure databases

ProteinModelPortalQ04442.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaADC48250; ADC48250; BpOF4_00905.
GeneID8765153.
KEGGbpf:BpOF4_00905.
PATRIC31942828. VBIBacPse80461_0176.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHOG000086398.
KOK02276.

Enzyme and pathway databases

BioCycBPSE398511:GJI9-2592-MONOMER.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_BACPE
AccessionPrimary (citable) accession number: Q04442
Secondary accession number(s): D3FU48
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1994
Last sequence update: February 1, 1994
Last modified: May 14, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families