Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q04432 (HSP31_YEAST)

Last modified November 3, 2009. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (4) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Probable chaperone protein HSP31
    EC=3.2.-.-
Alternative name(s):
    Heat shock protein 31
Gene names
Name: HSP31
Ordered Locus Names: YDR533C
ORF Names: D9719.36
OrganismSaccharomyces cerevisiae (Baker's yeast) [Complete proteome]
Taxonomic identifier4932 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Hide | Top

Protein attributes

Sequence length237 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

Hide | Top

General annotation (Comments)

Function

Probable protease. May act as a chaperone.

Subunit structure

Homodimer. Ref.3 Ref.4

Miscellaneous

Cys-138 is easily oxidized to sulfinic acid.

Present with 358 molecules/cell in log phase SD medium. Ref.2

Sequence similarities

Belongs to the peptidase C56 family.

Hide | Top

Ontologies

Keywords
   Biological processStress response
   Molecular functionChaperone
Hydrolase
Protease
   PTMOxidation
   Technical term3D-structure
Complete proteome
Gene Ontology (GO)
   Cellular componentsoluble fraction

Inferred from direct assay. Source: SGD

   Molecular functionpeptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

protein binding

Inferred from physical interaction. Source: IntAct

Complete GO annotation...

Hide | Top

Binary interactions

With

Entry

#Exp.

IntAct

Notes

SRP1Q028211EBI-35591,EBI-1797

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 237237Probable chaperone protein HSP31
PRO_0000157852

Sites

Active site1381 Potential
Active site1391 Potential
Active site1701 Potential

Amino acid modifications

Modified residue1381Cysteine sulfinic acid (-SO2H)

Secondary structure

1 ................................................ 237
Helix Strand Turn

Details...

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q04432-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 088697FB888DF7D5

FASTA23725,670
        10         20         30         40         50         60 
MAPKKVLLAL TSYNDVFYSD GAKTGVFVVE ALHPFNTFRK EGFEVDFVSE TGKFGWDEHS 

        70         80         90        100        110        120 
LAKDFLNGQD ETDFKNKDSD FNKTLAKIKT PKEVNADDYQ IFFASAGHGT LFDYPKAKDL 

       130        140        150        160        170        180 
QDIASEIYAN GGVVAAVCHG PAIFDGLTDK KTGRPLIEGK SITGFTDVGE TILGVDSILK 

       190        200        210        220        230 
AKNLATVEDV AKKYGAKYLA PVGPWDDYSI TDGRLVTGVN PASAHSTAVR SIDALKN

« Hide

Hide | Top

References

« Hide 'large scale' references
[1]"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. expand/collapse author list , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
Nature 387:75-78(1997) [PubMed: 9169867] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Global analysis of protein expression in yeast."
Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S.
Nature 425:737-741(2003) [PubMed: 14562106] [Abstract]
Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
[3]"The 1.8-A resolution crystal structure of YDR533Cp from Saccharomyces cerevisiae: a member of the DJ-1/ThiJ/PfpI superfamily."
Wilson M.A., St Amour C.V., Collins J.L., Ringe D., Petsko G.A.
Proc. Natl. Acad. Sci. U.S.A. 101:1531-1536(2004) [PubMed: 14745011] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), SUBUNIT.
[4]"Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family."
Graille M., Quevillon-Cheruel S., Leulliot N., Zhou C.-Z., de la Sierra Gallay I.L., Jacquamet L., Ferrer J.-L., Liger D., Poupon A., Janin J., van Tilbeurgh H.
Structure 12:839-847(2004) [PubMed: 15130476] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.85 ANGSTROMS), SUBUNIT.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

U33057 Genomic DNA. Translation: AAB64972.1.
PIRS69588.
RefSeqNP_010822.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
1QVVX-ray2.35A/B/C/D1-237[»]
1QVWX-ray1.90A/B1-237[»]
1QVZX-ray1.85A/B1-237[»]
1RW7X-ray1.80A1-237[»]
ModBaseSearch...

Protein-protein interaction databases

DIPDIP:4315N.
IntActQ04432. 6 interactions.
STRINGQ04432.

Protein family/group databases

MEROPSC56.004.

Proteomic databases

PeptideAtlasQ04432.

Genome annotation databases

EnsemblYDR533C; YDR533C; YDR533C; Saccharomyces cerevisiae. [Genome view]
GeneID852146.
GenomeReviewsGene locus YDR533C in contig Z71256_GR.
KEGGsce:YDR533C.
NMPDRfig|4932.3.peg.1599.

Organism-specific databases

CYGDYDR533c.
SGDS000002941. HSP31.

Phylogenomic databases

HOGENOMQ04432.
OMATLFDYPK.

Gene expression databases

ArrayExpressQ04432.
GenevestigatorQ04432.
GermOnlineYDR533C. Saccharomyces cerevisiae.

Family and domain databases

InterProIPR002818. ThiJ/PfpI.
[Graphical view]
PfamPF01965. DJ-1_PfpI. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

NextBio970567.

Hide | Top

Entry information

Entry nameHSP31_YEAST
AccessionPrimary (citable) accession number: Q04432
Entry history
Integrated into UniProtKB/Swiss-Prot: July 19, 2004
Last sequence update: November 1, 1996
Last modified: November 3, 2009
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Hide | Top

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Peptidase families

Classification of peptidase families and list of entries

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Binary interactions · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents