Q043J8 (Q043J8_LACGA) Unreviewed, UniProtKB/TrEMBL
Last modified
May 1, 2013.
Version 49.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize orderNames and origin
| Protein names | Recommended name: Glycerol-3-phosphate acyltransferase HAMAP-Rule MF_01043 Alternative name(s): Acyl-PO4 G3P acyltransferase HAMAP-Rule MF_01043 Acyl-phosphate--glycerol-3-phosphate acyltransferase HAMAP-Rule MF_01043 G3P acyltransferase HAMAP-Rule MF_01043 Lysophosphatidic acid synthase HAMAP-Rule MF_01043 | ||||
| Gene names |
| ||||
| Organism | Lactobacillus gasseri (strain ATCC 33323 / DSM 20243) [Complete proteome] [HAMAP] EMBL ABJ60374.1 | ||||
| Taxonomic identifier | 324831 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › ![]() |
Protein attributes
| Sequence length | 219 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO4) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP By similarity. HAMAP-Rule MF_01043 |
| Catalytic activity | Acyl-phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + phosphate. HAMAP-Rule MF_01043 |
| Pathway | Lipid metabolism; phospholipid metabolism. HAMAP-Rule MF_01043 SAAS SAAS003811 |
| Subunit structure | Probably interacts with PlsX By similarity. HAMAP-Rule MF_01043 SAAS SAAS003811 |
| Subcellular location | Cell membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01043. |
| Sequence similarities | Belongs to the PlsY family. HAMAP-Rule MF_01043 |
Ontologies
| Keywords | |
|---|---|
| Biological process | Lipid biosynthesis Lipid metabolism Phospholipid biosynthesis HAMAP-Rule MF_01043 SAAS SAAS003811 Phospholipid metabolism |
| Cellular component | Cell membrane HAMAP-Rule MF_01043 SAAS SAAS003811 Membrane |
| Domain | Transmembrane Transmembrane helix HAMAP-Rule MF_01043 SAAS SAAS003811 |
| Molecular function | Acyltransferase EMBL ABJ60374.1 Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological_process | phospholipid biosynthetic process Inferred from electronic annotation. Source: HAMAP |
| Cellular_component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membraneInferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | acyl-phosphate glycerol-3-phosphate acyltransferase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Regions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Transmembrane | 6 – 26 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
| Transmembrane | 50 – 70 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
| Transmembrane | 85 – 105 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
| Transmembrane | 115 – 135 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
| Transmembrane | 136 – 156 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
| Transmembrane | 159 – 179 | 21 | Helical; By similarity HAMAP-Rule MF_01043 | ||||||
Sequences
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References
| [1] | "Comparative genomics of the lactic acid bacteria." Makarova K., Slesarev A., Wolf Y., Sorokin A., Mirkin B., Koonin E., Pavlov A., Pavlova N., Karamychev V., Polouchine N., Shakhova V., Grigoriev I., Lou Y., Rohksar D., Lucas S., Huang K., Goodstein D.M., Hawkins T. Mills D.Proc. Natl. Acad. Sci. U.S.A. 103:15611-15616(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 33323 / DSM 20243. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | CP000413 Genomic DNA. Translation: ABJ60374.1. |
| RefSeq | YP_814812.1. NC_008530.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 324831.LGAS_0998. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | ABJ60374; ABJ60374; LGAS_0998. |
| GeneID | 4439794. |
| KEGG | lga:LGAS_0998. |
| PATRIC | 22230160. VBILacGas62225_0987. |
Organism-specific databases | |
| CMR | Search... |
Phylogenomic databases | |
| eggNOG | COG0344. |
| HOGENOM | HOG000283807. |
| KO | K08591. |
| OMA | KGIDIRD. |
| ProtClustDB | CLSK2516632. |
Enzyme and pathway databases | |
| BioCyc | LGAS324831:GHTY-1074-MONOMER. |
| UniPathway | UPA00085. |
Family and domain databases | |
| HAMAP | MF_01043. PlsY. |
| InterPro | IPR003811. G3P_acylTferase. [Graphical view] |
| Pfam | PF02660. G3P_acyltransf. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR00023. TIGR00023. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | Q043J8_LACGA | ||||||||
| Accession | Primary (citable) accession number: Q043J8 | ||||||||
| Entry history |
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| Entry status | Unreviewed (UniProtKB/TrEMBL) | ||||||||

Clusters with
