Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q04364

- YMP8_YEAST

UniProt

Q04364 - YMP8_YEAST

Protein

TPR repeat-containing protein YMR018W

Gene

YMR018W

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 102 (01 Oct 2014)
      Sequence version 1 (01 Nov 1997)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Unknown, but in contrast to the closely related PEX5, it is not involved in the binding of type-1 peroxisome-targeting sequences (PTS1) nor in peroxisome biogenesis or fatty acid oxidation.

    Enzyme and pathway databases

    BioCyciYEAST:G3O-32724-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    TPR repeat-containing protein YMR018W
    Gene namesi
    Ordered Locus Names:YMR018W
    ORF Names:YM9711.06
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome XIII

    Organism-specific databases

    CYGDiYMR018w.
    SGDiS000004620. YMR018W.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 514514TPR repeat-containing protein YMR018WPRO_0000106320Add
    BLAST

    Expressioni

    Gene expression databases

    GenevestigatoriQ04364.

    Interactioni

    Subunit structurei

    Interacts according to large scale protein interaction studies with TLG1.Curated

    Protein-protein interaction databases

    BioGridi35189. 8 interactions.
    DIPiDIP-4510N.
    IntActiQ04364. 2 interactions.
    MINTiMINT-490324.
    STRINGi4932.YMR018W.

    Structurei

    3D structure databases

    ProteinModelPortaliQ04364.
    SMRiQ04364. Positions 234-461.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Repeati174 – 20734TPR 1Add
    BLAST
    Repeati218 – 25235TPR 2Add
    BLAST
    Repeati254 – 28633TPR 3Add
    BLAST
    Repeati288 – 32033TPR 4Add
    BLAST
    Repeati326 – 35934TPR 5Add
    BLAST
    Repeati360 – 39334TPR 6Add
    BLAST
    Repeati394 – 42734TPR 7Add
    BLAST
    Repeati429 – 46133TPR 8Add
    BLAST

    Sequence similaritiesi

    Contains 8 TPR repeats.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, TPR repeat

    Phylogenomic databases

    eggNOGiCOG0457.
    GeneTreeiENSGT00390000013941.
    OMAiITEHEVE.
    OrthoDBiEOG76QFSC.

    Family and domain databases

    Gene3Di1.25.40.10. 2 hits.
    InterProiIPR024111. PTS1R_family.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view]
    PANTHERiPTHR10130. PTHR10130. 1 hit.
    SMARTiSM00028. TPR. 3 hits.
    [Graphical view]
    PROSITEiPS50005. TPR. 4 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q04364-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNEVTCSITG DNPIHKINNG LGLKWNNLGK FSDFQTNDSA ARDARTIDYI    50
    FTNCQTGSSI GKIDFRAALP ADKSQHSGVS EKEFSRLENQ WSKEFSCFPK 100
    NKNADVTKPS RNKHEKRSAN LHNRYFAQYY STAYQQNRIY PCRISYNEHS 150
    SVSNGWEFQF KSIENQLLNE LKIENNVEEK TVGYEYVAEY EETIDFMHML 200
    SSVPQTYQFL KSNIYITERD PYKIGCVLMD NGSNLNEVVM AFEAAISQDP 250
    SHINAWLKLG IVNFENESES NGELALRNCL NLDPNNTIAL ENLAIHHINQ 300
    QNESESLKLF HKWILSKFSK VFQPSAGENK DSINKIPKKA HLAHILESLL 350
    NMGIEKKDQY DIYSVLSILY YSDQKIKQSQ KCLEFLLLEK PNNGTIWNRY 400
    GAILANTKSY HSAINAYNKC KQLRPNFTRV RYNLAIAYMN KGDYVKASKM 450
    LIEVILLRSK GYEHNKAKMQ NKFMQNLKNA LIASKNFDSL DLINGSHNTE 500
    SLISTLKAIY NKMD 514
    Length:514
    Mass (Da):59,065
    Last modified:November 1, 1997 - v1
    Checksum:i8A1302220602B64A
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti9 – 91T → P in AAT92739. (PubMed:17322287)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49211 Genomic DNA. Translation: CAA89120.1.
    AY692720 Genomic DNA. Translation: AAT92739.1.
    BK006946 Genomic DNA. Translation: DAA09916.1.
    PIRiS54019.
    RefSeqiNP_013731.1. NM_001182514.1.

    Genome annotation databases

    EnsemblFungiiYMR018W; YMR018W; YMR018W.
    GeneIDi855032.
    KEGGisce:YMR018W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z49211 Genomic DNA. Translation: CAA89120.1 .
    AY692720 Genomic DNA. Translation: AAT92739.1 .
    BK006946 Genomic DNA. Translation: DAA09916.1 .
    PIRi S54019.
    RefSeqi NP_013731.1. NM_001182514.1.

    3D structure databases

    ProteinModelPortali Q04364.
    SMRi Q04364. Positions 234-461.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 35189. 8 interactions.
    DIPi DIP-4510N.
    IntActi Q04364. 2 interactions.
    MINTi MINT-490324.
    STRINGi 4932.YMR018W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YMR018W ; YMR018W ; YMR018W .
    GeneIDi 855032.
    KEGGi sce:YMR018W.

    Organism-specific databases

    CYGDi YMR018w.
    SGDi S000004620. YMR018W.

    Phylogenomic databases

    eggNOGi COG0457.
    GeneTreei ENSGT00390000013941.
    OMAi ITEHEVE.
    OrthoDBi EOG76QFSC.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-32724-MONOMER.

    Miscellaneous databases

    NextBioi 978236.

    Gene expression databases

    Genevestigatori Q04364.

    Family and domain databases

    Gene3Di 1.25.40.10. 2 hits.
    InterProi IPR024111. PTS1R_family.
    IPR013026. TPR-contain_dom.
    IPR011990. TPR-like_helical.
    IPR019734. TPR_repeat.
    [Graphical view ]
    PANTHERi PTHR10130. PTHR10130. 1 hit.
    SMARTi SM00028. TPR. 3 hits.
    [Graphical view ]
    PROSITEi PS50005. TPR. 4 hits.
    PS50293. TPR_REGION. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    3. Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    4. "Identification of PEX5p-related novel peroxisome-targeting signal 1 (PTS1)-binding proteins in mammals."
      Amery L., Sano H., Mannaerts G.P., Snider J., Van Looy J., Fransen M., Van Veldhoven P.P.
      Biochem. J. 357:635-646(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: LACK OF INVOLVEMENT IN PTS1 IMPORT.
    5. "A comprehensive two-hybrid analysis to explore the yeast protein interactome."
      Ito T., Chiba T., Ozawa R., Yoshida M., Hattori M., Sakaki Y.
      Proc. Natl. Acad. Sci. U.S.A. 98:4569-4574(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH TLG1.

    Entry informationi

    Entry nameiYMP8_YEAST
    AccessioniPrimary (citable) accession number: Q04364
    Secondary accession number(s): D6VZJ2, Q6B2L0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: November 1, 1997
    Last modified: October 1, 2014
    This is version 102 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome XIII
      Yeast (Saccharomyces cerevisiae) chromosome XIII: entries and gene names

    External Data

    Dasty 3