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Protein

Mitochondrial intermembrane space cysteine motif-containing protein MIX14

Gene

MIX14

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

  • aerobic respiration Source: SGD
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29646-MONOMER.
ReactomeiREACT_334110. Mitochondrial protein import.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial intermembrane space cysteine motif-containing protein MIX14
Alternative name(s):
Mitochondrial intermembrane space CX(n)C motif protein of 14 kDa
Gene namesi
Name:MIX14
Synonyms:MIC14
Ordered Locus Names:YDR031W
ORF Names:YD9673.01
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
ProteomesiUP000002311 Componenti: Chromosome IV

Organism-specific databases

CYGDiYDR031w.
EuPathDBiFungiDB:YDR031W.
SGDiS000002438. MIX14.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial intermembrane space Source: SGD
  • nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Mitochondrion, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Mitochondrial intermembrane space cysteine motif-containing protein MIX14PRO_0000242621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi63 ↔ 97By similarity
Disulfide bondi73 ↔ 87By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiQ04341.
PaxDbiQ04341.
PeptideAtlasiQ04341.

Interactioni

Protein-protein interaction databases

BioGridi32080. 4 interactions.
DIPiDIP-5131N.
IntActiQ04341. 1 interaction.
MINTiMINT-2928259.
STRINGi4932.YDR031W.

Structurei

3D structure databases

ProteinModelPortaliQ04341.
SMRiQ04341. Positions 8-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 5142CHCH 1Add
BLAST
Domaini56 – 10045CHCH 2Add
BLAST

Sequence similaritiesi

Contains 2 CHCH domains.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiNOG281388.
HOGENOMiHOG000065961.
InParanoidiQ04341.
OMAiQFLAFHQ.
OrthoDBiEOG74TXBN.

Family and domain databases

InterProiIPR010625. CHCH.
IPR016611. UCP013232.
[Graphical view]
PfamiPF06747. CHCH. 1 hit.
[Graphical view]
PIRSFiPIRSF013232. UCP013232. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04341-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDILDEIVI EDVVANCPQE FLQYHKCIRD NEENPGKCKD GRMILSTCIR
60 70 80 90 100
EKVPSVKSIM SECSEPMKKY DQCIRDNMGT RTINENCLGF LQDLRKCAEL
110 120
QVKNKNIKPS INGVNLELIK D
Length:121
Mass (Da):13,866
Last modified:November 1, 1996 - v1
Checksum:i9502632E07FC7916
GO

Sequence cautioni

The sequence CAA98853.1 differs from that shown. Reason: Frameshift at position 117. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68196 Genomic DNA. Translation: CAA92368.1.
Z74327 Genomic DNA. Translation: CAA98853.1. Frameshift.
BK006938 Genomic DNA. Translation: DAA11875.1.
PIRiS67845.
RefSeqiNP_010314.4. NM_001180339.3.

Genome annotation databases

EnsemblFungiiYDR031W; YDR031W; YDR031W.
GeneIDi851595.
KEGGisce:YDR031W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68196 Genomic DNA. Translation: CAA92368.1.
Z74327 Genomic DNA. Translation: CAA98853.1. Frameshift.
BK006938 Genomic DNA. Translation: DAA11875.1.
PIRiS67845.
RefSeqiNP_010314.4. NM_001180339.3.

3D structure databases

ProteinModelPortaliQ04341.
SMRiQ04341. Positions 8-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32080. 4 interactions.
DIPiDIP-5131N.
IntActiQ04341. 1 interaction.
MINTiMINT-2928259.
STRINGi4932.YDR031W.

Proteomic databases

MaxQBiQ04341.
PaxDbiQ04341.
PeptideAtlasiQ04341.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR031W; YDR031W; YDR031W.
GeneIDi851595.
KEGGisce:YDR031W.

Organism-specific databases

CYGDiYDR031w.
EuPathDBiFungiDB:YDR031W.
SGDiS000002438. MIX14.

Phylogenomic databases

eggNOGiNOG281388.
HOGENOMiHOG000065961.
InParanoidiQ04341.
OMAiQFLAFHQ.
OrthoDBiEOG74TXBN.

Enzyme and pathway databases

BioCyciYEAST:G3O-29646-MONOMER.
ReactomeiREACT_334110. Mitochondrial protein import.

Miscellaneous databases

NextBioi969081.
PROiQ04341.

Family and domain databases

InterProiIPR010625. CHCH.
IPR016611. UCP013232.
[Graphical view]
PfamiPF06747. CHCH. 1 hit.
[Graphical view]
PIRSFiPIRSF013232. UCP013232. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The nucleotide sequence of Saccharomyces cerevisiae chromosome IV."
    Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T.
    , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P.
    Nature 387:75-78(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 204508 / S288c.
  2. Cited for: GENOME REANNOTATION.
    Strain: ATCC 204508 / S288c.
  3. Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
  4. "Novel mitochondrial intermembrane space proteins as substrates of the MIA import pathway."
    Gabriel K., Milenkovic D., Chacinska A., Mueller J., Guiard B., Pfanner N., Meisinger C.
    J. Mol. Biol. 365:612-620(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBCELLULAR LOCATION.
  5. Cited for: GENE NAME.

Entry informationi

Entry nameiMIX14_YEAST
AccessioniPrimary (citable) accession number: Q04341
Secondary accession number(s): D6VS15, Q07789
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: June 24, 2015
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.