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Protein

Mitochondrial intermembrane space cysteine motif-containing protein MIX14

Gene

MIX14

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein predictedi

Functioni

GO - Biological processi

  • aerobic respiration Source: SGD
  • protein targeting to mitochondrion Source: Reactome
Complete GO annotation...

Enzyme and pathway databases

BioCyciYEAST:G3O-29646-MONOMER.
ReactomeiR-SCE-1268020. Mitochondrial protein import.

Names & Taxonomyi

Protein namesi
Recommended name:
Mitochondrial intermembrane space cysteine motif-containing protein MIX14
Alternative name(s):
Mitochondrial intermembrane space CX(n)C motif protein of 14 kDa
Gene namesi
Name:MIX14
Synonyms:MIC14
Ordered Locus Names:YDR031W
ORF Names:YD9673.01
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome IV

Organism-specific databases

EuPathDBiFungiDB:YDR031W.
SGDiS000002438. MIX14.

Subcellular locationi

GO - Cellular componenti

  • mitochondrial intermembrane space Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Mitochondrial intermembrane space cysteine motif-containing protein MIX14PRO_0000242621Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi63 ↔ 97By similarity
Disulfide bondi73 ↔ 87By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

MaxQBiQ04341.

Interactioni

Protein-protein interaction databases

BioGridi32080. 5 interactions.
DIPiDIP-5131N.
IntActiQ04341. 1 interaction.
MINTiMINT-2928259.

Structurei

3D structure databases

ProteinModelPortaliQ04341.
SMRiQ04341. Positions 8-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 5142CHCH 1Add
BLAST
Domaini56 – 10045CHCH 2Add
BLAST

Sequence similaritiesi

Contains 2 CHCH domains.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

HOGENOMiHOG000065961.
InParanoidiQ04341.
OMAiQFLAFHQ.
OrthoDBiEOG092C5J2H.

Family and domain databases

InterProiIPR031731. CX9C.
IPR016611. Mix14.
[Graphical view]
PfamiPF16860. CX9C. 2 hits.
[Graphical view]
PIRSFiPIRSF013232. UCP013232. 1 hit.

Sequencei

Sequence statusi: Complete.

Q04341-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDILDEIVI EDVVANCPQE FLQYHKCIRD NEENPGKCKD GRMILSTCIR
60 70 80 90 100
EKVPSVKSIM SECSEPMKKY DQCIRDNMGT RTINENCLGF LQDLRKCAEL
110 120
QVKNKNIKPS INGVNLELIK D
Length:121
Mass (Da):13,866
Last modified:November 1, 1996 - v1
Checksum:i9502632E07FC7916
GO

Sequence cautioni

The sequence CAA98853 differs from that shown. Reason: Frameshift at position 117. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68196 Genomic DNA. Translation: CAA92368.1.
Z74327 Genomic DNA. Translation: CAA98853.1. Frameshift.
BK006938 Genomic DNA. Translation: DAA11875.1.
PIRiS67845.
RefSeqiNP_010314.4. NM_001180339.3.

Genome annotation databases

EnsemblFungiiYDR031W; YDR031W; YDR031W.
GeneIDi851595.
KEGGisce:YDR031W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z68196 Genomic DNA. Translation: CAA92368.1.
Z74327 Genomic DNA. Translation: CAA98853.1. Frameshift.
BK006938 Genomic DNA. Translation: DAA11875.1.
PIRiS67845.
RefSeqiNP_010314.4. NM_001180339.3.

3D structure databases

ProteinModelPortaliQ04341.
SMRiQ04341. Positions 8-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi32080. 5 interactions.
DIPiDIP-5131N.
IntActiQ04341. 1 interaction.
MINTiMINT-2928259.

Proteomic databases

MaxQBiQ04341.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYDR031W; YDR031W; YDR031W.
GeneIDi851595.
KEGGisce:YDR031W.

Organism-specific databases

EuPathDBiFungiDB:YDR031W.
SGDiS000002438. MIX14.

Phylogenomic databases

HOGENOMiHOG000065961.
InParanoidiQ04341.
OMAiQFLAFHQ.
OrthoDBiEOG092C5J2H.

Enzyme and pathway databases

BioCyciYEAST:G3O-29646-MONOMER.
ReactomeiR-SCE-1268020. Mitochondrial protein import.

Miscellaneous databases

PROiQ04341.

Family and domain databases

InterProiIPR031731. CX9C.
IPR016611. Mix14.
[Graphical view]
PfamiPF16860. CX9C. 2 hits.
[Graphical view]
PIRSFiPIRSF013232. UCP013232. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiMIX14_YEAST
AccessioniPrimary (citable) accession number: Q04341
Secondary accession number(s): D6VS15, Q07789
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 1, 1996
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome IV
    Yeast (Saccharomyces cerevisiae) chromosome IV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.