Reviewed, UniProtKB/Swiss-Prot Q04311 (YD049_YEAST)

Names and origin

Protein names

Recommended name:
    Zinc finger protein YDR049W

Gene names

Ordered Locus Names:

YDR049W

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

Protein attributes

Sequence length	632 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Subcellular location	Cytoplasm. Ref.4
Miscellaneous	Present with 3930 molecules/cell in log phase SD medium. Ref.5
Sequence similarities	Contains 1 C2H2-type zinc finger.

Ontologies

Keywords
Cellular component	Cytoplasm
Domain	Coiled coil Zinc-finger
Ligand	Metal-binding Zinc
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	mitochondrion Inferred from direct assay. Source: SGD
Molecular function	zinc ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 632	632	Zinc finger protein YDR049W		PRO_0000244435
Regions
	Zinc finger	72 – 96	25	C2H2-type
	Coiled coil	544 – 582	39	Potential
	Coiled coil	608 – 632	25	Potential
Experimental info
	Sequence conflict	170	1	K → E in AAU09687. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Q04311-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 98A2007E5591A220	FASTA	632	72,733
	10 20 30 40 50 60 MNSQKASKMT GSLKKNDLYI FDLSEQLLNS LKLMSFDSTL REVEVEKTSD NDRNKESGDL 70 80 90 100 110 120 QIARKKVTSN VMRCSVCQMS FDSRNEQKAH YQTDYHLMNV KRNLRGLDIL SVEEFDALIS 130 140 150 160 170 180 KEHGIKSEDE NSGGEQTSSD HEESEEASDR DPDLQTNNYM ETIIENDLQK LGFQKDESDA 190 200 210 220 230 240 ISHINTQSPY IYFKSKYLQK NEVLAIYKSL FNKRSLSNPN EALTFWNSQE NPMAISALFM 250 260 270 280 290 300 VGGGHFAGAI VSHQRLNVKG NAHKKDETLI EQAVNFLEHK TFHRYTTRRK QGGSQSAMDN 310 320 330 340 350 360 AKGKANSAGS ALRRYNESAL KTDIQGVLKD WEPYLSKCDN IFIRARNVSD KKIFTDNTVL 370 380 390 400 410 420 NKGDERIKSF PFTTNRPTVL ELKKAWCELS YLKILPKPEP LAVKETVQKL EVSNKKDEFK 430 440 450 460 470 480 EKQEPLLEEI QTEEIISLLK KGRAPLLISF LKKNKLDGNF RLKPESKYSL TPTMLHYASQ 490 500 510 520 530 540 QGMKQMALIL LSNIKCDPTI KNRLGRTAWD LNRNDDVRHA FQIARYNLGE SFTNWDETHI 550 560 570 580 590 600 GQPLSREQVD EINEKKKAIE NEKAEKLIKL ELEAAKEKQR FAKDAERGPG KKLTNIPSIQ 610 620 630 QQNLNSLTDE QRRRLMREQR ARAAEERMKK KY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The nucleotide sequence of Saccharomyces cerevisiae chromosome IV." Jacq C., Alt-Moerbe J., Andre B., Arnold W., Bahr A., Ballesta J.P.G., Bargues M., Baron L., Becker A., Biteau N., Bloecker H., Blugeon C., Boskovic J., Brandt P., Brueckner M., Buitrago M.J., Coster F., Delaveau T. , del Rey F., Dujon B., Eide L.G., Garcia-Cantalejo J.M., Goffeau A., Gomez-Peris A., Granotier C., Hanemann V., Hankeln T., Hoheisel J.D., Jaeger W., Jimenez A., Jonniaux J.-L., Kraemer C., Kuester H., Laamanen P., Legros Y., Louis E.J., Moeller-Rieker S., Monnet A., Moro M., Mueller-Auer S., Nussbaumer B., Paricio N., Paulin L., Perea J., Perez-Alonso M., Perez-Ortin J.E., Pohl T.M., Prydz H., Purnelle B., Rasmussen S.W., Remacha M.A., Revuelta J.L., Rieger M., Salom D., Saluz H.P., Saiz J.E., Saren A.-M., Schaefer M., Scharfe M., Schmidt E.R., Schneider C., Scholler P., Schwarz S., Soler-Mira A., Urrestarazu L.A., Verhasselt P., Vissers S., Voet M., Volckaert G., Wagner G., Wambutt R., Wedler E., Wedler H., Woelfl S., Harris D.E., Bowman S., Brown D., Churcher C.M., Connor R., Dedman K., Gentles S., Hamlin N., Hunt S., Jones L., McDonald S., Murphy L.D., Niblett D., Odell C., Oliver K., Rajandream M.A., Richards C., Shore L., Walsh S.V., Barrell B.G., Dietrich F.S., Mulligan J.T., Allen E., Araujo R., Aviles E., Berno A., Carpenter J., Chen E., Cherry J.M., Chung E., Duncan M., Hunicke-Smith S., Hyman R.W., Komp C., Lashkari D., Lew H., Lin D., Mosedale D., Nakahara K., Namath A., Oefner P., Oh C., Petel F.X., Roberts D., Schramm S., Schroeder M., Shogren T., Shroff N., Winant A., Yelton M.A., Botstein D., Davis R.W., Johnston M., Andrews S., Brinkman R., Cooper J., Ding H., Du Z., Favello A., Fulton L., Gattung S., Greco T., Hallsworth K., Hawkins J., Hillier L.W., Jier M., Johnson D., Johnston L., Kirsten J., Kucaba T., Langston Y., Latreille P., Le T., Mardis E., Menezes S., Miller N., Nhan M., Pauley A., Peluso D., Rifkin L., Riles L., Taich A., Trevaskis E., Vignati D., Wilcox L., Wohldman P., Vaudin M., Wilson R., Waterston R., Albermann K., Hani J., Heumann K., Kleine K., Mewes H.-W., Zollner A., Zaccaria P. Nature 387:75-78(1997) [PubMed: 9169867] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae." Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F., Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J., Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J. , Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D., LaBaer J. Genome Res. 17:536-543(2007) [PubMed: 17322287] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins." Boehm S., Frishman D., Mewes H.-W. Nucleic Acids Res. 25:2464-2469(1997) [PubMed: 9171100] [Abstract] Cited for: DOMAIN.
[4]	"Global analysis of protein localization in budding yeast." Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., Weissman J.S., O'Shea E.K. Nature 425:686-691(2003) [PubMed: 14562095] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
[5]	"Global analysis of protein expression in yeast." Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N., O'Shea E.K., Weissman J.S. Nature 425:737-741(2003) [PubMed: 14562106] [Abstract] Cited for: LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	Z49209 Genomic DNA. Translation: CAA89079.1. AY723770 Genomic DNA. Translation: AAU09687.1.
PIR	S54034.
RefSeq	NP_010334.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:6303N.
Proteomic databases
PRIDE	Q04311.
Genome annotation databases
Ensembl	YDR049W. Saccharomyces cerevisiae. [Contig view]
GeneID	851618.
GenomeReviews	Gene locus YDR049W in contig Z71256_GR.
KEGG	sce:YDR049W.
NMPDR	fig|4932.3.peg.1079.
Organism-specific databases
CYGD	YDR049w.
SGD	S000002456. YDR049W.
Yeast-GFP	Search...
Phylogenomic databases
HOGENOM	Q04311.
OMA	Q04311. CMIGGGH.
Gene expression databases
GermOnline	YDR049W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR007087. Znf_C2H2. IPR015880. Znf_C2H2-like. [Graphical view]
SMART	SM00355. ZnF_C2H2. 1 hit. [Graphical view]
PROSITE	PS00028. ZINC_FINGER_C2H2_1. 1 hit. PS50157. ZINC_FINGER_C2H2_2. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	969148.

Entry information

Entry name

YD049_YEAST

Accession

Primary (citable) accession number: Q04311
Secondary accession number(s): Q66RH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	November 1, 1996
Last modified:	June 16, 2009
This is version 57 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)