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Q042W5

- Q042W5_LACGA

UniProt

Q042W5 - Q042W5_LACGA

Protein

dTDP-glucose 4,6-dehydratase

Gene

LGAS_1136

Organism
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 60 (01 Oct 2014)
      Sequence version 1 (14 Nov 2006)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O.UniRule annotation

    Cofactori

    NAD.UniRule annotation

    GO - Molecular functioni

    1. coenzyme binding Source: InterPro
    2. dTDP-glucose 4,6-dehydratase activity Source: UniProtKB-EC

    GO - Biological processi

    1. nucleotide-sugar metabolic process Source: InterPro

    Keywords - Molecular functioni

    LyaseUniRule annotationImported

    Enzyme and pathway databases

    BioCyciLGAS324831:GHTY-1136-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    dTDP-glucose 4,6-dehydrataseUniRule annotation (EC:4.2.1.46UniRule annotation)
    Gene namesi
    Ordered Locus Names:LGAS_1136Imported
    OrganismiLactobacillus gasseri (strain ATCC 33323 / DSM 20243)Imported
    Taxonomic identifieri324831 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
    ProteomesiUP000000664: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi324831.LGAS_1136.

    Structurei

    3D structure databases

    ProteinModelPortaliQ042W5.
    SMRiQ042W5. Positions 15-341.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1088.
    HOGENOMiHOG000168006.
    KOiK01710.
    OMAiAETIDWY.
    OrthoDBiEOG6PZXCX.

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR005888. dTDP_Gluc_deHydtase.
    IPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PANTHERiPTHR10366:SF41. PTHR10366:SF41. 1 hit.
    PfamiPF01370. Epimerase. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR01181. dTDP_gluc_dehyt. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q042W5-1 [UniParc]FASTAAdd to Basket

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    MLYTSYELKN IWRNNMKVIV TGGAGFIGSN FIFYMLKKHP DYEIICLDSL    50
    TYAGNLSTLK DVMDNPNFKF VKLDIRDREG VYKLFEEEKP DVVVNFAAES 100
    HVDRSIENPE IFLETNIIGT SVLMDACRKY GIKRFHQVST DEVYGDLPLD 150
    RPDLFFHEDT PLHTSSPYSS SKASADLLVG AYGRTFHLPV TISRCSNNYG 200
    PYQFPEKLIP LMIQRALNNE KLPVYGDGKN VRDWLYVEDH CKAIDLILEK 250
    GTPGEVYNIG GHNEMHNIDI VKLICDYLDK PYSLIEHVTD RKGHDRRYAI 300
    DPEKIHNELG WLPETMFKDG IKKTIQWYLD NKEWWENIIS GDYQNYYDEM 350
    YGKKQVLDKD 360
    Length:360
    Mass (Da):41,842
    Last modified:November 14, 2006 - v1
    Checksum:i78BE1D55D1DA9860
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000413 Genomic DNA. Translation: ABJ60507.1.
    RefSeqiYP_814945.1. NC_008530.1.

    Genome annotation databases

    EnsemblBacteriaiABJ60507; ABJ60507; LGAS_1136.
    GeneIDi4439634.
    KEGGilga:LGAS_1136.
    PATRICi22230436. VBILacGas62225_1125.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000413 Genomic DNA. Translation: ABJ60507.1 .
    RefSeqi YP_814945.1. NC_008530.1.

    3D structure databases

    ProteinModelPortali Q042W5.
    SMRi Q042W5. Positions 15-341.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 324831.LGAS_1136.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABJ60507 ; ABJ60507 ; LGAS_1136 .
    GeneIDi 4439634.
    KEGGi lga:LGAS_1136.
    PATRICi 22230436. VBILacGas62225_1125.

    Phylogenomic databases

    eggNOGi COG1088.
    HOGENOMi HOG000168006.
    KOi K01710.
    OMAi AETIDWY.
    OrthoDBi EOG6PZXCX.

    Enzyme and pathway databases

    BioCyci LGAS324831:GHTY-1136-MONOMER.

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR005888. dTDP_Gluc_deHydtase.
    IPR001509. Epimerase_deHydtase.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    PANTHERi PTHR10366:SF41. PTHR10366:SF41. 1 hit.
    Pfami PF01370. Epimerase. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR01181. dTDP_gluc_dehyt. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 33323 / DSM 20243Imported.

    Entry informationi

    Entry nameiQ042W5_LACGA
    AccessioniPrimary (citable) accession number: Q042W5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 14, 2006
    Last sequence update: November 14, 2006
    Last modified: October 1, 2014
    This is version 60 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteomeImported

    External Data

    Dasty 3