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Q042K0

- G6PI_LACGA

UniProt

Q042K0 - G6PI_LACGA

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Protein

Glucose-6-phosphate isomerase

Gene
pgi, LGAS_1256
Organism
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei288 – 2881Proton donor By similarity
Active sitei309 – 3091 By similarity
Active sitei423 – 4231 By similarity

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciLGAS324831:GHTY-1256-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Alternative name(s):
Phosphoglucose isomerase
Short name:
PGI
Phosphohexose isomerase
Short name:
PHI
Gene namesi
Name:pgi
Ordered Locus Names:LGAS_1256
OrganismiLactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Taxonomic identifieri324831 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
ProteomesiUP000000664: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 447447Glucose-6-phosphate isomeraseUniRule annotationPRO_1000013979Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi324831.LGAS_1256.

Structurei

3D structure databases

ProteinModelPortaliQ042K0.
SMRiQ042K0. Positions 5-446.

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000100403.
KOiK01810.
OMAiGVESYKR.
OrthoDBiEOG64R61J.

Family and domain databases

HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q042K0-1 [UniParc]FASTAAdd to Basket

« Hide

MSKVVHFDAS KLTPFVHENE LKEMQAMVTA ADQELREGTG AGSDFRGWID    50
LPINYDKDEF DRIKKAAKKI QNDSEVLVGI GIGGSYLGAQ ASIEFLNSSF 100
YGREKEKYPT VVFCGNSLSG SYLYDLLEWL GDKDFSINII SKSGTTTEPS 150
IAFRVLKDKL IKKYGKEEAA KRIYATTDRA KGALKTEADA EGYEEFVVPD 200
DIGGRFSVLS AVGLLPIAVA GGDIDAMMKG AADARAAYTD PDVSKDNPYQ 250
YAALRNILYR KGYTTELLEN YEPSLRMFGE WWKQLMGESE GKDQKGIYPS 300
SANFTTDLHS LGQYIQEGRR NLMETVIRVE SPEHDVTIPD DKENLDQLNF 350
LSGKTMNYVN DRAYEGVVLA HTDGGVPVMT VDIENQSAHT LGYLIYWFEL 400
AVGISGYLNG INPFNQPGVE SYKRNMFGLL NKPGYEDLHD DLTKRLK 447
Length:447
Mass (Da):49,857
Last modified:November 14, 2006 - v1
Checksum:i057047AA3002205C
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000413 Genomic DNA. Translation: ABJ60622.1.
RefSeqiYP_815060.1. NC_008530.1.

Genome annotation databases

EnsemblBacteriaiABJ60622; ABJ60622; LGAS_1256.
GeneIDi4439546.
KEGGilga:LGAS_1256.
PATRICi22230683. VBILacGas62225_1246.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000413 Genomic DNA. Translation: ABJ60622.1 .
RefSeqi YP_815060.1. NC_008530.1.

3D structure databases

ProteinModelPortali Q042K0.
SMRi Q042K0. Positions 5-446.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 324831.LGAS_1256.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABJ60622 ; ABJ60622 ; LGAS_1256 .
GeneIDi 4439546.
KEGGi lga:LGAS_1256.
PATRICi 22230683. VBILacGas62225_1246.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000100403.
KOi K01810.
OMAi GVESYKR.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci LGAS324831:GHTY-1256-MONOMER.

Family and domain databases

HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 33323 / DSM 20243.

Entry informationi

Entry nameiG6PI_LACGA
AccessioniPrimary (citable) accession number: Q042K0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 14, 2006
Last modified: June 11, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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